Brandon L. Pierce, Tong Lin, Maria Argos, Kathryn Demanelis et al.
Inherited genetic variation affects local gene expression and DNA methylation in humans. Most expression quantitative trait loci (cis-eQTLs) occur at the same genomic location as a methylation QTL (cis-meQTL), suggesting a common causal variant and shared mechanism. Using DNA and RNA from peripheral...
Mahfuzar Rahman, Marie Vahter, Nazmul Sohel, Mohammad Yunus et al.
BACKGROUND: The objective of this population-based case-referent study in Matlab, Bangladesh, was to assess the susceptibility to arsenic-induced skin lesions by age and sex, in a population drinking water from As-contaminated tube wells. METHODS: Identification of As-related skin lesions was carrie...
Marika Berglund, Anna‐Lena Lindberg, Mahfuzar Rahman, Mohammad Yunus et al.
Background Little is known about the variation in exposure to toxic metals by age and gender and other potential modifying factors. We evaluated age and gender differences by measurements of metal/element concentrations in urine in a rural population in Matlab, Bangladesh, in three age groups: 8-12 ...
Fakir Md Yunus, Safayet Khan, Priyanka Chowdhury, Abul Hasnat Milton et al.
Arsenic contamination in drinking water has a detrimental impact on human health which profoundly impairs the quality of life. Despite recognition of the adverse health implications of arsenic toxicity, there have been few studies to date to suggest measures that could be taken to overcome arsenic c...
Md. Jakariya, Marie Vahter, Mahfuzar Rahman, MA Wahed et al.
There is an urgent need for Bangladesh to identify the arsenic (As) contaminated tubewells (TWs) in order to assess the health risks and initiate appropriate mitigation measures. This will involve testing water in millions of TWs and raising community awareness about the health problems related to c...
Fahmida Tofail, Marie Vahter, Jena Hamadani, Barbro Nermell et al.
BACKGROUND: Exposure to arsenic-contaminated drinking water during pregnancy is associated with low birth weight and fetal loss, and there is concern that the infants' development may be affected. OBJECTIVE: We assessed the effects of in utero arsenic exposure during pregnancy on infants' problem-so...
Abul Hasnat Milton, Ziul Hasan, Mohammed Atiqur Rahman, Mahfuzar Rahman
Chronic Arsenic Poisoning and Respiratory Effects in Bangladesh: Abul Hasnat Milton, et al. Arsenic Cell, NGO Forum for Drinking Water Supply & Sanitation, Bangladesh —A large population in Bangladesh have been exposed to naturally occurring inorganic arsenic through their drinking water. A prev...
Shafiqul Islam Khan, AK Mottashir Ahmed, Mohammad Yunus, Mahfuzar Rahman et al.
Arsenic contamination of tubewell water is a major public-health problem in Bangladesh. In the recent years, the use of shallow and deep tubewell water for irrigation and the use of excess amount of cheap fertilizers and pesticides containing cadmium pose a serious threat of contamination of arsenic...
Maria Argos, Lin Chen, Farzana Jasmine, Tong Lin et al.
BACKGROUND: Inorganic arsenic is one of the most common naturally occurring contaminants found in the environment. Arsenic is associated with a number of health outcomes, with epigenetic modification suggested as a potential mechanism of toxicity. OBJECTIVE: Among a sample of 400 adult participants,...
Anna‐Lena Lindberg, Nazmul Sohel, Mahfuzar Rahman, Lars Åke Persson et al.
BACKGROUND: We recently reported that the main reason for the documented higher prevalence of arsenic-related skin lesions among men than among women is the result of less efficient arsenic metabolism. OBJECTIVE: Because smoking has been associated with less efficient arsenic methylation, we aimed t...
Mahfuzar Rahman, Nazmul Sohel, Mohammad Yunus, Mahbub Elahi Chowdhury et al.
BACKGROUND: Arsenic in drinking water was associated with increased risk of all-cause, cancer, and cardiovascular death in adults. However, the extent to which exposure is related to all-cause and deaths from cancer and cardiovascular condition in young age is unknown. Therefore, we prospectively as...
Sheikh Mohammed Shariful Islam, Riaz Uddin, Subasish Das, Syed Imran Ahmed et al.
BACKGROUND: Bangladesh has made substantial progress in improving socioeconomic and health indicators over the past 50 years, but data on national disease burden are scarce. We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to estimate the burden of disease...
Islay Mactaggart, Wolf‐Peter Schmidt, Kristof Bostoen, Joseph J. Chunga et al.
OBJECTIVES: To assess access to adequate water, sanitation and hygiene (WASH) among people with disabilities at the household and individual level. DESIGN: Cross-sectional surveys. SETTING: Data were included from five district-level or regional-level surveys: two in Bangladesh (Bangladesh-1, Bangla...
Kathryn Demanelis, Maria Argos, Tong Lin, Justin Shinkle et al.
BACKGROUND: Arsenic exposure affects [Formula: see text] people worldwide, including [Formula: see text] in Bangladesh. Arsenic exposure increases the risk of cancer and other chronic diseases, and one potential mechanism of arsenic toxicity is epigenetic dysregulation. OBJECTIVE: We assessed associ...
Mohammad Yunus, Nazmul Sohel, Samar Kumar Hore, Mahfuzar Rahman
The recent discovery of large-scale arsenic (As) contamination of groundwater has raised much concern in Bangladesh. Reliable estimates of the magnitude of As exposure and related health problems have not been comprehensively investigated in Bangladesh. A large population-based study on As and healt...