Pius Hildebrand, Pradip Kumar Bardhan, Livio Rossi, Shahana Parvin et al.
Background & aims In developing countries where Helicobacter pylori infection is widespread, posttherapeutic recurrence rates may be high. Many of the limited studies available have methodological problems and show varied recurrence rates. We determined late recrudescence rates, true reinfection, an...
Mian Mashhud Ahmad, Mahbubur Rahman, Azharul Karim Rumi, Shafiqul Islam et al.
Epidemiological reports reveal that H. pylori is distributed among all population in the world. The present cross-sectional study was undertaken to see the H. pylori seroprevalence rates among the asymptomatic adults, as yet reportedly no such data available in Bangladesh. Serum samples were collect...
Shamsun Nahar, Asish K. Mukhopadhyay, Rasel Khan, Mian Mashhud Ahmad et al.
Antimicrobial susceptibility of 120 Helicobacter pylori isolates to metronidazole, tetracycline, clarithromycin, and amoxicillin was determined, and 77.5, 15, 10, and 6.6% of the isolates, respectively, were resistant. Only rdxA inactivation and both rdxA and frxA inactivation were responsible for m...
Rasel Khan, Shamsun Nahar, Jinath Sultana, Mian Mashhud Ahmad et al.
Twelve clarithromycin-resistant (MIC, > or = 1 microg/ml) Helicobacter pylori isolates were analyzed for point mutations in the 23S rRNA gene. Sequence analysis of all of the resistant isolates revealed a T-to-C transition mutation at position 2182. Transformation experiments confirmed that a single...
Alaullah Sheikh, Md Saruar Bhuiyan, Farhana Khanam, Fahima Chowdhury et al.
Many currently available diagnostic tests for typhoid fever lack sensitivity and/or specificity, especially in areas of the world where the disease is endemic. In order to identify a diagnostic test that better correlates with typhoid fever, we evaluated immune responses to Salmonella enterica serov...
Mian Mashhud Ahmad, Dewan Saifuddin Ahmed, AHM Rowshon, Swapan Chandra Dhar et al.
BACKGROUND AND AIM: Bangladesh is a developing country with a very high prevalence of Helicobacter pylori infection, which has been ascribed to overcrowding and poor sanitary conditions. It has generally been accepted that the re-infection rate is higher in countries with a high prevalence of H. pyl...
Taufiqur Rahman Bhuiyan, Firdausi Qadri, Prodip Kumar Bardhan, Mian Mashhud Ahmad et al.
Helicobacter pylori is highly endemic in developing countries, but comparatively little is known about mucosal immune responses to H. pylori in these settings. Therefore, we have compared B- and T-cell responses, with a focus on the gastrointestinal mucosa, in H. pylori-infected adults in a developi...
Rasel Khan, Shamsun Nahar, Asish K. Mukhopadhyay, Douglas E. Berg et al.
The occurrence of 16S rRNA gene mutations associated with resistance to tetracycline in H. pylori isolated in Bangladesh was investigated. Tetracycline susceptibility was determined by the agar dilution method. The 16S rRNA genes of these isolates were sequenced and analyzed. A tetracycline accumula...
Motiur Rahman, Asish K. Mukhopadhyay, Shamsun Nahar, Simanti Datta et al.