Anne Polikeit, Lutz P. Nolte, Stephen J. Ferguson
STUDY DESIGN: The effect of cement augmentation on an osteoporotic lumbar functional spinal unit was investigated using finite-element analysis. OBJECTIVE: To evaluate the influence of cement augmentation on load transfer, stresses, and strains. SUMMARY OF BACKGROUND DATA: Osteoporosis is the most f...
Ricardo Vigatto, Neusa Maria Costa Alexandre, Heleno Rodrigues Corrêa Filho
In Brief Study Design. Translation, revision, back-translation, and 3-way validity were performed. Objective. The objective of this study was to translate a version of the Oswestry Disability Index (ODI) into Brazilian Portuguese and evaluate its reliability. Summary of Background Data. Reports in t...
Denise Kendrick, Katherine Fielding, Elaine Bentley, Robert Kerslake et al.
OBJECTIVE: To test the hypothesis that radiography of the lumbar spine in patients with low back pain is not associated with improved clinical outcomes or satisfaction with care. DESIGN: Randomised unblinded controlled trial. SETTING: 73 general practices in Nottingham, north Nottinghamshire, southe...
William M. Wara, Theodore L. Phillips, Glenn E. Sheline, James G. Schwade
A series of nine cases of radiation myelopathy seen at the University of California, San Francisco (UCSF) is reviewed, and their treatment data converted into nominal single doses (NSD) and equivalent single doses (ED). The 1% incidence level of myelopathy in the thoracic cord is 1015 rets (ED), and...
Wade Johannessen, Dawn M. Elliott
STUDY DESIGN: The biphasic compressive material properties of normal and degenerate human nucleus pulposus tissue were measured in confined compression. OBJECTIVES: The objective of this study was to determine the effects of degeneration and age on the mechanical properties of human nucleus pulposus...
Jean‐Marc Mac‐Thiong, Ensor E. Transfeldt, Amir A. Mehbod, Joseph H. Perra et al.
STUDY DESIGN: This study prospectively evaluated the health related quality of life (HRQOL) of 73 adults presenting with scoliosis at a single institution, as related to their spinal (C7 plumbline) and global (gravity line) balance. OBJECTIVE: To assess the influence of sagittal and coronal balance ...
Pradeep K. Narotam, Sunil Jose, Narendra Nathoo, Charles Taylon et al.
STUDY DESIGN: Retrospective review of 110 patients undergoing spinal dural repair and regeneration using an onlay, suture-free, 3-dimensional-collagen matrix graft (DuraGen) over an 8-year period (1995-2003). OBJECTIVES: Technique appraisal of collagen matrix to repair spinal dura following incident...
Alexis Falicov, Charles G. Fisher, Joe Sparkes, Michael Boyd et al.
STUDY DESIGN: Prospective clinical study. OBJECTIVE: To assess Health-Related Quality of Life outcomes in patients undergoing surgery for spinal metastases. SUMMARY OF BACKGROUND DATA: Increasing life expectancy of patients with spinal metastases has resulted in greater interest in overall quality o...
Helen E. Gruber, Tracy Johnson, Kelly Leslie, Jane A. Ingram et al.
STUDY DESIGN: Work presented here used a small animal model to illustrate the feasibility of autologous disc cell implantation. OBJECTIVES: To develop a small animal model for autologous disc cell implantation. SUMMARY OF THE BACKGROUND DATA: The use of autologous disc cells in the potential treatme...
John H. Harris, Beth S. Edeiken‐Monroe, Dennis R. Kopaniky
This article presents a practical classification of acute cervical spine injuries based on terminology with generally accepted and understood definitions, published results of experimentally produced acute injuries of the cervical spine, and the correlation of the radiographic and pathologic charact...
Dongliang Wang, Sheng‐Dan Jiang, Li‐Yang Dai
STUDY DESIGN: This study attempts to determine the biologic response of the intervertebral disc to static and dynamic compression in vitro. OBJECTIVE: To quantitate and compare the changes of histology, Type I and II collagens, aggrecan, interleukin (IL)-1beta, and tumor necrosis factor (TNF)-alpha ...
Dawn M. Elliott, Joseph J. Sarver
STUDY DESIGN: Measure the mechanical properties of the mouse and rat disc in compression and torsion. OBJECTIVES: Validate mouse and rat disc as a biomechanical model of the human disc by comparing the normalized properties in compression and torsion loading. SUMMARY OF BACKGROUND DATA: Rodents have...
Alejandro Marquez‐Lara, Sreeharsha V. Nandyala, Sriram Sankaranarayanan, Mohamed Noureldin et al.
STUDY DESIGN: Retrospective analysis. OBJECTIVE: A national population-based database was analyzed to characterize the risks of postoperative complications and mortality associated with the patient's body mass index (BMI) after lumbar spinal surgery. SUMMARY OF BACKGROUND DATA: Obesity has been asso...
Edward R. Savolaine, Jyoti Pandya, Samuel H. Greenblatt, Steven R. Conover
The anatomy of the lumbar epidural space was demonstrated in 40 patients by computed tomography (CT) examinations performed after epidural injection of noninonic radiographic contrast material into the sacral caudal canal via percutaneous catheter. Radiologic evaluation of the epidural space was per...
Chan Shik Shim, Sang‐Ho Lee, Ho-Dong Shin, Han Sug Kang et al.
In Brief Study Design. A retrospective study. Objectives. To evaluate and compare clinical and radiologic outcomes of the CHARITÉ and ProDisc. Summary of Background Data. There is no clinical report comparing CHARITÉ and ProDisc. Methods. Among a total of 61 patients who underwent total disc replace...
Casey L. Korecki, Jeffrey J. MacLean, James C. Iatridis
STUDY DESIGN: A bovine intervertebral disc organ culture model was used to study the effect of dynamic compression magnitude on mechanical behavior and measurement of biosynthesis rate, cell viability, and mRNA expression. OBJECTIVE: The objective of this study was to examine the effect of loading m...
Kevin A. Gillespie, James P. Dickey
STUDY DESIGN: Porcine lumbar spine specimens were cyclically loaded in flexion and extension with a pure moment. The resistance to flexion and extension of the individual spinal elements was quantified using a sequential resection procedure. OBJECTIVE: To determine the biomechanical contribution of ...
Caroline N. Demers, John Antoniou, Fackson Mwale
In Brief Study Design. The contents of DNA, proteoglycan, type II collagen, and denatured type II collagen in the bovine coccygeal intervertebral discs were examined in situ in relation to disc level, age, and tissue region. Objective. To determine whether bovine coccygeal discs are a suitable model...
Jeremy M. Jacobs, Robert Hammerman‐Rozenberg, Aaron Cohen, Jochanan Stessman
In Brief Study Design. A longitudinal age homogeneous cohort study. Objective. To describe the prevalence, nature, and predictors of chronic back pain (CBP) in older people. Summary of Background Data. CBP is a growing source of morbidity among the elderly. Few longitudinal studies exist, and its ti...
Masahiko Takahata, Manabu Ito, Kuniyoshi Abumi, Yoshihisa Kotani et al.
STUDY DESIGN: A retrospective review. OBJECTIVE: This study examined the clinical outcomes of circumferential spinal cord decompression through a posterior approach for thoracic ossification of posterior longitudinal ligament (OPLL), to determine the efficacy of this procedure and the incidence of c...