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Results for “"Sabine Ring"”

6 results

The Secreted β-Amyloid Precursor Protein Ectodomain APPsα Is Sufficient to Rescue the Anatomical, Behavioral, and Electrophysiological Abnormalities of APP-Deficient Mice

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Sabine Ring, Sascha W. Weyer, Susanne B. Kilian, Elaine Waldron et al.

Journal: Journal of NeuroscienceYear: 2007Citations: 378

It is well established that the proteolytic processing of the beta-amyloid precursor protein (APP) generates beta-amyloid (Abeta), which plays a central role in the pathogenesis of Alzheimer's disease (AD). In contrast, the physiological role of APP and of its numerous proteolytic fragments and the ...

Health SciencesMedicinePhysiologyOpen Access
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Crystal structure of dibromomethoxyseselin (DBMS), a photobiologically active pyranocoumarin

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A. K. Bauri, Sabine Foro, A. F. M. Mustafizur Rahman

Journal: Acta Crystallographica Section E Crystallographic CommunicationsYear: 2017Citations: 5

The title compound, C 15 H 14 Br 2 O 4 [systematic name: rac -(9 S ,10 R )-3,9-dibromo-10-methoxy-8,8-dimethyl-9,10-dihydropyrano[2,3- h ]chromen-2(8 H )-one], is a pyranocoumarin derivative formed by the bromination of seselin, which is a naturally occurring angular pyranocoumarin isolated from the...

Health SciencesMedicinePharmacologyOpen Access
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Crystal structure of a photobiologically active brominated angular pyranocoumarin: bromo-hydroxy-seselin

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A. K. Bauri, Sabine Foro, A. F. M. Mustafizur Rahman

Journal: Acta Crystallographica Section E Crystallographic CommunicationsYear: 2017Citations: 5

The title compound, C 14 H 13 BrO 3 [systematic name: rac -(9 S ,10 R )-9-bromo-10-hydroxy-8,8-dimethyl-9,10-dihydro-2 H ,8 H -pyrano[2,3- f ]chromen-2-one], is a substituted pyranocoumarin, obtained by bromination of seselin [8,8-dimethyl-2 H ,8 H -pyrano[2,3- f ]chromen-2-one], which was isolated ...

Health SciencesMedicinePharmacologyOpen Access
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<i>rac</i>-(9<i>R</i>,10<i>R</i>)-3,6,9,10-Tetrabromo-8,8-dimethyl-9,10-dihydro-2<i>H</i>,8<i>H</i>-pyrano[2,3-<i>f</i>]chromen-2-one (tetrabromoseselin): a photobiochemically active pyranocoumarin

Verified

A. K. Bauri, Sabine Foro, A. F. M. Mustafizur Rahman

Journal: IUCrDataYear: 2018Citations: 1

The title molecule, C 14 H 10 Br 4 O 3 , is a tetrabrominated substituted pyranocoumarin synthesized by bromination of seselin (systematic name: 8,8-dimethyl-2 H ,8 H -pyrano[2,3- f ]chromene-2-one) isolated from the Indian herb Trachyspermum stictocapum . The pyran ring has a distorted half-chair c...

Health SciencesMedicinePharmacologyOpen Access
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Crystal structure of tetrahydroseselin, an angular pyranocoumarin

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A. K. Bauri, Sabine Foro, A. F. M. Mustafizur Rahman

Journal: Acta Crystallographica Section E Crystallographic CommunicationsYear: 2017Citations: 1

In the title compound, tetrahydroseselin, C 14 H 16 O 3 , a pyranocoumarin [systematic name: 8,8-dimethyl-3,4,9,10-tetrahydro-2 H ,8 H -pyrano[2,3- f ]chromen-2-one] obtained from the hydrogenation of seselin in the presence of Pd/C in MeOH at room temperature, the dihedral angle between the central...

Health SciencesMedicinePharmacologyOpen Access
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Tuning Sugar‐Based Chiral and Flower‐Like Microparticles (Small 38/2021)

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Yawen Yao, Qiyun Tang, Sabine Rosenfeldt, Marcel Krüsmann et al.

Journal: SmallYear: 2021

Chiral Microparticles Supermolecular structures as solid, chiral and flower-like microparticles are obtained from monosaccharide stearoyl esters with variable molecular configurations of sugar rings. Chiral ‘left-handed’ (counterclockwise) and ‘right-handed’ (clockwise) morphologies are induced by d...

Physical SciencesChemistryOrganic ChemistryOpen Access
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