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Field: Molecular Biology

Survey on semi‐tensor product method with its applications in logical networks and other finite‐valued systems

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Jianquan Lu, Haitao Li, Yang Liu, Fangfei Li

Journal: IET Control Theory and Applications 2017
Year:
Citations: 221

This study presents a detailed survey on recent development of logical networks and its applications, including the background of logical networks, the theory of a new matrix product called semi‐tensor product (STP) of matrices, some fundamental works on logical networks, and some current research w...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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The Roles of Cancer Stem Cells and Therapy Resistance in Colorectal Carcinoma

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Plabon Kumar Das, Farhadul Islam, Alfred K. Lam

Journal: CellsYear: 2020Citations: 218

Cancer stem cells (CSCs) are the main culprits involved in therapy resistance and disease recurrence in colorectal carcinoma (CRC). Results using cell culture, animal models and tissues from patients with CRC suggest the indispensable roles of colorectal CSCs in therapeutic failure. Conventional the...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Public human microbiome data are dominated by highly developed countries

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Richard J. Abdill, Elizabeth M. Adamowicz, Ran Blekhman

Journal: PLoS BiologyYear: 2022Citations: 214

The importance of sampling from globally representative populations has been well established in human genomics. In human microbiome research, however, we lack a full understanding of the global distribution of sampling in research studies. This information is crucial to better understand global pat...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Fish Disease Detection Using Image Based Machine Learning Technique in Aquaculture

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Md Shoaib Ahmed, Tanjim Taharat Aurpa, Md. Abul Kalam Azad

Journal: Journal of King Saud University - Computer and Information SciencesYear: 2021Citations: 213

Fish diseases in aquaculture constitute a significant hazard to nutriment security. Identification of infected fishes in aquaculture remains challenging to find out at the early stage due to the dearth of necessary infrastructure. The identification of infected fish timely is an obligatory step to t...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation

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Lorenzo de la Rica, Javier Rodríguez‐Ubreva, Mireia García, Abul Bashar Mir Md. Khademul Islam et al.

Journal: Genome biologyYear: 2013Citations: 213

BACKGROUND: DNA methylation is a key epigenetic mechanism for driving and stabilizing cell-fate decisions. Local deposition and removal of DNA methylation are tightly coupled with transcription factor binding, although the relationship varies with the specific differentiation process. Conversion of ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Nutritional Value and Medicinal Benefits of Pineapple

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Md. Farid Hossain

Journal: International Journal of Nutrition and Food SciencesYear: 2015Citations: 212

This paper discusses nutritional values and importance of pineapple in the health aspects. Thailand, Philippines, Mexico, Costa Rica, Brazil, China, Nigeria, Kenya, Indonesia, Hawaii, India, Bangladesh are the major pineapple producing countries. The demand of pineapple in the international market i...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Gut Microbial Succession Follows Acute Secretory Diarrhea in Humans

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Lawrence A. David, Ana A. Weil, Edward T. Ryan, Stephen B. Calderwood et al.

Journal: mBioYear: 2015Citations: 209

UNLABELLED: Disability after childhood diarrhea is an important burden on global productivity. Recent studies suggest that gut bacterial communities influence how humans recover from infectious diarrhea, but we still lack extensive data and mechanistic hypotheses for how these bacterial communities ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

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Arka Chakraborty, Saikat Mitra, Trina Ekawati Tallei, Abu Montakim Tareq et al.

Journal: LifeYear: 2021Citations: 208

Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It is most commonly used as an anti-inflammatory agent, though scientists have also discovered its potential as an an...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Recent advances and limitations of mTOR inhibitors in the treatment of cancer

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Eunüs S. Ali, Kangkana Mitra, Shamima Akter, Sarker Ramproshad et al.

Journal: Cancer Cell InternationalYear: 2022Citations: 207

The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR) signaling pathway is important in a variety of biological activities, including cellular proliferation, survival, metabolism, autophagy, and immunity. Abnormal PI3K-Akt-mTOR signalling activation can promote transformation ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Circular RNA <i>TLK1</i> Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP

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Fangfang Wu, Bing Han, Shusheng Wu, Li Yang et al.

Journal: Journal of NeuroscienceYear: 2019Citations: 205

Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in various CNS diseases. However, the potential role of circRNAs in ischemic stroke-associated neuronal injury remains largely unknown. Here, we investigated the important functions of circRNA TLK1 (circTLK1) in this...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Construction of an enzyme-free concatenated DNA circuit for signal amplification and intracellular imaging

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Huimin Wang, Chunxiao Li, Xiaoqing Liu, Xiang Zhou et al.

Journal: Chemical ScienceYear: 2018Citations: 203

A rationally and modularly engineered two-layered CHA–HCR circuit was constructed for amplified biosensing and bioimaging with high performance.

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes

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Siddhartha Dutta, Rima Shah, Shubha Singhal, Sudeshna Banerjee Dutta et al.

Journal: Drug Design Development and TherapyYear: 2023Citations: 201

Metformin has been designated as one of the most crucial first-line therapeutic agents in the management of type 2 diabetes mellitus. Primarily being an antihyperglycemic agent, metformin also has a plethora of pleiotropic effects on various systems and processes. It acts majorly by activating AMPK ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Oxidative post-translational modifications of cysteine residues in plant signal transduction

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Cezary Waszczak, Salma Akter, Silke Jacques, Jingjing Huang et al.

Journal: Journal of Experimental BotanyYear: 2015Citations: 199

In plants, fluctuation of the redox balance by altered levels of reactive oxygen species (ROS) can affect many aspects of cellular physiology. ROS homeostasis is governed by a diversified set of antioxidant systems. Perturbation of this homeostasis leads to transient or permanent changes in the redo...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor

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Md. Abdullahil Baque, Sang-Hyun Moh, Eunjung Lee, Jian‐Jiang Zhong et al.

Journal: Biotechnology AdvancesYear: 2011Citations: 198

The increasing global demand for biomass of medicinal plant resources reflects the issues and crisis created by diminishing renewable resources and increasing consumer populations. Moreover, diverse usage of plants and reduced land for cultivation in the world accelerated the deficiency of plant res...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System

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Md. Abdul Hannan, Raju Dash, Abdullah Al Mamun Sohag, Md. Nazmul Haque et al.

Journal: Frontiers in Molecular NeuroscienceYear: 2020Citations: 196

Oxidative stress (OS) plays a critical role in the pathophysiology of several brain-related disorders, including neurodegenerative diseases and ischemic stroke, which are the major causes of dementia. The Nrf2-ARE (nuclear factor erythroid 2-related factor 2/antioxidant responsive element antioxidan...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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