Mohammad Hossain, Robert J. Commons, Nicola Davies, Kamala Thriemer et al.
BACKGROUND: There is a high risk of Plasmodium vivax parasitaemia following treatment of falciparum malaria. Our study aimed to quantify this risk and the associated determinants using an individual patient data meta-analysis in order to identify populations in which a policy of universal radical cu...
MalariaGEN, Ambroise D. Ahouidi, Mozam Ali, Jacob Almagro‐Garcia et al.
<ns3:p>MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 <ns3:italic>Plasmodium falciparum</ns3:italic> samples from MalariaGEN partner studies in...
MalariaGEN, Ishag Adam, Mohammad Shafiul Alam, Sisay Getachew Alemu et al.
<ns3:p> This report describes the MalariaGEN Pv4 dataset, a new release of curated genome variation data on 1,895 samples of <ns3:italic>Plasmodium vivax</ns3:italic> collected at 88 worldwide locations between 2001 and 2017. It includes 1,370 new samples contributed by MalariaGEN and VivaxGEN partn...
Elizabeth C. Oelsner, Laura R. Loehr, Ashley G. Henderson, Kathleen M. Donohue et al.
RATIONALE: One in 12 adults has chronic obstructive pulmonary disease or asthma. Acute exacerbations of these chronic lower respiratory diseases (CLRDs) are a major cause of morbidity and mortality. Valid approaches to classifying cases and exacerbations in the general population are needed to facil...
Arjun Chandna, Nan Shwe Nwe Htun, Thomas J. Peto, Marco Liverani et al.
<ns3:p>In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for patients with febrile illnesses they can provi...
Arjun Chandna, Rusheng Chew, Nan Shwe Nwe Htun, Thomas J. Peto et al.
<ns3:p>In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for patients with febrile illnesses they can provi...
Julia Lee, Ashley Elizabeth Hardin, Bidhan L. Parmar, Francesca Gino
In this research, we examine the unintended consequences of dishonest behavior for one's interpersonal abilities and subsequent ethical behavior. Specifically, we unpack how dishonest conduct can reduce one's generalized empathic accuracy-the ability to accurately read other people's emotional state...
Daniel K. Palmer, Jonathan L. Allen, Paul A. Williams, Ashley Elizabeth Voss et al.
STUDY DESIGN: Retrospective magnetic resonance imaging (MRI)-based study. OBJECTIVE: Our goal was to develop Wiltse's paraspinal surgical approach by determining the precise anatomic locations of the intermuscular cleavage planes formed by the multifidus and longissimus muscles. The primary objectiv...
Arjun Chandna, Endashaw M. Aderie, Riris Andono Ahmad, Eggi Arguni et al.
INTRODUCTION: In rural and difficult-to-access settings, early and accurate recognition of febrile children at risk of progressing to serious illness could contribute to improved patient outcomes and better resource allocation. This study aims to develop a prognostic clinical prediction tool to assi...
Eric P.M. Grist, Jennifer A. Flegg, Georgina Humphreys, Ignacio Más et al.
BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their spatial distribution. These efforts require substantial resources. Here we propose a generic 'smart surveillance' me...
Debashish Das, Phaik Yeong Cheah, Fateha Akter, Dulal Paul et al.
BACKGROUND: Existing evidence suggests that there is often limited understanding among participants in clinical trials about the informed consent process, resulting in their providing consent without really understanding the purpose of the study, specific procedures, and their rights. The objective ...
Christopher G. Jacob, Thuy-Nhien Nguyen, Mayfong Mayxay, Richard J. Maude et al.
ABSTRACT National Malaria Control Programmes (NMCPs) currently make limited use of parasite genetic data. We have developed GenRe-Mekong, a platform for genetic surveillance of malaria in the Greater Mekong Subregion (GMS) that enables NMCPs to implement large-scale surveillance projects by integrat...
Yin Mo, Ying Ding, Yang Cao, Jill Hopkins et al.
<ns3:p> <ns3:bold>Background</ns3:bold> : <ns3:bold/> Antimicrobial resistance surveillance is essential for empiric antibiotic prescribing, infection prevention and control policies and to drive novel antibiotic discovery. However, most existing surveillance systems are isolate-based without suppor...
Munib Mesinovic, Xin Ci Wong, Giri Shan Rajahram, Barbara Wanjiru Citarella et al.
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and with methodological limitations. It is highly important t...
Katherine O’Flaherty, Jo-Anne Chan, Julia C. Cutts, Sophie Zaloumis et al.
Introduction Understanding the human immune response to Plasmodium falciparum gametocytes and its association with gametocytemia is essential for understanding the transmission of malaria as well as progressing transmission blocking vaccine candidates. Methods In a multi-national clinical efficacy t...