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Results for “"Chifat Wong"”

4 results

A high-throughput test enables specific detection of hepatocellular carcinoma

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David Cheishvili, Chifat Wong, Mohammad Mahbubul Karim, Mohammad Golam Kibria et al.

Journal: Nature CommunicationsYear: 2023Citations: 34

High-throughput tests for early cancer detection can revolutionize public health and reduce cancer morbidity and mortality. Here we show a DNA methylation signature for hepatocellular carcinoma (HCC) detection in liquid biopsies, distinct from normal tissues and blood profiles. We developed a classi...

Health SciencesMedicineHepatologyOpen Access
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Clinical validation of peripheral blood mononuclear cell DNA methylation markers for accurate early detection of hepatocellular carcinoma in Asian patients

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David Cheishvili, Chifat Wong, Mohammad Mahbubul Karim, Mohammad Golam Kibria et al.

Journal: Communications MedicineYear: 2024Citations: 8

Hepatocellular carcinoma (HCC), a leading cause of cancer-related deaths globally, poses significant challenges in early detection. Improved diagnostic accuracy can drastically influence patient outcomes, emphasizing the need for innovative, non-invasive biomarkers. This study utilized a cohort of 4...

Health SciencesMedicineHepatologyOpen Access
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<i>epi</i> Liver a novel tumor specific, high throughput and cost-effective blood test for specific detection of liver cancer (HCC)

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David Cheishvili, Chifat Wong, Mohammad Mahbubul Karim, Mohammad Golam Kibria et al.

Journal: medRxivYear: 2021Citations: 3

Abstract Robust cost effective and high-throughput tests for early detection of cancer in otherwise healthy people could potentially revolutionize public-health and the heavy personal and public burden of the morbidity and mortality from cancer. Several studies have delineated tumor specific DNA met...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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epiLiver a novel tumor specific, high throughput and cost-effective blood test for specific detection of liver cancer (HCC)

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David Cheishvili, Chifat Wong, Mohammad Mahbubul Karim, Mohammad Golam Kibria et al.

Journal: Research SquareYear: 2021Citations: 1

Robust cost effective and high-throughput tests for early detection of cancer in otherwise healthy people could potentially revolutionize public-health and the heavy personal and public burden of the morbidity and mortality from cancer. Several studies have delineated tumor specific DNA methylation ...

Life SciencesBiochemistry, Genetics and Molecular BiologyCancer ResearchOpen Access
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