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Field: Molecular Medicine

Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

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Tanvir Mahtab Uddin, Arka Chakraborty, Ameer Khusro, BM Redwan Matin Zidan et al.

Journal: Journal of Infection and Public Health
Year: 2021
Citations: 1237

Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-molecular-weight bioactive agents have also been used for a variety of other medicinal applications. In the battle against microbes, antibiotics have certainly been a blessing to human civilization by savin...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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A Review on Antibiotic Resistance: Alarm Bells are Ringing

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Sojib Bin Zaman, Muhammed Awlad Hussain, Rachel Nye, Varshil Mehta et al.

Journal: CureusYear: 2017Citations: 857

Antibiotics are the 'wonder drugs' to combat microbes. For decades, multiple varieties of antibiotics have not only been used for therapeutic purposes but practiced prophylactically across other industries such as agriculture and animal husbandry. Uncertainty has arisen, as microbes have become resi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Cellulose-based hydrogel materials: chemistry, properties and their prospective applications

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S M Fijul Kabir, Partha Sikdar, Bazle Z. Haque, M. A. Rahman Bhuiyan et al.

Journal: Progress in BiomaterialsYear: 2018Citations: 553

Hydrogels based on cellulose comprising many organic biopolymers including cellulose, chitin, and chitosan are the hydrophilic material, which can absorb and retain a huge proportion of water in the interstitial sites of their structures. These polymers feature many amazing properties such as respon...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Progress in Alternative Strategies to Combat Antimicrobial Resistance: Focus on Antibiotics

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Jayaseelan Murugaiyan, P. Anand Kumar, G. Srinivasa Rao, Katia Iskandar et al.

Journal: AntibioticsYear: 2022Citations: 524

Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR), continues to evolve and spread beyond all boundaries. As a result, infectious diseases have become more challenging or even impossible to treat, leading to an increase in morbidity and mortality. Despite the failur...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Antimicrobial Resistance: A Growing Serious Threat for Global Public Health

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Md. Abdus Salam, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, Jogendra Singh Pawar et al.

Journal: Preprints.orgYear: 2023Citations: 495

Antibiotics are the most magnificent discovery of 20th century that have saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from increasing use and misuse of antibiotics over the years. The tr...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Metal complexes of curcumin – synthetic strategies, structures and medicinal applications

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Simon Wanninger, Volker Lorenz, Md Abdus Subhan, Frank T. Edelmann

Journal: Chemical Society ReviewsYear: 2015Citations: 422

This Tutorial Review presents an overview on the synthesis, characterization and applications of metal complexes containing curcumin (=1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) and its derivatives as ligands. Innovative synthetic strategies leading to soluble and crystallizable me...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Extended-Spectrum β-Lactamases (ESBL): Challenges and Opportunities

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Asmaul Husna, Md. Masudur Rahman, A. T. M. Badruzzaman, Mahmudul Hasan Sikder et al.

Journal: BiomedicinesYear: 2023Citations: 282

The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase producing Enterobacteriaceae (ESBL-E), poses a significant global health challenge as it frequently causes the failure of empirical antibiotic therapy, leading to morbidity and mortality. The E. coli- and K. pneumo...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Recent advances in the synthesis of smart hydrogels

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Partha Sikdar, Md Mazbah Uddin, Tanvir Mahady Dip, Shafiqul Islam et al.

Journal: Materials AdvancesYear: 2021Citations: 234

Understanding the surrounding atmosphere and reacting accordingly with a precise action are always fascinating features of a material.

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets

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Hitesh Chopra, Protity Shuvra Dey, Debashrita Das, Tanima Bhattacharya et al.

Journal: MoleculesYear: 2021Citations: 232

is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmaco...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Cellulose-Based Superabsorbent Hydrogels

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Md. Ibrahim H. Mondal

Journal: Polymers and polymeric compositesYear: 2019Citations: 219
Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA): a multinational prospective cohort study

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Andrew J. Stewardson, Kalisvar Marimuthu, Sharmila Sengupta, Arthur Allignol et al.

Journal: The Lancet Infectious DiseasesYear: 2019Citations: 217

BACKGROUND Low-income and middle-income countries (LMICs) are under-represented in reports on the burden of antimicrobial resistance. We aimed to quantify the clinical effect of carbapenem resistance on mortality and length of hospital stay among inpatients in LMICs with a bloodstream infection due ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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Potential Role of Curcumin and Its Nanoformulations to Treat Various Types of Cancers

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Md. Tanvir Kabir, Md. Habibur Rahman, Rokeya Akter, Tapan Behl et al.

Journal: BiomoleculesYear: 2021Citations: 204

Cancer is a major burden of disease globally. Each year, tens of millions of people are diagnosed with cancer worldwide, and more than half of the patients eventually die from it. Significant advances have been noticed in cancer treatment, but the mortality and incidence rates of cancers are still h...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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An Overview on Starch-Based Sustainable Hydrogels: Potential Applications and Aspects

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Md. Qamruzzaman, Firoz Ahmed, Md. Ibrahim H. Mondal

Journal: Journal of Polymers and the EnvironmentYear: 2021Citations: 197
Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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Antimicrobial Resistance, Virulence Factors and Genetic Diversity of Escherichia coli Isolates from Household Water Supply in Dhaka, Bangladesh

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Prabhat K. Talukdar, Md Mizanur Rahman, Mahdia Rahman, Ashikun Nabi et al.

Journal: PLoS ONEYear: 2013Citations: 187

BACKGROUND: Unsafe water supplies continue to raise public health concerns, especially in urban areas in low resource countries. To understand the extent of public health risk attributed to supply water in Dhaka city, Bangladesh, Escherichia coli isolated from tap water samples collected from differ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Ultrastretchable, Self-Healable Hydrogels Based on Dynamic Covalent Bonding and Triblock Copolymer Micellization

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Peng Wang, Guohua Deng, Lanying Zhou, Zhiyong Li et al.

Journal: ACS Macro LettersYear: 2017Citations: 180

Excellent mechanical properties and remarkable self-healing ability are difficult to unify in one hydrogel. We integrated acylhydrazone bonds and Pluronic F127 (PF127) micelle cross-linking, as two kinds of dynamic cross-links, in one system and developed hydrogels with superior stretchability, high...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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