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Field: Molecular Medicine

The Multifaceted Role of Curcumin in Advanced Nanocurcumin Form in the Treatment and Management of Chronic Disorders

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Priti Tagde, Pooja Tagde, Fahadul Islam, Sandeep Tagde et al.

Journal: Molecules 2021
Year:
Citations: 160

Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, antibacterial, and anticancer effects against various cancers, but has poor solubility and low bioavailability....

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Evaluation of antinociceptive, in-vivo & in-vitro anti-inflammatory activity of ethanolic extract of Curcuma zedoaria rhizome

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H. M. Arif Ullah, Sayera Zaman, Fatematuj Juhara, Lucky Akter et al.

Journal: BMC Complementary and Alternative MedicineYear: 2014Citations: 154

BACKGROUND: The present study was aimed to investigate the antinociceptive and anti-inflammatory activity of the Curcuma zedoaria (family Zingiberaceae) ethanolic rhizome extract in laboratory using both in vitro and in vivo methods so as to justify its traditional use in the above mentioned patholo...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Drug Delivery Strategies and Biomedical Significance of Hydrogels: Translational Considerations

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Neha Raina, Rakesh Pahwa, Jaydeep Bhattacharya, Alok Kumar Paul et al.

Journal: PharmaceuticsYear: 2022Citations: 143

Hydrogels are a promising and attractive option as polymeric gel networks, which have immensely fascinated researchers across the globe because of their outstanding characteristics such as elevated swellability, the permeability of oxygen at a high rate, good biocompatibility, easy loading, and drug...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Targeted therapies of curcumin focus on its therapeutic benefits in cancers and human health: Molecular signaling pathway-based approaches and future perspectives

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Md. Rezaul Islam, Abdur Rauf, Shopnil Akash, Sadiya Islam Trisha et al.

Journal: Biomedicine & PharmacotherapyYear: 2023Citations: 136

The curry powder spices turmeric (Curcuma longa L.), which contains curcumin (diferuloylmethane), an orange-yellow chemical. Polyphenols are the most commonly used sources of curcumin. It combats oxidative stress and inflammation in diseases, such as hyperlipidemia, metabolic syndrome, arthritis, an...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Antibiotic Resistance of Escherichia Coli Isolated From Poultry and Poultry Environment of Bangladesh

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Muhammad Ali

Journal: American Journal of Environmental SciencesYear: 2009Citations: 131

Problem statement: Increased emergence in microbial resistance to antibiotics is a growing problem in Bangladesh, a tropical country with a large agrarian population having limited medical facilities. Wide spread use of antimicrobials in poultry farming here is a concern of multi-drug microbial resi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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A framework for global surveillance of antibiotic resistance

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Hajo Grundmann, Keith P. Klugman, Timothy R. Walsh, Pilar Ramón-Pardo et al.

Journal: Drug Resistance UpdatesYear: 2011Citations: 127

The foreseen decline in antibiotic effectiveness explains the needs for data to inform the global public health agenda about the magnitude and evolution of antibiotic resistance as a serious threat to human health and development. Opportunistic bacterial pathogens are the cause of the majority of co...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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Isolation and molecular characterization of multidrug-resistant Escherichia coli from chicken meat

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Md. Masudur Rahman, Asmaul Husna, Hatem A. Elshabrawy, Jahangir Alam et al.

Journal: Scientific ReportsYear: 2020Citations: 126

Antibiotic-resistant Escherichia coli (E. coli) are common in retail poultry products. In this study, we aimed to isolate and characterize multidrug resistant (MDR) E. coli in raw chicken meat samples collected from poultry shops in Sylhet division, Bangladesh, as well as to determine correlation be...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications

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Bohan Yin, Monika Gosecka, Mahdi Bodaghi, Daniel Crespy et al.

Journal: Chemical Engineering JournalYear: 2024Citations: 110

Hydrogels have emerged in various biomedical applications, including tissue engineering and medical devices, due to their ability to imitate the natural extracellular matrix (ECM) of tissues. However, conventional static hydrogels lack the ability to dynamically respond to changes in their surroundi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Risk Factors and Outcomes Associated with Acquisition of Colistin-Resistant KPC-Producing <i>Klebsiella pneumoniae</i> : a Matched Case-Control Study

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Olympia Zarkotou, Spyros Pournaras, Evangelia Voulgari, Georgios Chrysos et al.

Journal: Journal of Clinical MicrobiologyYear: 2010Citations: 107

A matched 1:3 case-control study investigated factors predicting colistin-resistant versus colistin-susceptible KPC-producing Klebsiella pneumoniae acquisition and its impact on patient outcomes. Case patients were more often admitted from other institutions (P = 0.019) and had longer therapy with b...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic <i>Escherichia coli</i> (ExPEC) Lineages

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Sabiha Shaik, Amit Ranjan, Sumeet K. Tiwari, Arif Hussain et al.

Journal: mBioYear: 2017Citations: 102

ABSTRACT Escherichia coli sequence type 131 (ST131), a pandemic clone responsible for the high incidence of extraintestinal pathogenic E. coli (ExPEC) infections, has been known widely for its contribution to the worldwide dissemination of multidrug resistance. Although other ExPEC-associated and ex...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Polysaccharide-Based Hydrogels for Advanced Biomedical Engineering Applications

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Md. Mahamudul Hasan Rumon, Anwarul Azim Akib, Stephen Don Sarkar, Md. Abu Rayhan Khan et al.

Journal: ACS Polymers AuYear: 2024Citations: 98

In recent years, numerous applications of hydrogels using polysaccharides have evolved, benefiting from their widespread availability, excellent biodegradability, biocompatibility, and nonpoisonous nature. These natural polymers are typically sourced from renewable materials or from manufacturing pr...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Interaction chemistry of functional groups for natural biopolymer-based hydrogel design

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Mozammel Hoque, Md Masruck Alam, Sungrok Wang, Jahid Uz Zaman et al.

Journal: Materials Science and Engineering R ReportsYear: 2023Citations: 98
Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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Environmental Spread of New Delhi Metallo-β-Lactamase-1-Producing Multidrug-Resistant Bacteria in Dhaka, Bangladesh

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Mohammad Aminul Islam, Moydul Islam, Rashedul Hasan, Muhammed Iqbal Hossain et al.

Journal: Applied and Environmental MicrobiologyYear: 2017Citations: 97

ABSTRACT Resistance to carbapenem antibiotics through the production of New Delhi metallo-β-lactamase-1 (NDM-1) constitutes an emerging challenge in the treatment of bacterial infections. To monitor the possible source of the spread of these organisms in Dhaka, Bangladesh, we conducted a comparative...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Antimicrobial Drug–Resistant<i>Escherichia coli</i>in Wild Birds and Free-range Poultry, Bangladesh

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Badrul Hasan, Linus Sandegren, Åsa Melhus, Mirva Drobni et al.

Journal: Emerging infectious diseasesYear: 2012Citations: 97

Multidrug resistance was found in 22.7% of Escherichia coli isolates from bird samples in Bangladesh; 30% produced extended-spectrum β-lactamases, including clones of CTX-M genes among wild and domestic birds. Unrestricted use of antimicrobial drugs in feed for domestic birds and the spread of resis...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Risk of Transmission of Antimicrobial Resistant Escherichia coli from Commercial Broiler and Free-Range Retail Chicken in India

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Arif Hussain, Sabiha Shaik, Amit Ranjan, Nishant Nandanwar et al.

Journal: Frontiers in MicrobiologyYear: 2017Citations: 95

Multidrug-resistant Escherichia coli (E. coli) infections are a growing public health concern. This study analyzed the contamination of commercial poultry (broiler and free-range) with pathogenic and or multi-resistant E. coli in India. We analyzed 168 E. coli isolates from broiler and free-range re...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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