Dawn M. Elliott, Joseph J. Sarver
STUDY DESIGN: Measure the mechanical properties of the mouse and rat disc in compression and torsion. OBJECTIVES: Validate mouse and rat disc as a biomechanical model of the human disc by comparing the normalized properties in compression and torsion loading. SUMMARY OF BACKGROUND DATA: Rodents have...
Joseph J. Sarver, Dawn M. Elliott
STUDY DESIGN: Mechanically test lumbar discs of transgenic mice in compression-tension and torsion. OBJECTIVES: Determine if a reduction in type I collagen results in decreased disc mechanics. SUMMARY OF BACKGROUND DATA: Quantitative relationships between disc structure and function would improve th...