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Results for “"Daniel J. Klionsky"”

3 results

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>

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Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, Mahmoud Abdellatif et al.

Journal: AutophagyYear: 2021Citations: 2602

autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.

Health SciencesMedicineEpidemiologyOpen Access
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Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

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Tomoyuki Sasaki, Shanshan Lian, Alam Khan, Jesse R. Llop et al.

Journal: AutophagyYear: 2016Citations: 65

transporting, lysosomal, V0 subunit ca) led to suppression of the senescence induced by the Spns1 defect, whereas the sole loss of Atp6v0ca led to senescent embryos similar to the single spns1 mutation. Moreover, we discovered that the combined stable defect seen in the presence of both the spns1 an...

Health SciencesMedicineEpidemiologyOpen Access
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Emerging mechanistic insights of selective autophagy in hepatic diseases

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Md. Abdul Alim Al‐Bari, Yuko Ito, Paul G. Thomes, M. Menon et al.

Journal: Frontiers in PharmacologyYear: 2023Citations: 29

Macroautophagy (hereafter referred to as autophagy), a highly conserved metabolic process, regulates cellular homeostasis by degrading dysfunctional cytosolic constituents and invading pathogens via the lysosomal system. In addition, autophagy selectively recycles specific organelles such as damaged...

Health SciencesMedicineEpidemiologyOpen Access
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