Anne CC Lee, Joanne Katz, Hannah Blencowe, Simon Cousens et al.
BACKGROUND: National estimates for te numbers of babies born small for gestational age and te comorbidity wit preterm birt are unavailable. We aimed to estimate te prevalence of term and preterm babies born small for gestational age (term-SGA and preterm-SGA), and te relation to low birtweig...
Abdullah H Baqui, Shams El Arifeen, Gary L. Darmstadt, Saifuddin Ahmed et al.
BACKGROUND Neonatal mortality accounts for a high proportion of deaths in children under the age of 5 years in Bangladesh. Therefore the project for advancing the health of newborns and mothers (Projahnmo) implemented a community-based intervention package through government and non-government organ...
Shams El Arifeen, Robert E. Black, Gretchen Antelman, Abdullah H Baqui et al.
OBJECTIVES: To describe breastfeeding practices and investigate the influence of exclusive breastfeeding in early infancy on the risk of infant deaths, especially those attributable to respiratory infections (ARI) and diarrhea. METHODS: A prospective observational study was conducted on a birth coho...
Xin Wang, You Li, Katherine L. O’Brien, Shabir A. Madhi et al.
BACKGROUND: Seasonal influenza virus is a common cause of acute lower respiratory infection (ALRI) in young children. In 2008, we estimated that 20 million influenza-virus-associated ALRI and 1 million influenza-virus-associated severe ALRI occurred in children under 5 years globally. Despite this s...
Eleanor Wilson, Jaya Goswami, Abdullah H Baqui, Pablo Alexis Doreski et al.
BACKGROUND: Respiratory syncytial virus (RSV) can cause substantial morbidity and mortality among older adults. An mRNA-based RSV vaccine, mRNA-1345, encoding the stabilized RSV prefusion F glycoprotein, is under clinical investigation. METHODS: In this ongoing, randomized, double-blind, placebo-con...
Shabir A. Madhi, Fernando P. Polack, Pedro A. Piedra, Flor M. Muñoz et al.
BACKGROUND: Respiratory syncytial virus (RSV) is the dominant cause of severe lower respiratory tract infection in infants, with the most severe cases concentrated among younger infants. METHODS: Healthy pregnant women, at 28 weeks 0 days through 36 weeks 0 days of gestation, with an expected delive...
Anne CC Lee, Luke C. Mullany, Alain K. Koffi, Iftekhar Rafiqullah et al.
Abstract Background Urinary tract infection (UTI) in pregnancy, including asymptomatic bacteriuria, is associated with maternal morbidity and adverse pregnancy outcomes, including preterm birth and low birthweight. In low-middle income countries (LMICs), the capacity for screening and treatment of U...
Abdullah H Baqui, Robert E. Black, Shams El Arifeen, Mohammad Yunus et al.
Abstract Objective: To evaluate the effect on morbidity and mortality of providing daily zinc for 14 days to children with diarrhoea. Design: Cluster randomised comparison. Setting: Matlab field site of International Center for Diarrhoeal Disease Research, Bangladesh. Participants: 8070 children age...
Maureen M. Black, Abdullah H Baqui, K. Zaman, Lars Åke Persson et al.
BACKGROUND Iron and zinc deficiency are prevalent during infancy in low-income countries. OBJECTIVES The objectives were to examine whether a weekly supplement of iron, zinc, iron+zinc, or a micronutrient mix (MM) of 16 vitamins and minerals would alter infant development and behavior. DESIGN The pa...
Shams El Arifeen, DM Emdadul Hoque, Tasnima Akter, Muntasirur Rahman et al.
Background WHO and UNICEF launched the Integrated Management of Childhood Illness (IMCI) strategy in the mid-1990s to reduce deaths from diarrhoea, pneumonia, malaria, measles, and malnutrition in children younger than 5 years. We assessed the effect of IMCI on health and nutrition of children young...
Samir K. Saha, Stephanie J. Schrag, Shams El Arifeen, Luke C. Mullany et al.
BACKGROUND: More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated the incidence of community-acquired infections caused by specific organisms among neonates in south Asia. METHODS: From 2011 to 2014, ...
Abdullah H Baqui, Robert E. Black, Mohammad Yunus, Ashfaqul Hoque et al.
Baqui A H (Community Health Division, International Center for Diarrhoeal Disease Research, Bangladesh) (ICDDR, B) GPO Box 128, Dhaka-1000, Bangladesh), Black R E, Yunus Md, Hoque A R A, Chowhury H R and Sack R B. Methodological issues in diarrhoeal diseases epidemiology: definition of diarrhoeal ep...
Aamer Imdad, Luke C. Mullany, Abdullah H Baqui, Shams El Arifeen et al.
BACKGROUND: There is an increased risk of serious neonatal infection arising through exposure of the umbilical cord to invasive pathogen in home and facility births where hygienic practices are difficult to achieve. The World Health Organization currently recommends 'dry cord care' because of insuff...
Peter J. Winch, Ashraful Alam, Afsana Akther, Dilara Afroz et al.
Background Understanding of local knowledge and practices relating to the newborn period, as locally defined, is needed in the development of interventions to reduce neonatal mortality. We describe the organisation of the neonatal period in Sylhet District, Bangladesh, the perceived threats to the w...
Shams El Arifeen, Luke C. Mullany, Rashed Shah, Ishtiaq Mannan et al.
Background Up to half of neonatal deaths in high mortality settings are due to infections, many of which can originate through the freshly cut umbilical cord stump. We aimed to assess the effectiveness of two cord-cleansing regimens with the promotion of dry cord care in the prevention of neonatal m...