Alan Kim Johnson, Paul M. Gross
Circumventricular organs (CVOs), small structures bordering the ventricular spaces in the midline of the brain, have common morphological and endocrine-like characteristics that distinguish them from the rest of the nervous system. Among their unique features are cellular contacts with two fluid pha...
Muhammad Chanchal Azad, Kristin Fraser, Nahid Rumana, Ahmad Faris Abdullah et al.
Medical students carry a large academic load which could potentially contribute to poor sleep quality above and beyond that already experienced by modern society. In this global literature review of the medical students' sleep experience, we find that poor sleep is not only common among medical stud...
Ahnaf Rashik Hassan, Abdülhamit Subaşı
Tetsuya Shiuchi, Mohammad Shahidul Haque, Shiki Okamoto, Tsuyoshi Inoue et al.
Hypothalamic neurons containing orexin (hypocretin) are activated during motivated behaviors and active waking. We show that injection of orexin-A into the ventromedial hypothalamus (VMH) of mice or rats increased glucose uptake and promoted insulin-induced glucose uptake and glycogen synthesis in s...
Md. Sahab Uddin, Devesh Tewari, Abdullah Al Mamun, Md. Tanvir Kabir et al.
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the most common type of dementia. Along with progressive cognitive impairment, dysfunction of the circadian rhythms also play a pivotal role in the progression of AD. A mutual relationship among circadian rhythms, sl...
Ahnaf Rashik Hassan, Mohammed Imamul Hassan Bhuiyan
Israt Z. Shahid, Ahmed A. Rahman, Paul M. Pilowsky
BACKGROUND AND PURPOSE: The rostral ventrolateral medulla (RVLM) maintains sympathetic nerve activity (SNA), and integrates adaptive reflexes. Orexin A-immunoreactive neurones in the lateral hypothalamus project to the RVLM. Microinjection of orexin A into RVLM increases blood pressure and heart rat...
IZ Shahid, AA Rahman, Paul M. Pilowsky
BACKGROUND: Intrathecal (i.t.) injection of orexin A (OX-A) increases blood pressure and heart rate (HR), but the effects of OX-A on sympathetic and phrenic, nerve activity, and the baroreflex(es), somato-sympathetic and hypoxic chemoreflex(es) are unknown. EXPERIMENTAL APPROACH: Urethane-anaestheti...
Md Belal Bin Heyat, Dakun Lai, Kaishun Wu, Faijan Akhtar et al.
Insomnia is well-known as trouble in sleeping and enormously influences human life due to the shortage of sleep. Reactive Oxygen Species (ROS) accrue in neurons during the waking state, and sleep has a defensive role against oxidative damage and dissipates ROS in the brain. In contrast, insomnia is ...
Sayaka Kozono, Takashi Matsuyama, Kamal Krishna Biwasa, Koichi Kawahara et al.
Endocannabinoids including anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are important lipid mediators for immunosuppressive effects and for appropriate homeostasis via their G-protein-coupled cannabinoid (CB) receptors in mammalian organs and tissues, and may be involved in wound healing in so...
Md. Farhad Hossain, Ni Wang, Ruijun Chen, Siwen Li et al.
Melatonin (MLT) is a neurohormone that is regulated by the circadian clock and plays multifunctional roles in numerous neurodegenerative disorders, such as Alzheimer's disease (AD). Alzheimer's disease is the most common form of dementia and is associated with the degradation of axons and synapses r...
Noemi Tesler, Miriam Gerstenberg, Reto Huber
PURPOSE OF REVIEW: Sleep undergoes major changes during development. Its relationship to the complex process of maturation in health and disease has recently received increased attention. This review aims to highlight the recent literature examining the interplay of altered sleep, brain development ...
Marc Schmid, Manuel Murbach, Caroline Lustenberger, Micheline Maire et al.
Studies have repeatedly shown that electroencephalographic power during sleep is enhanced in the spindle frequency range following radio frequency electromagnetic field exposures pulse-modulated with fundamental frequency components of 2, 8, 14 or 217 Hz and combinations of these. However, signals u...
Jingting Kong, Lv Zhou, Xiaoli Li, Qingguo Ren
Sleep disorders frequently result in poor memory, attention deficits, as well as a worse prognosis for neurodegenerative changes, such as Alzheimer's disease. The purpose of this study is to investigate the impact of sleep disorders on cognition. We screened four databases for all meta-analyses and ...
Raju Dash, Md. Chayan Ali, Israt Jahan, Yeasmin Akter Munni et al.
The aberrant accumulation of disease-specific protein aggregates accompanying cognitive decline is a pathological hallmark of age-associated neurological disorders, also termed as proteinopathies, including Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis...