François Lamontagne, Marie-Hélène Masse, Julie Ménard, Sheila Sprague et al.
BACKGROUND: Studies that have evaluated the use of intravenous vitamin C in adults with sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown mixed results with respect to the risk of death and organ dysfunction. METHODS: In this randomized, placebo-controlled tri...
Ellen Johnson Sirleaf, Helen Clark
Attila N. Lázár, D. Clarke, Helen Adams, Abdur Akanda et al.
Coastal Bangladesh experiences significant poverty and hazards today and is highly vulnerable to climate and environmental change over the coming decades. Coastal stakeholders are demanding information to assist in the decision making processes, including simulation models to explore how different i...
Andrew Reid Bell, David Wrathall, Valerie Mueller, Joyce Chen et al.
To date, projections of human migration induced by sea-level change (SLC) largely suggest large-scale displacement away from vulnerable coastlines. However, results from our model of Bangladesh suggest counterintuitively that people will continue to migrate toward the vulnerable coastline irrespecti...
Helena Aguilar, Ander Urruticoechea, Pasi Halonen, Kazuma Kiyotani et al.
INTRODUCTION: Endocrine therapies targeting cell proliferation and survival mediated by estrogen receptor α (ERα) are among the most effective systemic treatments for ERα-positive breast cancer. However, most tumors initially responsive to these therapies acquire resistance through mechanisms that i...
Most. Waheda Rahman Ansary, Ferdous Rezwan Khan Prince, Effi Haque, Farzana Sultana et al.
Plant growth-promoting bacteria that are also capable of suppressing plant pathogenic fungi play an important role in sustainable agriculture. There is a critical need for conducting research to discover, characterize and evaluate the efficacy of new strains of such bacteria in controlling highly ag...
Cody T. Ross, Paul L. Hooper, Jennifer E. Smith, Adrian V. Jaeggi et al.
To address claims of human exceptionalism, we determine where humans fit within the greater mammalian distribution of reproductive inequality. We show that humans exhibit lower reproductive skew (i.e., inequality in the number of surviving offspring) among males and smaller sex differences in reprod...
Felix Achana, Stavros Petrou, Jason Madan, Kamran Khan et al.
BACKGROUND: The 'Prehospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug Administration In Cardiac Arrest' (PARAMEDIC2) trial showed that adrenaline improves overall survival, but not neurological outcomes. We sought to determine the within-trial and lifetime health and...
Natalie Roschnik, Hawa Diarra, Yahia Dicko, Seybou Diarra et al.
Home fortification with micronutrient powders (MNP) has been shown to reduce anaemia, with high overall acceptability and adherence, but there is limited evidence from West Africa. Around 80% of children younger than 5 years are anaemic in Mali, and new interventions are needed. This paper reports o...
Dia Soilemezi, Ana María Palmar Santos, María Victoria Navarta‐Sánchez, Helen C. Roberts et al.
BACKGROUND: Health and social care systems face difficulties in managing multimorbidity, disease burden and complex needs in long-term conditions such as Parkinson's disease. OBJECTIVE: This study aimed to develop a European understanding of how health and social care professionals can collaborate w...
Erik Pihl, Eva Alfredsson, Magnus Bengtsson, Kathryn Bowen et al.
Non-technical summary We summarize some of the past year's most important findings within climate change-related research. New research has improved our understanding of Earth's sensitivity to carbon dioxide, finds that permafrost thaw could release more carbon emissions than expected and that the u...
Peter M. Wayne, Andrew C. Ahn, Janet Clark, Michael R. Irwin et al.
The emerging paradigm of whole person health shares many core principles with traditional complementary and integrative health frameworks, including Tai Chi and qigong (TCQ). In the Fall of 2023, the Harvard Medical School Osher Center for Integrative Health hosted the inaugural international confer...
Joseph Clark, Kate Binnie, Maddie Bond, Michael G. Crooks et al.
It is likely that the burden of breathlessness in low and middle-income countries (LMICs) is much higher than has been estimated using calculations of disease burden and expected prevalence of the symptom. However, most breathlessness research has been conducted in high-income countries and may not ...
Attila N. Lázár, Andrés Payo, Helen Adams, Ali Ahmed et al.
A flexible meta-model, the Delta Dynamic Integrated Emulator Model (ΔDIEM), is developed to capture the socio-biophysical system of coastal Bangladesh as simply and efficiently as possible. Operating at the local scale, calculations occur efficiently using a variety of methods, including linear stat...
Sudipta Dutta, Amena Khatun, Dipali Rani Gupta, Musrat Zahan Surovy et al.
Serratia marcescens strain BTL07, which has the ability to promote growth and suppress plant diseases, was isolated from the rhizoplane of a chili plant. The draft genome sequence data of the strain will contribute to advancing our understanding of the molecular mechanisms underlying plant growth pr...