Marisa F. Naujokas, Beth Anderson, Habibul Ahsan, H. Vasken Aposhian et al.
BACKGROUND: Concerns for arsenic exposure are not limited to toxic waste sites and massive poisoning events. Chronic exposure continues to be a major public health problem worldwide, affecting hundreds of millions of persons. OBJECTIVES: We reviewed recent information on worldwide concerns for arsen...
Gail A. Wasserman, Xinhua Liu, Faruque Parvez, Habibul Ahsan et al.
Exposure to manganese via inhalation has long been known to elicit neurotoxicity in adults, but little is known about possible consequences of exposure via drinking water. In this study, we report results of a cross-sectional investigation of intellectual function in 142 10-year-old children in Arai...
Wei Zheng, Dale McLerran, Betsy Rolland, Xianglan Zhang et al.
BACKGROUND: Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin. METHODS: We performed pooled analyses to evaluate the association between BMI and the r...
Maria Argos, Tara Kalra, Paul J. Rathouz, Yu Chen et al.
Background Millions of people worldwide are chronically exposed to arsenic through drinking water, including 35–77 million people in Bangladesh. The association between arsenic exposure and mortality rate has not been prospectively investigated by use of individual-level data. We therefore prospecti...
Gail A. Wasserman, Xinhua Liu, Faruque Parvez, Habibul Ahsan et al.
Exposure to arsenic has long been known to have neurologic consequences in adults, but to date there are no well-controlled studies in children. We report results of a cross-sectional investigation of intellectual function in 201 children 10 years of age whose parents participate in our ongoing pros...
Yu Chen, J. H. Graziano, F. Parvez, Mengling Liu et al.
OBJECTIVE: To evaluate the association between arsenic exposure and mortality from cardiovascular disease and to assess whether cigarette smoking influences the association. DESIGN: Prospective cohort study with arsenic exposure measured in drinking water from wells and urine. SETTING: General popul...
Gail A. Wasserman, Xinhua Liu, Faruque Parvez, Habibul Ahsan et al.
BACKGROUND: We recently reported results of a cross-sectional investigation of intellectual function in 10-year-olds in Bangladesh, who had been exposed to arsenic from drinking water in their home wells. OBJECTIVES: We present results of a similar investigation of 301 randomly selected 6-year-olds ...
Alexander van Geen, Yan Zheng, Roelof Versteeg, M. Stute et al.
Arsenic concentrations measured by graphite furnace atomic absorption range from < 5 to 900 μg/L in groundwater pumped from 6000 wells within a 25 km 2 area of Bangladesh. The proportion of wells that exceed the Bangladesh standard for drinking water of 50 μg/L arsenic increases with depth from 2...
Paolo Boffetta, Dale McLerran, Yu Chen, Manami Inoue et al.
BACKGROUND: The occurrence of diabetes has greatly increased in low- and middle-income countries, particularly in Asia, as has the prevalence of overweight and obesity; in European-derived populations, overweight and obesity are established causes of diabetes. The shape of the association of overwei...
Yu Chen, Faruque Parvez, Mary V. Gamble, Tariqul Islam et al.
The contamination of groundwater by arsenic in Bangladesh is a major public health concern affecting 35-75 million people. Although it is evident that high levels (>300 microg/L) of arsenic exposure from drinking water are related to adverse health outcomes, health effects of arsenic exposure at low...
Habibul Ahsan, Yu Chen, Faruque Parvez, Lydia B. Zablotska et al.
Millions of persons around the world are exposed to low doses of arsenic through drinking water. However, estimates of health effects associated with low-dose arsenic exposure have been extrapolated from high-dose studies. In Bangladesh, many persons have been exposed to a wide range of doses of ars...
Yu Chen, W. K. Copeland, Rajesh Vedanthan, Eric J. Grant et al.
OBJECTIVE: To evaluate the association between body mass index and mortality from overall cardiovascular disease and specific subtypes of cardiovascular disease in east and south Asians. DESIGN: Pooled analyses of 20 prospective cohorts in Asia, including data from 835,082 east Asians and 289,815 so...
Malgosia Madajewicz, Alexander Pfaff, Alexander van Geen, Joseph H. Graziano et al.
Habibul Ahsan, Yu Chen, Faruque Parvez, Maria Argos et al.
Health Effects of Arsenic Longitudinal Study (HEALS), a multidisciplinary and large prospective cohort study in Araihazar, Bangladesh, was established to evaluate the effects of full-dose range arsenic (As) exposure on various health outcomes, including premalignant and malignant skin tumors, total ...
Gail A. Wasserman, Xinhua Liu, Faruque Parvez, Pam Factor‐Litvak et al.
Recently, epidemiologic studies of developmental neurotoxicology have been challenged to increase focus on co-exposure to multiple toxicants. Earlier reports, including our own work in Bangladesh, have demonstrated independent associations between neurobehavioral function and exposure to both arseni...