Yuan Zhang, Rongrong Huang, Mengjing Cheng, Lirui Wang et al.
BACKGROUND: Inflammasomes have been found to interact with the gut microbiota, and this effect is associated with depression, but the mechanisms underlying this interaction have not been elucidated in detail. RESULTS: The locomotor activity of NLRP3 KO mice was significantly greater than that of the...
Mohammad Shoeb
Cancer is a major public health burden in both developed and developing countries. Plant derived agents are being used for the treatment of cancer. Several anticancer agents including taxol, vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, and etoposide derived from ...
Lijun Wang, Wanxiang Lu, Lingyu Ran, Liwen Dou et al.
The secondary cell wall is an important carbon sink in higher plants and its biosynthesis requires coordination of metabolic fluxes in the phenylpropanoid pathway. In Arabidopsis (Arabidopsis thaliana), MYB75 and the KNOX transcription factor KNAT7 form functional complexes to regulate secondary cel...
Mostafa Kamal Masud, Jongbeom Na, Muhammad Younus, Md. Shahriar A. Hossain et al.
The detection of clinically relevant disease-specific biomolecules, including nucleic acids, circulating tumor cells, proteins, antibodies, and extracellular vesicles, has been indispensable to understand their functions in disease diagnosis and prognosis. Therefore, a biosensor for the robust, ultr...
Abdullah Al Mamun, Yanqing Wu, Ilma Monalisa, Chang Jia et al.
BACKGROUND: Currently, spinal cord injury (SCI) is a pathological incident that triggers several neuropathological conditions, leading to the initiation of neuronal damage with several pro-inflammatory mediators' release. However, pyroptosis is recognized as a new programmed cell death mechanism reg...
Md. Abdul Mazid, Carl Ward, Zhiwei Luo, Chuanyu Liu et al.
After fertilization, the quiescent zygote experiences a burst of genome activation that initiates a short-lived totipotent state. Understanding the process of totipotency in human cells would have broad applications. However, in contrast to in mice 1,2 , demonstration of the time of zygotic genome a...
Mohammad Shah Jahan, Guo ShiRong, Jin Sun, Sheng Shu et al.
Photosynthesis is a fundamental biosynthetic process in plants that can enhance carbon absorption and increase crop productivity. Heat stress severely inhibits photosynthetic efficiency. Melatonin is a bio-stimulator capable of regulating diverse abiotic stress tolerances. However, the underlying me...
Md. Mominur Rahman, Fahadul Islam, Md. Harun- Or-Rashid, Abdullah Al Mamun et al.
In the last two decades, considerable interest has been shown in understanding the development of the gut microbiota and its internal and external effects on the intestine, as well as the risk factors for cardiovascular diseases (CVDs) such as metabolic syndrome. The intestinal microbiota plays a pi...
Sarmistha Mitra, Raju Dash
Among all types of cancer, breast cancer is one of the most challenging diseases, which is responsible for a large number of cancer related deaths. Hormonal therapy, surgery, chemotherapy, and radiotherapy have been used as treatment of breast cancer, for a very long time. Due to severe side effects...
Arjun S. Raman, Jeanette L. Gehrig, Siddarth Venkatesh, Hao-Wei Chang et al.
Characterizing the organization of the human gut microbiota is a formidable challenge given the number of possible interactions between its components. Using a statistical approach initially applied to financial markets, we measured temporally conserved covariance among bacterial taxa in the microbi...
Effi Haque, Hiroaki Taniguchi, Md Mahmudul Hassan, Pankaj Bhowmik et al.
The world population is expected to increase from 7.3 to 9.7 billion by 2050. Pest outbreak and increased abiotic stresses due to climate change pose a high risk to tropical crop production. Although conventional breeding techniques have significantly increased crop production and yield, new approac...
M. Saifur Rahman, Md. Shamim Anower, Md. Rabiul Hasan, Md. Biplob Hossain et al.
Zidan Khan, Nikhil Nath, Abdur Rauf, Talha Bin Emran et al.
Currently, available therapeutic medications are both costly as well as not entirely promising in terms of potency. So, new candidates from natural resources are of research interest to find new alternative therapeutics. A well-known combination is a β-sitosterol, a plant-derived nutrient with antic...
David I. Ellis, Howbeer Muhamadali, Simon A. Haughey, Christopher T. Elliott et al.
Major food adulteration and contamination events occur with alarming regularity and are known to be episodic, with the question being not if but when another large-scale food safety/integrity incident will occur.
Md. Sahab Uddin, Abdullah Al Mamun, Badrah S. Alghamdi, Devesh Tewari et al.
Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be mild and slowly aggravated, although other symptoms might demonstrate it as an acute ailment. However, the precise mechanisms of ...