Tommaso Falcone, Rebecca Flyckt
Endometriosis is a common and challenging condition of reproductive-aged women that carries a high individual and societal cost. The many molecular dissimilarities between endometriosis lesions and eutopic endometrium create difficulties in the development of new drug therapies and treatments. Surge...
Rebecca C. Miller, Eleanor Brindle, Darryl J. Holman, Jane B. Shofer et al.
BACKGROUND: Specific gravity (SG) may perform as well as creatinine (CR) correction for adjusting urinary hormone concentrations, as well as offer some advantages. We compared the two methods and applied them to US and Bangladeshi specimens to evaluate their use in different populations. METHODS: Pe...
Ciara Hughes, Sharon Lewis, Valerie J. McKelvey‐Martin, W. Thompson
The integrity of sperm DNA is crucial for the maintenance of genetic health. A major source of damage is reactive oxygen species (ROS) generation; therefore, antioxidants may afford protection to sperm DNA. The objectives of the study were, first, to measure the effects of antioxidant supplementatio...
Paul Hoskins, Elizabeth A. Eisenhauer, Sandra Beare, Manas Pratim Roy et al.
PURPOSE: As topotecan is S-phase-specific, its efficacy is likely schedule-dependent. Therefore, a randomized study using a "pick the winner" design was undertaken to compare two schedules in patients with recurrent ovarian cancer. PATIENTS AND METHODS: Patients with recurrent epithelial ovarian can...
Subrato Bharati, Prajoy Podder, M. Rubaiyat Hossain Mondal
This paper focuses on the data-driven diagnosis of polycystic ovary syndrome (PCOS) in women. For this, machine learning algorithms are applied to a dataset freely available in Kaggle repository. This dataset has 43 attributes of 541 women, among which 177 are patients of PCOS disease. Firstly, univ...
Sayma Alam Suha, Muhammad Nazrul Islam
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinological abnormality and one of the primary causes of anovulatory infertility in women globally. The detection of multiple cysts using ovary ultrasonograpgy (USG) scans is one of the most reliable approach for making an accurate diagnosi...
Mohammad Bozlur Rahman, Leen Vandaele, Tom Rijsselaere, Dominiek Maes et al.
The objectives of this study were to identify the stages of spermatogenesis susceptible to elevated testicular temperature in terms of sperm motility, viability, morphology, chromatin protamination and nuclear shape. The latter two valuable parameters are not included in routine semen analysis. Scro...
Zhendong Zhu, Tomoko Kawai, Takashi Umehara, S. A. Masudul Hoque et al.
Mitochondrial oxidative phosphorylation (OXPHOS) is essential for ATP production to maintain sperm linear motility during migration from the uterus to the oviduct. However, ROS are generated as by-products of OXPHOS, causing stress and damaging the sperm quality. This study aimed to clarify the ROS ...
Md Bayejid Hosen, Md. Rakibul Islam, Firoza Begum, Yearul Kabir et al.
BACKGROUND: Sperm DNA damage is an important factor in the etiology of male infertility. OBJECTIVE: The aim of the study was to evaluate the association of oxidative stress induced sperm DNA damage with the pathogenesis of male infertility. MATERIALS AND METHODS: The study comprised a total of 66 su...
Susan Greenhalgh, W. Penn Handwerker
The politics of reproduction - a window on social change, W.Penn Handwerker the politics of reproductive biology - exclusionary policies in the United States, Rose Jones the politics of obstetric care - the Inuit experience, John O'Neill and Patricia A.Kaufert the politics of birth - cultural dimens...
Yvonne Kelly, Afshin Zilanawala, Amanda Sacker, Robert A. Hiatt et al.
OBJECTIVE: Early puberty in girls is linked to some adverse outcomes in adolescence and mid-life. We address two research questions: (1) Are socioeconomic circumstances and ethnicity associated with early onset puberty? (2) Are adiposity and/or psychosocial stress associated with observed associatio...
Luke Simon, Sheena Lewis
Sperm progressive motility has been reported to be one of the key factors influencing in vitro fertilization rates. However, recent studies have shown that sperm DNA fragmentation is a more robust predictor of assisted reproductive outcomes including reduced fertilization rates, embryo quality, and ...
Mosammat Rashida Begum, Jannatul Ferdous, Anowara Begum, Ehsan Quadir
Objective To compare the effectiveness of letrozole and clomiphene citrate (CC) in induction of ovulation in polycystic ovary syndrome (PCOS). Design Prospective, randomized, not blinded, controlled trial. Setting A tertiary level infertility care center. Patient(s) Sixty-four anovulatory patients w...
Evelyne Crabbé, Greta Verheyen, S. Silber, Herman Tournaye et al.
Recovery of testicular spermatozoa from azoospermic patients with testicular failure, followed by intracytoplasmic sperm injection (ICSI) is a recent advance in the treatment of male infertility. In most cases, free spermatozoa are recovered from testicular tissue after mechanical mincing of multipl...
Salima Akter, Md. Ataur Rahman, Mohammad Nazmul Hasan, Hajara Akhter et al.
Aggressive and recurrent gynecological cancers are associated with worse prognosis and a lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in advanced stages, when drug resistance, angiogenesis, relapse, and metastasis impact survival outcomes. Currently, surgi...