Amy H.Y. Tong, Marie Evangelista, Ainslie B. Parsons, Hong Xu et al.
In Saccharomyces cerevisiae, more than 80% of the approximately 6200 predicted genes are nonessential, implying that the genome is buffered from the phenotypic consequences of genetic perturbation. To evaluate function, we developed a method for systematic construction of double mutants, termed synt...
Xiaohu You, Cheng‐Xiang Wang, Jie Huang, Xiqi Gao et al.
Abstract The fifth generation (5G) wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized, such as mass connectivity, ultra-reliability, and guaranteed low latency. However, 5G will not meet all requirements of the future...
Chuanfang Zhang, Yonglu Ma, Xuetao Zhang, Sina Abdolhosseinzadeh et al.
A family of 2D transition metal carbides and nitrides known as MXenes has received increasing attention since the discovery of Ti 3 C 2 in 2011. To date, about 30 different MXenes with well‐defined structures and properties have been synthesized, and many more are theoretically predicted to exist. D...
Weisheng Li, Xiaoshu Gong, Zhihao Yu, Liang Ma et al.
The development of next-generation electronics requires scaling of channel material thickness down to the two-dimensional limit while maintaining ultralow contact resistance 1,2 . Transition-metal dichalcogenides can sustain transistor scaling to the end of roadmap, but despite a myriad of efforts, ...
Wei Hong, Zhongke Yuan, Xudong Chen
Abstract The counterfeiting of goods is growing worldwide, affecting practically any marketable item ranging from consumer goods to human health. Anticounterfeiting is essential for authentication, currency, and security. Anticounterfeiting tags based on structural color materials have enjoyed world...
Ying Bai, Yuan Zhang, Bing Han, Li Yang et al.
Circular RNAs (circRNAs) are highly expressed in the CNS and regulate physiological and pathophysiological processes. However, the potential role of circRNAs in stroke remains largely unknown. Here, we show that the circRNA DLGAP4 (circDLGAP4) functions as an endogenous microRNA-143 (miR-143) sponge...
Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang et al.
N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia. However, the possible involvement of m6A modification of mRNA in hypox...
Rongrong Huang, Lei He, Yanyan Xia, Hongpan Xu et al.
Abstract Emerging evidence indicates that exosomes derived from gastric cancer cells enhance tumor migration and invasion through the modulation of the tumor microenvironment. However, it remains a major problem to detect cancer‐specific exosomes due to technical and biological challenges. Most of t...
Mingshan Wang, Mukesh Thakur, Min‐Sheng Peng, Yu Jiang et al.
Despite the substantial role that chickens have played in human societies across the world, both the geographic and temporal origins of their domestication remain controversial. To address this issue, we analyzed 863 genomes from a worldwide sampling of chickens and representatives of all four speci...
Yuan Zhang, Rongrong Huang, Mengjing Cheng, Lirui Wang et al.
BACKGROUND: Inflammasomes have been found to interact with the gut microbiota, and this effect is associated with depression, but the mechanisms underlying this interaction have not been elucidated in detail. RESULTS: The locomotor activity of NLRP3 KO mice was significantly greater than that of the...
Hai‐Xia Zhang, Qin‐Long Hong, Jing Li, Fei Wang et al.
Abstract Photocatalytic reduction of CO 2 to value‐added fuel has been considered to be a promising strategy to reduce global warming and shortage of energy. Rational design and synthesis of catalysts to maximumly expose the active sites is the key to activate CO 2 molecules and determine the reacti...
Hakan Erdem, Daniel R. Lucey
•Healthcare workers (HCW) are part of the frontline in the struggle against the pandemic.•Many HCWs have been infected with SARS-CoV-2 and have ldied worldwide during the pandemic.•We performed an international survey and requested the total numbers of HCW deaths and infections.•Data were obtained f...
Yixin He, Jing Li, Jiancheng Chen, Xiaojun Miao et al.
Nanoplastics in the environment lead to the human exposure to these particles. However, the consequences of this exposure are not yet fully understood. Here, the cytotoxicity of polystyrene nanoparticles (PS-NPs) with a uniform size (50 nm) but distinct surface functionalization (pristine polystyren...
David M. Geiser, Abdullah M. S. Al‐Hatmi, Takayuki Aoki, Tsutomu Arie et al.
Scientific communication is facilitated by a data-driven, scientifically sound taxonomy that considers the end-user’s needs and established successful practice. In 2013, the Fusarium community voiced near unanimous support for a concept of Fusarium that represented a clade comprising all agricultura...
Fangfang Wu, Bing Han, Shusheng Wu, Li Yang et al.
Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in various CNS diseases. However, the potential role of circRNAs in ischemic stroke-associated neuronal injury remains largely unknown. Here, we investigated the important functions of circRNA TLK1 (circTLK1) in this...