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Field: Pharmacological Effects of Natural Compounds

Prospect of biobased antiviral face mask to limit the coronavirus outbreak

Verified

Mohammad Asaduzzaman Chowdhury, Md. Bengir Ahmed Shuvho, Md. Abdus Shahid, Ashraful Haque et al.

Environmental Research
Journal:
Year: 2020
Citations: 106

The rapid spread of COVID-19 has led to nationwide lockdowns in many countries. The COVID-19 pandemic has played serious havoc on economic activities throughout the world. Researchers are immensely curious about how to give the best protection to people before a vaccine becomes available. The corona...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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The Dietary Flavonoid Kaempferol Mediates Anti‐Inflammatory Responses via the Src, Syk, IRAK1, and IRAK4 Molecular Targets

Verified

Shi Hyoung Kim, Jae Gwang Park, Jongsung Lee, Woo Seok Yang et al.

Journal: Mediators of InflammationYear: 2015Citations: 103

Even though a lot of reports have suggested the anti-inflammatory activity of kaempferol (KF) in macrophages, little is known about its exact anti-inflammatory mode of action and its immunopharmacological target molecules. In this study, we explored anti-inflammatory activity of KF in LPS-treated ma...

Health SciencesMedicineSurgeryOpen Access
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Risk factors for development of hemolytic uremic syndrome during shigellosis

Verified

Thomas Butler, M R Islam, Muhammad Abul Kalam Azad, Paul K. Jones

Journal: The Journal of PediatricsYear: 1987Citations: 99
Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinology
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<i>Zingiber officinale</i>: A Potential Plant against Rheumatoid Arthritis

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Abdullah Al Nahain, Rownak Jahan, Mohammed Rahmatullah

Journal: ArthritisYear: 2014Citations: 96

Rheumatoid arthritis (RA) is an autoimmune disease particularly affecting elderly people which leads to massive bone destruction with consequent inflammation, pain, and debility. Allopathic medicine can provide only symptomatic relief. However, Zingiber officinale is a plant belonging to the Zingibe...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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Antidiarrhoeal activity of the ethanol extract of Paederia foetida Linn. (Rubiaceae)

Verified

Sabrina Afroz, M Alamgir, Majid Khan, S. Jabbar et al.

Journal: Journal of EthnopharmacologyYear: 2005Citations: 94

Paederia foetida L. is used as a remedy for diarrhoea and dysentery in Asia, but has not been investigated for its antidiarrhoeal properties. Antidiarrhoeal activity of 90% ethanol extract of Paederia foetida was investigated in this study using castor oil and magnesium sulphate-induced diarrhoea mo...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacology
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Choline and amino acid based biocompatible ionic liquid mediated transdermal delivery of the sparingly soluble drug acyclovir

Verified

Rafiqul Islam, Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara et al.

Journal: International Journal of PharmaceuticsYear: 2020Citations: 91

Transdermal delivery of drugs is more challenging for drugs that are insoluble or sparingly soluble in water and most organic solvents. To overcome this problem, ionic liquid (IL)-mediated ternary systems have been suggested as potential drug carriers. Here, we report potent ternary (IL-EtOH-IPM) sy...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmaceutical Science
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Hericium erinaceus (Bull.: Fr) Pers. cultivated under tropical conditions: isolation of hericenones and demonstration of NGF-mediated neurite outgrowth in PC12 cells via MEK/ERK and PI3K-Akt signaling pathways

Verified

Chia‐Wei Phan, Guan-Serm Lee, Sok Lai Hong, Yuin-Teng Wong et al.

Journal: Food & FunctionYear: 2014Citations: 91

Hericium erinaceus (Bull.: Fr.) Pers. is an edible and medicinal mushroom used traditionally to improve memory. In this study, we investigated the neuritogenic effects of hericenones isolated from H. erinaceus and the mechanisms of action involved. H. erinaceus was cultivated and the secondary metab...

Health SciencesMedicinePharmacologyOpen Access
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Naringin and Naringenin Polyphenols in Neurological Diseases: Understandings from a Therapeutic Viewpoint

Verified

Talha Bin Emran, Fahadul Islam, Nikhil Nath, Hriday Sutradhar et al.

Journal: LifeYear: 2022Citations: 79

The glycosides of two flavonoids, naringin and naringenin, are found in various citrus fruits, bergamots, tomatoes, and other fruits. These phytochemicals are associated with multiple biological functions, including neuroprotective, antioxidant, anticancer, antiviral, antibacterial, anti-inflammator...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Evaluation of antidiarrhoeal activity Rumex maritimus root

Verified

Abu Shara Shamsur Rouf, Mohammad Saiful Islam, Md. Ashib Rahman

Journal: Journal of EthnopharmacologyYear: 2003Citations: 77

The partitioned n-hexane, ethylacetate and residual methanol extracts of the root of Rumex maritimus were evaluated for antidiarrhoeal activity in mice using castor oil and serotonin induced diarrhoea and also charcoal motility test at 50, 100 and 200 mg/kg body weight dose. Among these, the methano...

Life SciencesAgricultural and Biological SciencesPlant Science
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Molecular pharmacology and therapeutic advances of the pentacyclic triterpene lupeol

Verified

Abdullah Al Mamun Sohag, Md. Tahmeed Hossain, Md. Arifur Rahaman, Papia Rahman et al.

Journal: PhytomedicineYear: 2022Citations: 73

BACKGROUND Plant triterpenoids are major sources of nutraceuticals that provide many health benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in many fruits and vegetables, which is highly investigated for its pharmacological effect and benefit to human health...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Cold stress improves the production of artemisinin depending on the increase in endogenous jasmonate

Verified

Wanhong Liu, Huanyan Wang, Yu‐Pei Chen, Shunqin Zhu et al.

Journal: Biotechnology and Applied BiochemistryYear: 2016Citations: 73

Previous publications reported that the artemisinin level was increased in Artemisia annua following a night-frost period. However, the molecular mechanism was not clear. In this study, we found that exogenous jasmonate (JA) effectively enhanced the freezing tolerance of A. annua. The JA biosyntheti...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Probiotics and Amelioration of Rheumatoid Arthritis: Significant Roles of Lactobacillus casei and Lactobacillus acidophilus

Verified

Alok Kumar Paul, Anita Paul, Rownak Jahan, Khoshnur Jannat et al.

Journal: MicroorganismsYear: 2021Citations: 67

Rheumatoid arthritis is a chronic autoimmune disorder that can lead to disability conditions with swollen joints, pain, stiffness, cartilage degradation, and osteoporosis. Genetic, epigenetic, sex-specific factors, smoking, air pollution, food, oral hygiene, periodontitis, Prevotella, and imbalance ...

Life SciencesAgricultural and Biological SciencesFood ScienceOpen Access
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Volatile compounds of black cumin (Nigella sativa L.) seeds cultivated in Bangladesh and India

Verified

Yearul Kabir, Yoko Akasaka-Hashimoto, Kikue Kubota, Michio Komai

Journal: HeliyonYear: 2020Citations: 67

L. seeds from Bangladesh and India.

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Regulation of JAK2/STAT3 and NF-κB signal transduction pathways; Veronica polita alleviates dextran sulfate sodium-induced murine colitis

Verified

Md Rashedunnabi Akanda, Hyeon‐Hwa Nam, Weishun Tian, Anowarul Islam et al.

Journal: Biomedicine & PharmacotherapyYear: 2018Citations: 67

Ulcerative colitis (UC) is a major inflammatory bowel disease (IBD) has become a worldwide emergent disease. Veronica polita (VP) is a medicinal herb that has strong antioxidant and anti-inflammatory properties. In the present study, we studied the protective effect of VP on dextran sulfate sodium (...

Life SciencesBiochemistry, Genetics and Molecular BiologyGenetics
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Modulation of cell signaling pathways by Phyllanthus amarus and its major constituents: potential role in the prevention and treatment of inflammation and cancer

Verified

Hemavathy Harikrishnan, Ibrahim Jantan, Akilandeshwari Alagan, Md. Areeful Haque

Journal: InflammopharmacologyYear: 2019Citations: 62

The causal and functional connection between inflammation and cancer has become a subject of much research interest. Modulation of cell signaling pathways, such as those involving mitogen activated protein kinases (MAPKs), nuclear factor kappa β (NF-κB), phosphatidylinositol 3-kinase and protein kin...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacology
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