Terry Thomas, Kay R. Plymat, J Blannin, T W Meade
The prevalence of urinary incontinence was investigated by determining the number of incontinent patients under the care of various health and social service agencies in two London boroughs and by a postal survey of the 22 430 people aged 5 years and over on the practice lists of 12 general practiti...
Md Shaifur Rahman, Naznin Akhtar, Hossen Mohammad Jamil, Rajat Suvra Banik et al.
Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcom...
Hannah Blencowe, Simon Cousens, B. Modell, Joy E Lawn
BACKGROUND: Neural tube defects (NTDs) remain an important, preventable cause of mortality and morbidity. High-income countries have reported large reductions in NTDs associated with folic acid supplementation or fortification. The burden of NTDs in low-income countries and the effectiveness of foli...
Emily R. Smith, Anuraj H. Shankar, Lee Wu, Said Aboud et al.
BACKGROUND: Micronutrient deficiencies are common among women in low-income and middle-income countries. Data from randomised trials suggest that maternal multiple micronutrient supplementation decreases the risk of low birthweight and potentially improves other infant health outcomes. However, hete...
A. Młynek, Markus Magerl, M. Hanna, Stefan K. Lhachimi et al.
BACKGROUND: Chronic urticaria (CU) is a common skin disorder that causes a substantial burden on patients' quality-of-life (QoL). The aim of this work was to generate and validate a German version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q(2)oL) and to provide reference assessments...
Shi Wu Wen, Xi-Kuan Chen, Marc Rodger, Ruth Rennicks White et al.
Objective The objective of the study was to evaluate the association between folic acid supplementation in early second trimester and the risk of developing preeclampsia. Study design We carried out a prospective cohort study between October 2002-December 2005. We recruited women who had their prena...
Britt Elin Øiestad, Carsten Bogh Juhl, Adam G Culvenor, Bjørnar Berg et al.
OBJECTIVE: To update a systematic review on the association between knee extensor muscle weakness and the risk of incident knee osteoarthritis in women and men. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Systematic searches in PubMed, EMBASE, SPORTDiscus, CINAHL, AMED and CENTRAL in ...
Silvia Stacchiotti, Elena Tamborini, Salvatore Lo Vullo, Fabio Bozzi et al.
Background To report on a prospective, investigator-driven, phase II study on lapatinib in epidermal growth factor receptor (EGFR)-positive advanced chordoma patients. Patients and methods From December 2009 to January 2012, 18 advanced progressing chordoma patients entered this study (median age: 6...
Syed Atiqul Haq, Fereydoun Davatchi
This paper examines and summarizes data on knee osteoarthritis (AO) in Community Oriented Program For Control Of Rheumatic Disorders (COPCORD) publications. A literature search was made through PubMed, Google, Proceedings of Asia-Pacific League of Associations for Rheumatology (APLAR) congresses, an...
David F. Kroon, M. Louise Lawson, Craig S. Derkay, Karen K. Hoffmann et al.
OBJECTIVE: The study goal was to demonstrate the prevalence and severity of external auditory exostoses (EAEs) in a population of surfers and to examine the relationship between these lesions and the length of time surfed as well as water temperature in which the swimmers surfed. It was hypothesized...
R. C. L. FENELEY, Angela Shepherd, P. H. POWELL, Janet Blannin
The prevalence of recognised urinary incontinence in a community was found to be 1%; the prevalence of unrecognised incontinence was 3.3% in men and 8% in women in a group practice of 7000 patients. The approach to investigation and management of urinary incontinence in a urodynamic unit and the sta...
Md Asiful Islam, Shahad Saif Khandker, Przemysław Kotyla, Rosline Hassan
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organ involvement, including the skin, joints, kidneys, lungs, central nervous system and the haematopoietic system, with a large number of complications. Despite years of study, the etiology of SLE remains unclear...
Mary V. Gamble, Habibul Ahsan, Xinhua Liu, Pam Factor‐Litvak et al.
Background Indian Asian men residing in the United Kingdom have a higher prevalence of hyperhomocysteinemia than do their European counterparts. This has been largely attributed to dietary deficiencies in cobalamin associated with vegetarianism among these Indian Asians. Objective We aimed to ascert...
Oriol Morales‐Ibanez, Marlene Domínguez, Sung Hwan Ki, Miguel Marcos et al.
UNLABELLED: We identified, in the transcriptome analysis of patients with alcoholic hepatitis (AH), osteopontin (OPN) as one of the most up-regulated genes. Here, we used a translational approach to investigate its pathogenic role. OPN hepatic gene expression was quantified in patients with AH and o...
Yi Zhao, Huixin Li, Yu Luo, Jia-Gen Cui et al.
Di (2-ethylhexyl) phthalate (DEHP) is a hazardous chemical which is used as a plasticizer in the plastic products. Lycopene (LYC) is a carotenoid that has protective roles against cellular damage in different organs. The present study sought to explore the role of the interaction between mitophagy a...