Avinash Kavi, Shivaprasad S. Goudar, Manjunath S. Somannavar, Janet Moore et al.
OBJECTIVE: To determine the relation of COVID-19 symptoms to COVID-19 antibody positivity among unvaccinated pregnant women in low- and middle-income countries (LMIC). DESIGN: COVID-19 infection status measured by antibody positivity at delivery was compared with the symptoms of COVID-19 in the curr...
Jean Kim, Denise C. Babineau, Janet Moore, Akila Subramaniam et al.
<ns3:p> Background The Azithromycin Prevention in Labor Use Study (A-PLUS), a large, multi-national randomized trial, was performed to evaluate the improvement of maternal and newborn outcomes following a single dose of azithromycin (AZ) given during labor. However, the immediate and long-term impac...
Seemab Naqvi, Sarah Saleem, Sk Masum Billah, Janet Moore et al.
With the paucity of data available regarding COVID-19 in pregnancy in low- and middle-income countries (LMICs), near the start of the pandemic, the Global Network for Women's and Children's Health Research, funded by the National Institute of Child Health and Human Development (NICHD), initiated fou...
Robert L. Goldenberg, Seemab Naqvi, Sarah Saleem, Marion Koso‐Thomas et al.
COVID-19 infection, a severe acute respiratory syndrome, was declared a global pandemic by the World Health Organization (WHO) in March 2020. During the pandemic, millions of people died and countless others suffered from severe illness [1]. COVID-19 vaccination has shown > 90% effectiveness in prev...
Haleema Yasmin, Saba Tanveer, Shiyam Sunder Tikmani, Janet Moore et al.
OBJECTIVES: Antibiotic use is increasing in low- and middle-income countries (LMIC); however, few studies have examined the rates of use in a population. The use of antibiotics for liveborn infants in LMIC was examined. DESIGN: The study, a planned prospective, observational secondary analysis of th...
Robert L. Goldenberg, Shivaprasad S. Goudar, Avinash Kavi, Nancy F. Krebs et al.
The articles in this supplement reflect presentations made during the third International Conference on Maternal, Newborn and Child Health: Translating Research Evidence to Practice. The conference took place at the Jawaharlal Nehru Medical College (JNMC) in Belagavi, India, between 11 and 13 Novemb...
Saleem Jessani, Sarah Saleem, Elizabeth Fogleman, Sk Masum Billah et al.
OBJECTIVE: To understand trends in the knowledge, attitudes and practices (KAP) of pregnant women related to COVID-19 in seven low- and middle-income countries. DESIGN: Multi-country population-based prospective observational study. SETTING: Study sites in Bangladesh, the Demographic Republic of Con...
Patricia L. Hibberd, Jean Kim, Marissa Trotta, Sixto M. Leal et al.
BACKGROUND: Prophylactic oral azithromycin vs. placebo reduced maternal, but not neonatal, mortality/sepsis in the A-PLUS Randomized Trial. While prophylactic intrapartum azithromycin reduces maternal mortality/sepsis, it may promote antimicrobial resistance (AMR) in commensal bacteria,. METHODS: Ra...
Larissa Kamgue Sidze, Janet L. Moore, Waldemar A. Carlo, Musaku Mwenechanya et al.
OBJECTIVE: A single oral dose of azithromycin (AZM) given during labor to women planning a vaginal delivery reduced maternal infections including sepsis, with a stronger effect in sub-Saharan Africa than South Asia. Since maternal infection contributes to labor dysfunction and postpartum hemorrhage ...
Elizabeth M. McClure, Alan T N Tita, Waldemar A. Carlo, Sarah Saleem et al.
OBJECTIVE: The randomized trial of azithromycin to reduce maternal and neonatal sepsis (the A-PLUS Trial) found substantial reduction in maternal sepsis among women receiving azithromycin and substantial non-study antibiotic use. This secondary analysis explored the effect modification of non-study ...
Rupsa C. Boelig, Avinash Kavi, Janet Moore, Denise C. Babineau et al.
OBJECTIVE: A multi-centre international trial (A-PLUS), demonstrated that a single dose of 2 g oral azithromycin in labour reduced the risk of maternal sepsis or death, but not neonatal mortality. We aimed to determine whether the efficacy of azithromycin in prevention of any maternal infection or n...
Abdullah H Baqui, Mohammod Shahidullah, S Ahmed, Arunangshu Dutta Roy et al.
BACKGROUND: Research has shown low mortality in young infants with a single low-mortality-risk possible serious bacterial infection (PSBI) sign. Outpatient treatment of young infants (age <2 months) with a single low-mortality-risk PSBI sign might be as effective and safe as hospitalisation. Outpati...
William A. Petri, Patricia L. Hibberd, Elizabeth M. McClure, Sana Yousaf et al.
Objective: We sought to understand knowledge, attitudes and practices (KAP) regarding COVID-19 in pregnant women in seven low and middle-income countries (LMIC). Design: Population-based prospective, observational study. Settings: Study sites in DRC, Kenya, Zambia, Bangladesh, India (two sites), Pak...
Sk Masum Billah, Biplob Hossain, Jean Kim, Najia Karim Ghanchi et al.
OBJECTIVES: To determine COVID-19 antibody positivity rates over time and relationships to pregnancy outcomes in low- and middle-income countries (LMICs). DESIGN: With COVID-19 antibody positivity at delivery as the exposure, we performed a prospective, observational cohort study in seven LMICs duri...
Abdullah H Baqui, Mohammod Shahidullah, Salahuddin Ahmed, Arunangshu Dutta Roy et al.
BACKGROUND: In low-resource settings, challenges in hospitalisation stay for sick young infants younger than 2 months persist. Early discharge of young infants with moderate-mortality-risk possible serious bacterial infection (PSBI) signs might provide a safe and effective alternative. We compared t...
Jean Kim, Denise C. Babineau, Janet Moore, Akila Subramaniam et al.
<ns5:p>Background The Azithromycin Prevention in Labor Use Study (A-PLUS), a large, multi-national randomized trial, was performed to evaluate the improvement of maternal and newborn outcomes following a single dose of azithromycin (AZ) given during labor. However, the immediate and long-term impact...
Billah S.M., S. Bucher, Manolo Mazariegos, Hibberd P.L. et al.
Objective: To understand trends in the knowledge, attitudes and practices (KAP) of pregnant women related to COVID-19 in seven low- and middle-income countries. Design: Multi-country population-based prospective observational study. Setting: Study sites in Bangladesh, the Demographic Republic of Con...
Musaku Mwenechanya, Elizabeth M. McClure, Sherri Bucher, Waldemar A. Carlo et al.
With the paucity of data available regarding COVID-19 in pregnancy in low- and middle-income countries (LMICs), near the start of the pandemic, the Global Network for Women's and Children's Health Research, funded by the National Institute of Child Health and Human Development (NICHD), initiated fou...
AL Garces, V. Thorsten, Seemab Naqvi, R.L. Goldenberg et al.
Objectives: We sought to determine the knowledge, attitudes and practices of pregnant women regarding COVID-19 vaccination in pregnancy in seven low- and middle-income countries (LMIC). Design: Prospective, observational, population-based study. Settings: Study areas in seven LMICs: Bangladesh, Indi...