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Results for “"Runqiu Jiang"”

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HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation

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Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang et al.

Journal: Signal Transduction and Targeted TherapyYear: 2021Citations: 380

N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia. However, the possible involvement of m6A modification of mRNA in hypox...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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