Mélisande Bernard, Emile Jubeli, Michael D. Pungente, Najet Yagoubi
Biomaterials play an increasing role in modern health care systems. Biocompatibility poses a significant challenge for manufacturers of medical devices and contemporary intelligent drug delivery technologies from materials development to market approval. Despite a highly regulated environment, bioco...
Md Soriful Islam, Andrea Ciavattini, Felice Petraglia, Mario Castellucci et al.
BACKGROUND: Uterine leiomyoma (also known as fibroid or myoma) is the most common benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can produce serious clinical symptoms, including excessive uterine bleeding, pelvic pain or pressure, infertility and pregnancy...
K. J. M. Aung, Armand Van Deun, Erik De Clercq, Mihir Ranjan Sarker et al.
SETTING: Tuberculosis (TB) program, Damien Foundation Projects, Bangladesh. OBJECTIVE: To summarize the outcome and its determinants of the first treatment for multidrug-resistant TB using a standardized regimen consisting of a minimum 9 months. DESIGN: This was a prospective, observational study of...
P.J. Devereaux, Maura Marcucci, Thomas Painter, David Conen et al.
BACKGROUND: Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. METHODS: We conducted a trial involving patients undergoing noncardiac surgery. Patients were randomly assigned to receive trane...
Evin Gultepe, Dattatri Nagesha, Srinivas Sridhar, Mansoor M. Amiji
The characteristics of nanoporous inorganic coatings on implants or on implantable devices are reviewed. The commonly used nanoporous materials, such as aluminum oxide (Al(2)O(3)), titanium oxide (TiO(2)) and porous silicon are highlighted with illustrative examples. The critical issues for sustaine...
Khalequ Zaman
Tuberculosis (TB) is an ancient disease that has affected mankind for more than 4,000 years (1). It is a chronic disease caused by the bacillus Mycobacterium tuberculosis and spreads from person to person through air. TB usually affects the lungs but it can also affect other parts of the body, such ...
Denise Kendrick, Katherine Fielding, Elaine Bentley, Robert Kerslake et al.
OBJECTIVE: To test the hypothesis that radiography of the lumbar spine in patients with low back pain is not associated with improved clinical outcomes or satisfaction with care. DESIGN: Randomised unblinded controlled trial. SETTING: 73 general practices in Nottingham, north Nottinghamshire, southe...
Erik Poulsen, Gláucia Helena Gonçalves, Alessio Bricca, Ewa M. Roos et al.
Objective To estimate knee osteoarthritis (OA) risk following anterior cruciate ligament (ACL), meniscus or combined ACL and meniscus injury. Design Systematic review and meta-analysis. Data sources MEDLINE, Embase, SPORTDiscus, CINAHL and Web of Science until November 2018. Eligibility criteria for...
William M. Wara, Theodore L. Phillips, Glenn E. Sheline, James G. Schwade
A series of nine cases of radiation myelopathy seen at the University of California, San Francisco (UCSF) is reviewed, and their treatment data converted into nominal single doses (NSD) and equivalent single doses (ED). The 1% incidence level of myelopathy in the thoracic cord is 1015 rets (ED), and...
Andrew J. Ball, R. C. L. FENELEY, Paul Abrams
One hundred and seven patients with symptoms of prostatic obstruction in whom prostatectomy was not clinically indicated were reviewed after an interval of 5 years. Ten had subsequently required surgery and 97 remained untreated. In the majority, symptoms did not worsen and only 2 developed acute re...
F. Gerry R. Fowkes, C. J. Evans, Amanda Lee
Venous disease in the legs occurs very commonly in the general population in Western countries. Around one third of women have trunk varices. A lower prevalence has been observed in men but some recent surveys have suggested that the occurrence in men may be comparable to that in women. The prevalen...
Sriram Krishnaswamy, W R Church, Michael E. Nesheim, Kenneth G. Mann
The kinetics of the activation of human prothrombin catalyzed by human prothrombinase was studied using the fluorescent alpha-thrombin inhibitor dansylarginine-N-(3-ethyl-1,5-pentanediyl)amide (DAPA). Prothrombinase proteolytically activates prothrombin to alpha-thrombin by cleavages at Arg273-Thr27...
David P. Strum, Jerrold H. May, Luís G. Vargas
BACKGROUND: Medical institutions are under increased economic pressure to schedule elective surgeries efficiently to contain the costs of surgical services. Surgical scheduling is complicated by variability inherent in the duration of surgical procedures. Modeling that variability, in turn, provides...
HL McLachlan, DA Forster, MA Davey, Thomas J. Farrell et al.
OBJECTIVE: To determine whether primary midwife care (caseload midwifery) decreases the caesarean section rate compared with standard maternity care. DESIGN: Randomised controlled trial. SETTING: Tertiary-care women's hospital in Melbourne, Australia. POPULATION: A total of 2314 low-risk pregnant wo...
M Abdullah-Al-Amin, SMK Nahar Begum, MAK Pramanik
This report presents two cases of Lichen Sclerosus et atrophicus. Patients were prepubertal females having itchy white plaques in the vulvar region with on and off burning micturition. No extragenital involvement was seen. Diagnosis was confirmed by histopathology. They were treated with local appli...