Rajni Dhalaria, Dinesh Kumar, Harsh Kumar, Eugenie Nepovimová et al.
Heavy metal accumulation in plants is a severe environmental problem, rising at an expeditious rate. Heavy metals such as cadmium, arsenic, mercury and lead are known environmental pollutants that exert noxious effects on the morpho-physiological and biological attributes of a plant. Due to their mo...
S. K. Goel, Ravinder Pal Singh, Varinder Singh, Harmanjit Singh et al.
Metformin is a plant-based drug belonging to the class of biguanides and is known to treat type-2 diabetes mellitus (T2DM). The drug, combined with controlling blood glucose levels, improves the body's response to insulin. In addition, trials have identified the cardioprotective potential of metform...
Md. Mominur Rhaman, Md. Rezaul Islam, Shopnil Akash, Mobasharah Mim et al.
In recent decades, research scientists, molecular biologists, and pharmacologists have placed a strong emphasis on cutting-edge nanostructured materials technologies to increase medicine delivery to the central nervous system (CNS). The application of nanoscience for the treatment of neurodegenerati...
Yasir Arfat, Imran Zafar, Sheikh Arslan Sehgal, Muhammad Ayaz et al.
Understanding the role of the mitogen-activated protein kinases (MAPKs) signalling pathway is essential in advancing treatments for neurodegenerative disorders like Alzheimer's. In this study, we investigate in-silico techniques involving computer-based methods to extract the MAPK1 sequence. Our app...
Sonali Khanal, M. Radhakrishna Pillai, Md. Shimul Bhuia, Muhammad Torequl Islam et al.
Deregulation of the mechanistic target of the rapamycin (mTOR) pathway plays an important role in cancer genesis and progression, making it an attractive target for cancer treatment. Disrupting the mTOR pathway contributes to uncontrolled cell growth, increased proliferation, and enhanced cell survi...
Md. Mominur Rhaman, Md. Rezaul Islam, Shopnil Akash, Mobasharah Mim et al.
[This corrects the article DOI: 10.3389/fcell.2022.989471.].