G. Balakrish Nair, Thandavarayan Ramamurthy, Sujit Bhattacharya, Basabjit Dutta et al.
Vibrio parahaemolyticus is recognized as a cause of food-borne gastroenteritis, particularly in the Far East, where raw seafood consumption is high. An unusual increase in admissions of V. parahaemolyticus cases was observed at the Infectious Diseases Hospital in Calcutta, a city in the northeastern...
Emranul Kabir, Monir Uzzaman
Heterocyclic compounds have gained a lot of attention because of their numerous significant medical and biological uses. Research interest on heterocyclic compounds is rapidly increasing due to the extensive synthetic study and functional utility. They are found in more than 90% of novel drugs, and ...
Neal Russell, Anna C. Seale, Megan O’Driscoll, Catherine O’Sullivan et al.
BACKGROUND: Infections such as group B Streptococcus (GBS) are an important cause of maternal sepsis, yet limited data on epidemiology exist. This article, the third of 11, estimates the incidence of maternal GBS disease worldwide. METHODS: We conducted systematic literature reviews (PubMed/Medline,...
D. Scott Merrell, Susan M. Butler, Firdausi Qadri, Nadia Dolganov et al.
The factors that enhance the transmission of pathogens during epidemic spread are ill defined. Water-borne spread of the diarrhoeal disease cholera occurs rapidly in nature, whereas infection of human volunteers with bacteria grown in vitro is difficult in the absence of stomach acid buffering. It i...
Shafiqul Alam Sarker, Shamima Sultana, Gloria Reuteler, D Moine et al.
BACKGROUND: Antibiotic resistance is rising in important bacterial pathogens. Phage therapy (PT), the use of bacterial viruses infecting the pathogen in a species-specific way, is a potential alternative. METHOD: T4-like coliphages or a commercial Russian coliphage product or placebo was orally give...
Jayaseelan Murugaiyan, P. Anand Kumar, G. Srinivasa Rao, Katia Iskandar et al.
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR), continues to evolve and spread beyond all boundaries. As a result, infectious diseases have become more challenging or even impossible to treat, leading to an increase in morbidity and mortality. Despite the failur...
Md. Abdus Salam, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, Jogendra Singh Pawar et al.
Antibiotics are the most magnificent discovery of 20th century that have saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from increasing use and misuse of antibiotics over the years. The tr...
Katia Iskandar, Laurent Molinier, Souheil Hallit, Massimo Sartelli et al.
Data on comprehensive population-based surveillance of antimicrobial resistance is lacking. In low- and middle-income countries, the challenges are high due to weak laboratory capacity, poor health systems governance, lack of health information systems, and limited resources. Developing countries st...
Sachel Mok, Elizabeth A. Ashley, Pedro Eduardo Ferreira, Lei Zhu et al.
Artemisinin resistance in Plasmodium falciparum threatens global efforts to control and eliminate malaria. Polymorphisms in the kelch domain-carrying protein K13 are associated with artemisinin resistance, but the underlying molecular mechanisms are unknown. We analyzed the in vivo transcriptomes of...
Jeanette L. Gehrig, Siddarth Venkatesh, Hao-Wei Chang, Matthew C. Hibberd et al.
To examine the contributions of impaired gut microbial community development to childhood undernutrition, we combined metabolomic and proteomic analyses of plasma samples with metagenomic analyses of fecal samples to characterize the biological state of Bangladeshi children with severe acute malnutr...
Chetan Pandit, Arpita Roy, Suresh Ghotekar, Ameer Khusro et al.
In terms of cost-efficiency, biocompatibility, environmental friendliness, and scalability, green nanoparticle (NP) synthesis is a novel field of nanotechnology that outperforms both physical and chemical approaches. Plants, bacteria, fungi, and algae have lately been used to produce metals and meta...
B. Lobitz, Louisa R. Beck, Anwar Huq, Byron L. Wood et al.
It has long been known that cholera outbreaks can be initiated when Vibrio cholerae, the bacterium that causes cholera, is present in drinking water in sufficient numbers to constitute an infective dose, if ingested by humans. Outbreaks associated with drinking or bathing in unpurified river or brac...
Dilara Islam, Lisa Bandholtz, Jakob Nilsson, Hans Wigzell et al.
Antibacterial peptides are active defense components of innate immunity. Several studies confirm their importance at epithelial surfaces as immediate barrier effectors in preventing infection. Here we report that early in Shigella spp. infections, expression of the antibacterial peptides LL-37 and h...
Jie Liu, Jean Gratz, Caroline Amour, Gibson Kibiki et al.
The TaqMan Array Card (TAC) system is a 384-well singleplex real-time PCR format that has been used to detect multiple infection targets. Here we developed an enteric TaqMan Array Card to detect 19 enteropathogens, including viruses (adenovirus, astrovirus, norovirus GII, rotavirus, and sapovirus), ...
D. Gareth Evans, Doyle J. Evans
Enterotoxigenic Escherichia coli (ETEC) belonging to serogroups O6 and O8 do not possess the H-10407-type colonization factor antigen (CFA/I). However, these frequently isolated ETEC were found to possess a second and distinct heat-labile surface-associated colonization factor antigen, termed CFA/II...