Richard K. Scher, Amir Tavakkol, Bárður Sigurgeirsson, Roderick J. Hay et al.
Until now, there has been no agreement on criteria defining resolution of onychomycosis. Most published reports use clinical and mycological cure, which comprises a completely normal-appearing nail plate, and negative nail culture and microscopy results, as the end point for defining success of ther...
Pietro Nenoff, Shyam B. Verma, Andreas Ebert, Anke Süß et al.
Chronic recalcitrant dermatophytoses, due to Trichophyton (T.) mentagrophytes Type VIII are on the rise in India and are noteworthy for their predominance. It would not be wrong to assume that travel and migration would be responsible for the spread of T. mentagrophytes Type VIII from India, with ma...
Jullie M. Sarmiento-Ramírez, Elena Abella‐Perez, Andrea D. Phillott, Jolene Sim et al.
Nascent fungal infections are currently considered as one of the main threats for biodiversity and ecosystem health, and have driven several animal species into critical risk of extinction. Sea turtles are one of the most endangered groups of animals and only seven species have survived to date. Her...
Ryan F. Donnelly, Paul A. McCarron, Julie M. Lightowler, A. David Woolfson
The in vitro penetration of 5-aminolevulinic acid (ALA) across human nail and into neonate porcine hoof when released from a novel bioadhesive patch containing 50 mg cm(-2) ALA is described. ALA is a naturally occurring precursor of the photosensitiser protoporphyrin IX (PpIX). Topical application o...
Avrom S. Caplan, Gabrielle C. Todd, YanChun Zhu, Michelle Sikora et al.
Importance: Trichophyton indotineae is an emerging dermatophyte causing outbreaks of extensive tinea infections often unresponsive to terbinafine. This species has been detected worldwide and in multiple US states, yet detailed US data on infections with T indotineae are sparse and could improve tre...
Paul A. McCarron, Ryan F. Donnelly, Agnieszka Zawiślak, A. David Woolfson et al.
An innovative bioadhesive patch intended primarily as a vulval drug delivery system and, specifically, as a means to deliver photosensitisers, or their prodrugs, for photodynamic purposes is described. The patch was formulated with a copolymer of methyl vinyl ether and maleic anhydride (PMVE/MA) as ...
Mohammed Saiful Islam Bhuiyan, Shyam B. Verma, Gina-Marie Illigner, Silke Uhrlaß et al.
Trichophyton (T.) mentagrophytes ITS genotype VIII, also known as Trichophyton indotineae, is a new species of the T. mentagrophytes/T. interdigitale complex and its first records, albeit under a different species name, are from the Indian subcontinent, Middle Eastern Asia, and West Asia. T. mentagr...
Aditya K. Gupta, Mesbah Talukder, Jessie Carviel, Elizabeth A. Cooper et al.
Antifungal resistance has become prevalent worldwide. Understanding the factors involved in spread of resistance allows the formulation of strategies to slow resistance development and likewise identify solutions for the treatment of highly recalcitrant fungal infections. To investigate the recent e...
Amjad Hossain, Bruno C. Sil, Fotis Iliopoulos, Rebecca Lever et al.
Terbinafine (TBF) is commonly used in the management of fungal infections of the skin because of its broad spectrum of activity. Currently, formulations containing the free base and salt form are available. However, there is only limited information in the literature about the physicochemical proper...
U. Rappo, Jeremy R. Beitler, Jason Faulhaber, Bahar Firoz et al.
U. Rappo, J.R. Beitler, J.R. Faulhaber, B. Firoz, J.S. Henning, K.M. Thomas, M. Maslow, D.S. Goldfarb, H.W. Horowitz. Expanding the horizons of histoplasmosis: disseminated histoplasmosis in a renal transplant patient after a trip to Bangladesh.Transpl Infect Dis 2010: 12: 155–160. All rights reserv...
Aditya K. Gupta, Tong Wang, Avantika Mann, Shruthi Polla Ravi et al.
INTRODUCTION: infections. This species is usually poorly responsive to terbinafine. AREAS COVERED: . Terbinafine has become less effective as a first-line agent attributed to mutations in the squalene epoxidase gene (Leu393Phe, Phe397Leu). Alternative therapies include itraconazole for a longer time...
SK Sarkar, A. K. M. Saiful Islam, KG Sen, ARS Ahmed
It is generally agreed that the pattern of skin diseases differs in different countries, and within various regions of a country depending on social, economic, racial and environmental factors. Many workers have reported various patterns of skin diseases in different countries. So far, no such repor...
Roberto Arenas, Gabriela Moreno‐Coutiño, Gustavo Reyes‐Terán
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Aditya K. Gupta, Avner Shemer, Vasiliki Economopoulos, Mesbah Talukder
Diabetes Mellitus (DM) is a significant global concern. Many diabetic patients will experience complications due to angiopathy, neuropathy, and immune dysfunction, namely diabetic foot ulcers (DFU) and diabetic foot infections (DFI), which can result in lower limb amputation and potentially death. T...