Mohammad Shoeb
Cancer is a major public health burden in both developed and developing countries. Plant derived agents are being used for the treatment of cancer. Several anticancer agents including taxol, vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, and etoposide derived from ...
Zidan Khan, Nikhil Nath, Abdur Rauf, Talha Bin Emran et al.
Currently, available therapeutic medications are both costly as well as not entirely promising in terms of potency. So, new candidates from natural resources are of research interest to find new alternative therapeutics. A well-known combination is a β-sitosterol, a plant-derived nutrient with antic...
Md. Rezaul Islam, Fahadul Islam, Mohamed H. Nafady, Muniya Akter et al.
Breast cancer (BrCa) is the most common malignancy in women and the second most significant cause of death from cancer. BrCa is one of the most challenging malignancies to treat, and it accounts for a large percentage of cancer-related deaths. The number of cases requiring more effective BrCa therap...
Shaikh Jamal Uddin, Lutfun Nahar, Jamil A. Shilpi, Mohammad Shoeb et al.
Abstract Xylocarpus granatum J. König (Meliaceae), commonly known as ‘dhundul’, is a Bangladeshi mangrove tree, and well distributed in a number of other countries of south‐east Asia, Australia and east Africa. Traditionally, X. granatum has been used as an astringent and febrifuge, and also for the...
Shaikh Jamal Uddin, Jamil A. Shilpi, Saidul Alam, M Alamgir et al.
The methanol (MeOH) extract of the barks of Xylocarpus moluccensis, and different fractions of this extract were studied for antidiarrhoeal activity using castor oil- and magnesium sulphate-induced diarrhoea models in mice. At the doses of 250 and 500 mg/kg, the MeOH extract showed significant antid...
Abdur Rauf, Mohammad Ali Shariati, Muhammad Imran, Kashif Bashir et al.
Though the incidence of several cancers in Western societies is regulated wisely, some cancers such as breast, lung, and colorectal cancer are currently rising in many low- and middle-income countries due to increased risk factors triggered by societal and development problems. Surgery, chemotherapy...
Mohammad Amzad Hossain, Zhari Ismail, Atiqur Rahman, Sun Chul Kang
The hydrodistilled essential leaves and stems oils of Orthosiphon stamineus Benth were analysed by GC-MS/MS. Sixty nine compounds representing 97.6 and 97.4% of the total leaves and stems oils, respectively were identified, of which β-caryophyllene (24.0 and 35.1%), α-humulene (14.2 and 18.4%), β-el...
Osman Goni, Mohammad Forhad Khan, Md. Masudur Rahman, Md. Zahid Hasan et al.
ETHNOPHARMACOLOGICAL RELEVANCE Aglaonema hookerianum Schott is an ethnomedicinally important plant used to treat a variety of diseases, including sexual and depression-like disorders. However, the scientific basis underlying the aforesaid properties have not been well justified. AIM OF THE STUDY The...
Rumpa Bhowmick, Md Shahid Sarwar, Syed Masudur Rahman Dewan, Abhijit Das et al.
BACKGROUND: The study was conducted to evaluate the in vitro thrombolytic activity, and in vivo analgesic, anti-inflammatory and antipyretic potentials of different hydrocarbon soluble extracts of Litsea glutinosa leaves for the first time widely used in the folkloric treatments in Bangladesh. This ...
Sherine George, Siddharth V Bhalerao, Erich A. Lidstone, Irfan Ahmad et al.
BACKGROUND: There has been a long standing interest in the identification of medicinal plants and derived natural products for developing cancer therapeutics. Our study focuses upon pancreatic cancer, due to its high mortality rate, that is attributed in part to the lack of an effective chemotherape...
Md Imdadul H. Khan, Md. Hossain Sohrab, Satyajit Roy Rony, Fakir Shahidullah Tareq et al.
OBJECTIVE: (L.) Benth. ex Kurz. (Fam: Apocyanaceae). MATERIALS AND METHODS: C NMR and mass spectroscopic data. The cytotoxicity was determined by WST-1 assay and brine shrimp lethality bioassay, while antibacterial activity was assessed by disc diffusion method. RESULTS: with an average zone of inhi...
Amit Roy, Aritra Simlai
This review represents the studies performed on some beneficial mangrove plants such as Ceriops decandra, Xylocarpus granatum, Xylocarpus moluccensis, Excoecaria agallocha, Sarcolobus globosus, Sonneratia caseolaris and Acanthus ilicifolius from the Sundarban estuary spanning India and Bangladesh wi...
Atiqur Rahman, Shah Alam Siddiqui, Rekha Jakhar, Kang Sun
We examined the anticancer effects of limonin and imperatorin on various human cancer cells by MTT assay, and the results showed that imperatorin inhibited the cell growth of SNU 449 (liver cancer) and HCT-15 (colon cancer) cells in a dose-dependent manner, while limonin had less effect. Exposure of...
Md Ashraful Alam, Abdullah Al Arif Jahan, Md. Sazzadul Bari, Labony Khandokar et al.
The genus Allium comprises of at least 918 species; the majority grown for dietary and medicinal purposes. This review describes the traditional uses, phytoconstituents, anti-inflammatory and anticancer activity, and safety profile of six main species, namely Allium sativum L. (garlic), Allium cepa ...
M. Mukhlesur Rahman, Shahnaj Parvin, Mohammad Rashedul Haque, Md. Ekramul Islam et al.
Annotemoyin-1, Annotemoyin-2, squamocin and cholesteryl glucopyranoside were isolated from the seeds of Annona squamosa. These compounds and plant extracts showed remarkable antimicrobial and cytotoxic activities.