Rashidul Haque, Abu Syed Golam Faruque, P Hahn, David M. Lyerly et al.
The prevalence of infection by the invasive parasite Entamoeba histolytica and the noninvasive parasite Entamoeba dispar was determined in 2000 children in Bangladesh. Antigen detection identified more cases of E. histolytica-E. dispar infection than did culture or microscopy. Microscopic identifica...
Susana Vaz Nery, Amy J. Pickering, Ebba Abate, Abraham Asmare et al.
The transmission soil transmitted helminths (STH) occurs via ingestion of or contact with infective stages present in soil contaminated with human faeces. It follows therefore that efforts to reduce faecal contamination of the environment should help to reduce risk of parasite exposure and improveme...
Shurong Dong, Ya Yang, Yingjian Wang, Dongjian Yang et al.
BACKGROUND: Cryptosporidium is a protozoan parasite that can infect both humans and animals and cause cryptosporidiosis. We aimed to estimate the global prevalence of Cryptosporidium infection. METHODS: In this study, Web of Science, Medline and PubMed were searched for relative articles, published ...
Dinesh Mondal, Shri Prakash Singh, Narendra Kumar, Anand Joshi et al.
OBJECTIVE: We sought to estimate visceral leishmaniasis (VL) burden in Bangladesh, India, and Nepal and document care-seeking behaviour for VL to provide baseline information for monitoring the VL elimination program and identify options for improved case finding and management. DESIGN: A cross-sect...
Leo X. Liu, Peter F. Weller
Many different infections with protozoan and helminthic parasites are common global health problems. Several protozoa are responsible for opportunistic infections in patients with AIDS. The newly developed drug, albendazole, has a strong activity against many nematode and cestode parasites. In the c...
Sowmya Pattabhi, Jacqueline Whittle, Raodoh Mohamath, Sayda El‐Safi et al.
BACKGROUND: Visceral leishmaniasis (VL) is diagnosed by microscopic confirmation of the parasite in bone marrow, spleen or lymph node aspirates. These procedures are unsuitable for rapid diagnosis of VL in field settings. The development of rK39-based rapid diagnostic tests (RDT) revolutionized diag...
Zachary Silver, Saravanakumar Puthupalayam Kaliappan, Prasanna Samuel, Srinivasan Venugopal et al.
BACKGROUND: Soil-transmitted helminth (STH) infections are among the most prevalent neglected tropical diseases (NTD) worldwide. Since the publication of the WHO road map to combat NTD in 2012, there has been a renewed commitment to control STH. In this study, we analysed the geographical distributi...
Filip Meheus, Manica Balasegaram, Piero Olliaro, Shyam Sundar et al.
BACKGROUND: Visceral leishmaniasis is a systemic parasitic disease that is fatal unless treated. We assessed the cost and cost-effectiveness of alternative strategies for the treatment of visceral leishmaniasis in the Indian subcontinent. In particular we examined whether combination therapies are a...
Caryn Bern, Rashidul Haque, RAJIB CHOWDHURY, Mustakim Ali et al.
We examined the epidemiology of kala-azar and asymptomatic leishmanial infection measured by serologic and leishmanin skin test results in a Bangladeshi community. In a subset, we measured serum retinol, zinc and C-reactive protein (CRP). Kala-azar and seroconversion incidence were 15.6 and 63.1 per...
Gretchen Ehrenkaufer, Rashidul Haque, Jason A. Hackney, Daniel Eichinger et al.
Developmental switching between life-cycle stages is a common feature among many pathogenic organisms. The protozoan parasite Entamoeba histolytica converts between cysts (essential for disease transmission) and trophozoites (responsible for tissue invasion). Identification of genes involved in the ...
Ramon M. Eichenberger, Md Hasanuzzaman Talukder, Matthew A. Field, Phurpa Wangchuk et al.
ABSTRACT Whipworms are parasitic nematodes that live in the gut of more than 500 million people worldwide. Owing to the difficulty in obtaining parasite material, the mouse whipworm Trichuris muris has been extensively used as a model to study human whipworm infections. These nematodes secrete a mul...
Wasif Ali Khan, Jeffrey K. Griffiths, Michael L. Bennish
OBJECTIVE: To determine the clinical manifestations and outcome of shigellosis among children infected with different species of Shigella. METHODS: We identified all patients <15 years infected with Shigella admitted to the icddr, b Dhaka hospital during one year. Study staff reviewed admission reco...
Dinesh Mondal, Prakash Ghosh, Md Anik Ashfaq Khan, Faria Hossain et al.
BACKGROUND: Leishmania donovani (LD) is a protozoan parasite transmitted to humans from sand flies, which causes Visceral Leishmaniasis (VL). Currently, the diagnosis is based on presence of the anti-LD antibodies and clinical symptoms. Molecular diagnosis would require real-time PCR, which is not e...
Carol A. Gilchrist, Sarah E. Petri, Brittany N. Schneider, Daniel Reichman et al.
BACKGROUND: An estimated 1 million children die each year before their fifth birthday from diarrhea. Previous population-based surveys of pediatric diarrheal diseases have identified the protozoan parasite Entamoeba histolytica, the etiological agent of amebiasis, as one of the causes of moderate-to...