Golam Sarwar Raju, Md Mizanur RahmanMoghal, Mohammad Salim Hossain, Md Mahadi Hassan et al.
BACKGROUND: The current study aims at evaluating the analgesic, anti-pyretic and anti-inflammatory properties of methanolic extract of the stem, bark and leaves of Launaea sarmentosa and Aegialitis rotundifolia roxb. RESULTS: The AELS and AEAR extract presented a significant (***p < 0.001) dose depe...
Maria Argos, Mahfuzar Rahman, Faruque Parvez, James J. Dignam et al.
BACKGROUND: Epidemiologic research suggests that increased cancer risk due to chronic arsenic exposure persists for several decades even after the exposure has terminated. Observational studies suggest that antioxidants exert a protective effect on arsenical skin lesions and cancers among those chro...
Yu Chen, Tyler R. McClintock, Stephanie Segers, Faruque Parvez et al.
Background Dietary pattern analysis is emerging as a practical, effective tool for relating comprehensive dietary intake to risk of cardiovascular disease mortality. However, no studies have applied this technique to a population outside of the developed world. Methods We conducted prospective cohor...
Wenzhen Ge, Faruque Parvez, Fen Wu, Tariqul Islam et al.
Background Anthropometric measures such as waist-hip-ratio (WHR), waist-height-ratio (WHtR), waist circumference, Mid-upper arm circumference (MUAC), and upper thigh circumference, have been linked to the risk of cardiovascular disease (CVD). However, their relationships with subclinical atheroscler...
Golam Sarwar Raju, Mizanur Rahman Moghal, Syed Masudur Rahman Dewan, Mohammad Nurul Amin et al.
OBJECTIVE: The present study was conducted to detect possible chemicals (phytoconstituents), prove ethno-medicinal value of the plant, and investigate antimicrobial, anthelmintic, and total phenolic content of crude methanolic extract of the Solanum violaceum plant. MATERIALS AND METHODS: Phytochemi...
Syed Masudur Rahman Dewan, Mohammad Nurul Amin, Tarek Adnan, Siraj Uddin et al.
Mosiur Rahman, Syed Emdadul Haque, Sarwar Zahan, Md. Jahirul Islam et al.
Objectives We aimed to examine whether an association exists between maternal high-risk fertility behavior and chronic undernutrition among children under 5 y of age. In addition, we explored the relationship between poverty and high-risk fertility behavior and the relative roles they play as obstac...
David Cheishvili, Chifat Wong, Mohammad Mahbubul Karim, Mohammad Golam Kibria et al.
High-throughput tests for early cancer detection can revolutionize public health and reduce cancer morbidity and mortality. Here we show a DNA methylation signature for hepatocellular carcinoma (HCC) detection in liquid biopsies, distinct from normal tissues and blood profiles. We developed a classi...
Golam Sarwar, Christian Hogrefe, Barron H. Henderson, Kristen M. Foley et al.
We analyze hourly PM2.5 (particles with an aerodynamic diameter of ≤ 2.5 μm) concentrations measured at the U.S. Embassy in Dhaka over the 2016 - 2021 time period and find that concentrations are seasonally dependent with the highest occurring in winter and the lowest in monsoon seasons. Mean winter...
Md. Sabibul Haque, Mst. Tanziatul Husna, Md. Nesar Uddin, Md. Alamgir Hossain et al.
Global warming is predicted to be increased in the upcoming years, resulting in frequent heatwaves or hot days worldwide, which can seriously affect crop growth and productivity. The responses of heat stress to several photophysiological and biochemical traits in three tomato cultivars were investig...
Dayana A. Delgado, Chenan Zhang, Kevin J. Gleason, Kathryn Demanelis et al.
Leukocyte telomere length (LTL) is a heritable trait with two potential sources of heritability (h2): inherited variation in non-telomeric regions (e.g., SNPs that influence telomere maintenance) and variability in the lengths of telomeres in gametes that produce offspring zygotes (i.e., “direct” in...
Yu-Hsuan Shih, Caitlin G. Howe, Molly Scannell Bryan, Hasan Shahriar et al.
Background: Hypertension in later life, a significant risk factor for cardiovascular disease, has been linked to elevated blood pressure in early life. Exposure to metals may influence childhood blood pressure; however, previous research is limited and has mainly focused on evaluating the toxicity o...
Fen Wu, Liang Chi, Hongyu Ru, Faruque Parvez et al.
BACKGROUND: Chronic exposure to inorganic arsenic from drinking water has been associated with a host of cancer and noncancer diseases. The application of metabolomics in epidemiologic studies may allow researchers to identify biomarkers associated with arsenic exposure and its health effects. OBJEC...
Fen Wu, Faruque Parvez, Tariqul Islam, Alauddin Ahmed et al.
OBJECTIVE: To evaluate the potential effects of betel quid chewing on mortality. (A quid consists of betel nut, wrapped in betel leaves; tobacco is added to the quid by some users). METHODS: Prospective data were available on 20 033 individuals aged 18-75 years, living in Araihazar, Bangladesh. Demo...
Yu Chen, Wenzhen Ge, Faruque Parvez, Sripal Bangalore et al.
BACKGROUND: Epidemiological studies have observed protective effects of mid-upper arm circumference (MUAC) against all-cause mortality mostly in Western populations. However, evidence on cause-specific mortality is limited. METHODS: The sample included 19 575 adults from a population-based cohort st...
Brandon L. Pierce, Tong Lin, Samantha G. Dean, Maria Argos et al.
Inorganic arsenic (iAs) is a carcinogen, and exposure to iAs via food and water is a global public health problem. iAs-contaminated drinking water alone affects >100 million people worldwide, including ~50 million in Bangladesh. Once absorbed into the blood stream, most iAs is converted to mono-meth...
Faruque Parvez, Fredine T. Lauer, Pam Factor‐Litvak, Xinhua Liu et al.
Arsenic and polycyclic aromatic hydrocarbons (PAH) are environmental pollutants to which people around the world are exposed through water, food and air. In mouse and in vitro studies of human cells, both of these chemicals have been shown to modulate the immune system. In some experimental studies,...
Fen Wu, Farzana Jasmine, Muhammad G. Kibriya, Mengling Liu et al.
Epidemiologic studies that evaluated genetic susceptibility to the effects of arsenic exposure from drinking water on subclinical atherosclerosis are limited. We conducted a cross-sectional study of 1,078 participants randomly selected from the Health Effects of Arsenic Longitudinal Study in Banglad...
Md Tarikul Islam, Suprovath Kumar Sarkar, Nusrat Sultana, Mst. Noorjahan Begum et al.
BACKGROUND: Bangladesh lies in the global thalassemia belt, which has a defined mutational hot-spot in the beta-globin gene. The high carrier frequencies of beta-thalassemia trait and hemoglobin E-trait in Bangladesh necessitate a reliable DNA-based carrier screening approach that could supplement t...
Md. Golam Mahabub Sarwar, Aminul Islam