Fahmida Chowdhury, Abu Sadat Mohammad Sayeem Bin Shahid, Probir Kumar Ghosh, Mustafizur Rahman et al.
BACKGROUND: In Bangladesh, pneumonia has a higher mortality among malnourished children aged <5 years. Evaluating pneumonia etiology among malnourished children may help improve empiric treatment guidelines. METHODS: During April 2015-December 2017, we conducted a case-control study among severe acu...
Irin Parvin, K. M. Shahunja, Soroar Hossain Khan, Tahmina Alam et al.
The efficacy of commonly used antibiotics for treating severe cholera has been compromised over time because of the reduced antibiotic susceptibility. This study aimed to describe the rate of detection of Vibrio cholerae O1 from fecal samples and antimicrobial susceptibility profiles of V. cholerae ...
Mohammod Jobayer Chisti, Chowdhury Ali Kawser, Abu Sayem Mirza Md. Hasibur Rahman, Abu Sadat Mohammad Sayeem Bin Shahid et al.
Data are limited on the prevalence and outcome of anemia and its risk on mortality among children under five years of age hospitalized for pneumonia/severe pneumonia. Thus, we conducted a secondary analysis of data extracted from Dhaka Hospital of International Centre for Diarrhoeal Disease Research...
Bernard E. Ebruke, Maria Deloria Knoll, Meredith Haddix, Syed M. A. Zaman et al.
BACKGROUND: An improved understanding of childhood pneumonia etiology is required to inform prevention and treatment strategies. Lung aspiration is the gold standard specimen for pneumonia diagnostics. We report findings from analyses of lung and pleural aspirates collected in the Pneumonia Etiology...
Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Ali Fazal Khan, Ali Faisal Saleem et al.
Background: A better understanding of which children are likely to die during acute illness will help clinicians and policy makers target resources at the most vulnerable children. We used machine learning to characterise mortality in the 30-days following admission and the 180-days after discharge ...
W. Abdullah Brooks, Khalequ Zaman, Doli Goswami, Christine Prosperi et al.
Background: Pneumonia remains the leading infectious cause of death among children <5 years, but its cause in most children is unknown. We estimated etiology for each child in 2 Bangladesh sites that represent rural and urban South Asian settings with moderate child mortality. Methods: As part of...
Yasmin Jahan, Michiko Moriyama, Md Moshiur Rahman, Kana Kazawa et al.
Background: Hypertension (HTN) is well established as a leading cause of common serious illnesses worldwide. We carried out this qualitative research to understand perception of and experiences related to HTN among rural Bangladeshi hypertensive women. Methods: A total of 74 female hypertensive part...
Md. Fakhar Uddin, Sassy Molyneux, Kui Muraya, Md. Alamgir Hossain et al.
BACKGROUND: Post-hospital discharge mortality risk is high among young children in many low and middle-income countries (LMICs). The available literature suggests that child, caregiver and health care provider gender all play important roles in post-discharge adherence to medical advice, treatment-s...
Fahmida Chowdhury, Abu Sadat Mohammad Sayeem Bin Shahid, Mosharrat Tabassum, Irin Parvin et al.
INTRODUCTION: Vitamin D is important for its immunomodulatory role and there is an independent association between vitamin D deficiency and pneumonia. We assessed the effect of vitamin D supplementation on the outcome in children hospitalized for severe pneumonia. METHODS: This was a randomised, dou...
K. M. Shahunja, Tahmeed Ahmed, Md Iqbal Hossain, Md Munirul Islam et al.
Background Diarrhea is one of the leading causes of mortality in children under five globally. When it is associated with bacteremia, mortality is even higher. However, bacteraemia in diarrheal children has gained little attention in spite of its deleterious impact in under-five mortality. So, we ai...
James M. Njunge, Kirkby D. Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid et al.
<ns4:p> <ns4:bold>Introduction</ns4:bold> : Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest optimal pathways to ta...
Shamsun Nahar Shaima, Sumon Kumar Das, Shahnawaz Ahmed, Yasmin Jahan et al.
Among all intestinal parasitosis, giardiasis has been reported to be associated with delayed growth in malnourished children under 5 living in low- and middle-income countries. Relevant data on the nutritional status of children aged 0–59 months presenting with moderate-to-severe diarrhea (MSD) and ...
Irin Parvin, Abu Sadat Mohammad Sayeem Bin Shahid, Subhasish Das, Lubaba Shahrin et al.
BACKGROUND: After a multi-country Asian outbreak of cholera due to Vibrio cholerae serogroup O139 which started in 1992, it is rarely detected from any country in Asia and has not been detected from patients in Africa. METHODOLOGY/PRINCIPAL FINDINGS: We extracted surveillance data from the Dhaka and...
K. M. Shahunja, Tahmeed Ahmed, Abu Syeed Golam Faruque, Abu Sadat Mohammad Sayeem Bin Shahid et al.
We aimed to evaluate the factors associated with nosocomial infections (NIs) in under-5 children and in bacterial isolates from their blood, urine, and stool. We reviewed all under-5 hospitalized children with clinically diagnosed NIs in the inpatient ward at Dhaka Hospital of International Centre f...
Céline Bourdon, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Md Alfazal Khan et al.
Background: Growth faltering is well-recognized during acute childhood illness and growth acceleration during convalescence, with or without nutritional therapy, may occur. However, there are limited recent data on growth after hospitalization in low- and middle-income countries. Methods: We evaluat...
Monira Sarmin, Monjory Begum, Farhana Islam, Farzana Afroze et al.
BACKGROUND: To describe factors associated with severe sepsis in diarrheal adults and their outcomes and offender in blood and stool to understand their interplay as clinical features of sepsis and severe diarrhea often overlap. METHODS AND RESULTS: We used this retrospective chart analysis employin...
Yasmin Jahan, Michiko Moriyama, Md Moshiur Rahman, Kana Kazawa et al.
BACKGROUND: Hypertension remains one of the foremost noncommunicable diseases that most often lead to cardiovascular diseases and its different complications. The prevalence of hypertension in Bangladesh has been increasing. However, there are very limited studies that have evaluated the impact of h...
Tahmina Alam, Tahmeed Ahmed, Monira Sarmin, Lubaba Shahrin et al.
Children with diarrhea hospitalized for respiratory distress often have fatal outcome in resource-limited settings, although data are lacking on risk factors for death in such children. We sought to evaluate clinical predictors for death in such children. In this prospective cohort study, we enrolle...
Meseret Gebre, Kassa Haile, Trevor Duke, Md. Tanveer Faruk et al.
BACKGROUND: The safety and efficacy of bubble continuous positive airway pressure (bCPAP) for treatment of childhood severe pneumonia outside tertiary care hospitals is uncertain. We did a cluster-randomised effectiveness trial of locally made bCPAP compared with WHO-recommended low-flow oxygen ther...
W. Abdullah Brooks, Khalequ Zaman, Doli Goswami, Christine Prosperi et al.
Background: Pneumonia remains the leading infectious cause of death among children <5 years, but its cause in most children is unknown. We estimated etiology for each child in 2 Bangladesh sites that represent rural and urban South Asian settings with moderate child mortality. Methods: As part of...