Uta Erdbrügger, Charles J. Blijdorp, Irene V. Bijnsdorp, Francesc E. Borràs et al.
Abstract Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last decade urinary extracellular vesicles (uEVs) were shown to mirror molecular processes as well as physiological...
Ying Bai, Yuan Zhang, Bing Han, Li Yang et al.
Circular RNAs (circRNAs) are highly expressed in the CNS and regulate physiological and pathophysiological processes. However, the potential role of circRNAs in stroke remains largely unknown. Here, we show that the circRNA DLGAP4 (circDLGAP4) functions as an endogenous microRNA-143 (miR-143) sponge...
Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang et al.
N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia. However, the possible involvement of m6A modification of mRNA in hypox...
Aida Shomali, Susmita Das, Namira Arif, Mohammad Sarraf et al.
Flavonoids are characterized as the low molecular weight polyphenolic compounds universally distributed in planta. They are a chemically varied group of secondary metabolites with a broad range of biological activity. The increasing amount of evidence has demonstrated the various physiological funct...
Gous Miah, Mohd Y. Rafii, Mohd Razi Ismail, A. B. Puteh et al.
Blast disease caused by the fungal pathogen Magnaporthe oryzae is the most severe diseases of rice. Using classical plant breeding techniques, breeders have developed a number of blast resistant cultivars adapted to different rice growing regions worldwide. However, the rice industry remains threate...
Jiayu Ma, Xiangshu Piao, Shad Mahfuz, Shenfei Long et al.
The mammalian gut is inhabited by a massive and complicated microbial community, in which the host achieves a stable symbiotic environment through the interdependence, coordination, reciprocal constraints and participation in an immune response. The interaction between the host gut and the microbiot...
Kaixuan Zeng, Bangshun He, Burton B. Yang, Tao Xu et al.
BACKGROUND: Recent studies indicate that circular RNA (circRNA) plays a pivotal role in cancer progression. Here, we sought to investigate its role in breast cancer. METHODS: CircANKS1B (a circRNA originated from exons 5 to 8 of the ANKS1B gene, hsa_circ_0007294) was identified by RNA-sequencing and...
Tanzina Azad, Shoeb Ahmed
Food adulteration is a global concern and developing countries are at higher risk associated with it due to lack of monitoring and policies. However, this is one of the most common phenomena that has been overlooked in many countries. Unfortunately, in contrast to common belief, milk adulterants can...
Jhansi R. Kalluri, Tahir Arbneshi, Sadia Afrin Khan, Adria Neely et al.
Low level: The amount of arsenic in Bangladeshi well water and in bottled drinking water and Mississippi tap water are indicated by a dynamic light scattering (DLS) assay. Label-free gold nanoparticles are used in a selective colorimetric assay (see picture) and in a highly sensitive DLS assay for t...
Mohammad Amzad Hossain, SM Mizanur Rahman
Pineapple has several beneficial properties including antioxidant activity. The fruit of pineapple was extracted with ethyl acetate, methanol and water. The phenolic content of the extracts was determined by Folin–Ciocalteu method and antioxidant activity was assayed through some in vitro models suc...
Audrie Lin, Elisabeth M. Bik, Elizabeth K. Costello, Les Dethlefsen et al.
BACKGROUND: Our current understanding of the composition and stability of the human distal gut microbiota is based largely on studies of infants and adults living in developed countries. In contrast, little is known about the gut microbiota and its variation over time in older children and adolescen...
Rongrong Huang, Lei He, Yanyan Xia, Hongpan Xu et al.
Abstract Emerging evidence indicates that exosomes derived from gastric cancer cells enhance tumor migration and invasion through the modulation of the tumor microenvironment. However, it remains a major problem to detect cancer‐specific exosomes due to technical and biological challenges. Most of t...
Zheng Fan, Yuan Tao, Piao Liu, Lu-Yu Wang et al.
BACKGROUND: The spider Trichonephila antipodiana (Araneidae), commonly known as the batik golden web spider, preys on arthropods with body sizes ranging from ∼2 mm in length to insects larger than itself (>20‒50 mm), indicating its polyphagy and strong dietary detoxification abilities. Although it h...
Amy M. Ehrlich, Alline R. Pacheco, Bethany M. Henrick, Diana H. Taft et al.
BACKGROUND: Bifidobacterium longum subsp. infantis (B. infantis) is a commensal bacterium that colonizes the gastrointestinal tract of breast-fed infants. B. infantis can efficiently utilize the abundant supply of oligosaccharides found in human milk (HMO) to help establish residence. We hypothesize...
Leen Abu‐Safieh, May Alrashed, Shamsa Anazi, Hisham Alkuraya et al.
Retinal dystrophy (RD) is a heterogeneous group of hereditary diseases caused by loss of photoreceptor function and contributes significantly to the etiology of blindness globally but especially in the industrialized world. The extreme locus and allelic heterogeneity of these disorders poses a major...