Jan Bonhoeffer, Egeruan B. Imoukhuede, Grace M. Aldrovandi, Novilia Sjafri Bachtiar et al.
This document is intended as a guide to the protocol development for trials of prophylactic vaccines. The template may serve phases I-IV clinical trials protocol development to include safety relevant information as required by the regulatory authorities and as deemed useful by the investigators. Th...
R. N. Oram, M.A.Q. Shaikh, Khalequz Zaman, A. H. D. Brown
Warda Haque, Jahurul Haque, Dipan Barai, Sezanur Rahman et al.
Group A rotavirus causes a substantial proportion of diarrhoea related deaths worldwide among children under five years. We analyzed rotavirus prevalence and genotypes distribution among patients admitted with diarrhoea at icddr,b hospital in Dhaka during 2012-16. Stool specimens (n = 1110) were col...
Haruko Takeuchi, Md Alfazal Khan, Mohammad Yunus, Mohammad Imrul Hasan et al.
BACKGROUND: Studies have addressed the immunomodulatory effects of helminths and their protective effects upon asthma. However, anti-Ascaris IgE has been reported to be associated with an increased risk of asthma symptoms. We examined the association between serum levels of anti-Ascaris IgE and bron...
Sayera Banu, Mohammad Khaja Mafij Uddin, Mohammad R. Islam, Khalequz Zaman et al.
OBJECTIVE: To characterise and classify clinical isolates collected from tuberculosis (TB) patients in rural Bangladesh and to investigate the mode of transmission. DESIGN: An epidemiological study using a combination of conventional and molecular methods was performed in a rural population of Bangl...
Mary E. Alao, Jamie Perin, W. Abdullah Brooks, Lokman Hossain et al.
BACKGROUND Deficits in child growth are associated with poor cognitive outcomes and an increased risk for infection and mortality globally. One hundred forty million people are chronically exposed to arsenic from contaminated drinking water worldwide. While arsenic exposure has been associated with ...
Takuya Nakazawa, Md Alfazal Khan, Hiroshi Yasueda, Akemi Saito et al.
There are controversial reports on the relationship between helminthic infection and allergic diseases. Although IgE cross-reactivity between nematode Ascaris antigens and house dust-mite allergens in allergic patients have been reported, whether Ascaris or the mite is the primary sensitizer remains...
Khalequz Zaman, H Miszta, Z Dabrowski
This study was carried out on male Wistar rats. The bone marrow activities of acetylcholinesterase (AchE-EC.3.1.1.7.), glutathione reductase (GR-EC.1.6.4.2.) and glucose-6-phosphate dehydrogenase (G6PD-EC.1.1.1.49.) were determined as affected by aluminium. The present experiments have revealed that...
Josyf C. Mychaleckyj, Rashidul Haque, Marya P. Carmolli, Dadong Zhang et al.
BACKGROUND: The Polio Endgame strategy includes phased withdrawal of oral poliovirus vaccines (OPV) coordinated with introduction of inactivated poliovirus vaccine (IPV) to ensure population immunity. The impact of IPV introduction into a primary OPV series of immunizations in a developing country i...
Haruko Takeuchi, Md Alfazal Khan, Khalequz Zaman, Sayaka Takanashi et al.
Ascaris lumbricoides is the most common soil-transmitted helminth and infects 447 million people in impoverished areas worldwide. It causes serious morbidity including wheezing and influences various aspects of human immunity, such as type 2 innate lymphoid cells, regulatory T cell function, and acq...
Zeaur Rahim, Mst. Sabiha Banu Momi, Sajal Saha, Khalequz Zaman et al.
Khalequz Zaman, Mohammad Yunus, Asma Binte Aziz, Jodi Feser et al.
INTRODUCTION: Japanese encephalitis (JE) virus is one of the leading causes of viral encephalitis across temperate and tropical zones of Asia. The live attenuated SA 14-14-2 JE vaccine (CD-JEV) is one of three vaccines prequalified by the World Health Organization (WHO) to prevent JE. WHO currently ...
Warda Haque, Muhammad Talha, Sezanur Rahman, Mehedi Hasan et al.
Rotavirus gastroenteritis is accountable for an estimated 128 500 deaths among children younger than 5 years worldwide, and the majority occur in low-income countries. Although the clinical trials of rotavirus vaccines in Bangladesh revealed a significant reduction of severe rotavirus disease by aro...
Sunheang Shin, Đặng Đức Anh, Khalequz Zaman, Mohammad Yunus et al.
Shahrin Emdad Rayna, Md. Khalequzzaman, Fahmida Afroz Khan, K M Thouhidur Rahman et al.
Background Bangabandhu Sheikh Mujib Medical University (BSMMU) is a postgraduate medical university in Bangladesh, where health research is an institutional mission. To improve the institutional research culture that contributes to better research capabilities, an assessment of BSMMU’s research outp...