Robert Howard, Rupert McShane, James Lindesay, Craig Ritchie et al.
BACKGROUND: Clinical trials have shown the benefits of cholinesterase inhibitors for the treatment of mild-to-moderate Alzheimer's disease. It is not known whether treatment benefits continue after the progression to moderate-to-severe disease. METHODS: We assigned 295 community-dwelling patients wh...
Olivia Anna Skrobot, Sandra E. Black, Christopher Chen, Charles DeCarli et al.
INTRODUCTION: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vasc...
Wei Bai, Pan Chen, Hong Cai, Qinge Zhang et al.
BACKGROUND: Mild cognitive impairment (MCI) is the preclinical and transitional stage between healthy ageing and dementia that may be a potential 'target' for interventions designed to delay progression to dementia. In this systematic review and meta-analysis, we assessed the prevalence of MCI world...
Rose McCabe, Stefan Priebe
BACKGROUND: Explanatory models of illness may differ between ethnic groups and influence treatment satisfaction and compliance. AIMS: To compare explanatory models among people with schizophrenia from four cultural backgrounds and explore their relationship with clinical and psychological characteri...
Jacob Bornstein, Andrew T. Goldstein, Colleen K. Stockdale, Sophie Bergeron et al.
INTRODUCTION: In 2014, the Executive Council of the International Society for the Study of Vulvovaginal Disease (ISSVD), the Boards of Directors of the International Society for the Study of Women's Sexual Health (ISSWSH), and the International Pelvic Pain Society (IPPS) acknowledged the need to rev...
Lawrence Leeman, Rebecca G. Rogers
In Brief Pregnancy and childbirth bring many changes to the health and well-being of new mothers. Postpartum sexual health is a common concern that is often not discussed during prenatal or postpartum care and has received little attention from either clinicians or researchers. In this article, we r...
Iñigo Sáenz de Tejada, Javier Angulo, Selim Cellek, Néstor F. González-Cadavid et al.
INTRODUCTION: Multiple regulatory systems are involved in normal erectile function. Disruption of psychological, neurological, hormonal, vascular, and cavernosal factors, individually, or in combination, can induced erectile dysfunction (ED). The contribution of neurogenic, vascular, and cavernosal ...
Gulam Khandaker, Mohammad Muhit, Tasneem Karim, Hayley Smithers‐Sheedy et al.
AIM: To examine the prevalence, clinical characteristics, and risk factors of cerebral palsy (CP) in children in Bangladesh. METHOD: The Bangladesh CP Register is an ongoing population-based surveillance database of children with CP from a geographically defined area in Bangladesh. Cases were define...
Richard E. Straub, C J MacLean, F. Anthony O’Neill, Dermot Walsh et al.
In our genome scan for schizophrenia genes in 265 Irish pedigrees, marker D5S818 in 5q22 produced the second best result of the first 223 markers tested (P = 0.002). We then tested an additional 13 markers and the evidence suggests the presence of a vulnerability locus for schizophrenia in region 5q...
James B. Kirkbride, Dave Barker, Fiona Cowden, Rebekah Stamps et al.
BACKGROUND: Consistent observation of raised rates of psychoses among Black and minority ethnic (BME) groups may possibly be explained by their lower socio-economic status. AIMS: To test whether risk for psychoses remained elevated in BME populations compared with the White British, after adjustment...
Siti Maisarah Mattap, Devi Mohan, Andrea McGrattan, Pascale Allotey et al.
INTRODUCTION: More than two-thirds of people with dementia live in low- and middle-income countries (LMICs), resulting in a significant economic burden in these settings. In this systematic review, we consolidate the existing evidence on the cost of dementia in LMICs. METHODS: Six databases were sea...
Morshedul Bari Antor, Ashfaq Jamil, Maliha Mamtaz, Mohammad Monirujjaman Khan et al.
Alzheimer's disease has been one of the major concerns recently. Around 45 million people are suffering from this disease. Alzheimer's is a degenerative brain disease with an unspecified cause and pathogenesis which primarily affects older people. The main cause of Alzheimer's disease is Dementia, w...
Israt Jahan, Mohammad Muhit, Denny Hardianto, Francis Laryea et al.
AIM: To describe the epidemiology of cerebral palsy (CP) in children from low- and middle-income countries (LMICs) using data from the Global Low- and Middle-Income Country CP register (GLM-CPR). METHOD: The GLM-CPR is a multi-country initiative that combines and compares data from children with CP ...
Anne Duffy, Sarah Goodday, Charles Keown‐Stoneman, Paul Grof
OBJECTIVE: The authors sought to describe the emergent course of bipolar disorder in offspring of affected parents subgrouped by parental response to lithium prophylaxis. METHODS: Parent bipolar disorder was confirmed by the best-estimate procedure and lithium response by research protocol. High-ris...
Medhia Afzal, Najma Siddiqi, Sheikh Bilal Ahmad, Nida Afsheen et al.
Aims: 1) To determine the pooled prevalence of overweight and obesity in people with severe mental illness (SMI), overall and by type of SMI, geographical region, and year of data collection; and 2) to assess the likelihood of overweight and obesity, in people with SMI compared with the general popu...