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Results for “"Md. Ashraf Uddin"”

31+ results

Toxic tau: structural origins of tau aggregation in Alzheimer's disease

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MdSahab Uddin, GhulamMd Ashraf, AbdullahAl Mamun, Bijo Mathew

Journal: Neural Regeneration ResearchYear: 2020Citations: 156

Alzheimer's disease is characterized by the extracellular accumulation of the amyloid β in the form of amyloid plaques and the intracellular deposition of the microtubule-associated protein tau in the form of neurofibrillary tangles. Most of the Alzheimer's drugs targeting amyloid β have been failed...

Health SciencesMedicinePhysiologyOpen Access
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DeepCrop: Deep learning-based crop disease prediction with web application

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Md. Manowarul Islam, Md. Adil, Md. Alamin Talukder, Md. Khabir Uddin Ahamed et al.

Journal: Journal of Agriculture and Food ResearchYear: 2023Citations: 152

Agriculture plays a significant role in every nation's economy by producing crops. Plant disease identification is one of the most important aspects of maintaining an agriculturally developed nation. The timely and efficient detection of plant diseases is essential for a healthy and productive agric...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Estrogen Signaling in Alzheimer’s Disease: Molecular Insights and Therapeutic Targets for Alzheimer’s Dementia

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Md. Sahab Uddin, M. M. Rahman, Md. Jakaria, Md. Sohanur Rahman et al.

Journal: Molecular NeurobiologyYear: 2020Citations: 152

Estrogens play a crucial physiological function in the brain; however, debates exist concerning the role of estrogens in Alzheimer's disease (AD). Women during pre-, peri-, or menopause periods are more susceptible for developing AD, suggesting the connection of sex factors and a decreased estrogen ...

Life SciencesBiochemistry, Genetics and Molecular BiologyGenetics
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Knowledge, beliefs, attitudes and perceived risk about COVID-19 vaccine and determinants of COVID-19 vaccine acceptance in Bangladesh

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Sultan Mahmud, Md Mohsin, Ijaz Ahmed Khan, Ashraf Uddin Mian et al.

Journal: PLoS ONEYear: 2021Citations: 147

Bangladesh govt. launched a nationwide vaccination drive against SARS-CoV-2 infection from early February 2021. The objectives of this study were to evaluate the acceptance of the COVID-19 vaccines and examine the factors associated with the acceptance in Bangladesh. In between January 30 to Februar...

Social SciencesHealthVaccine Coverage and HesitancyOpen Access
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Autophagic dysfunction in Alzheimer’s disease: Cellular and molecular mechanistic approaches to halt Alzheimer’s pathogenesis

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Md. Sahab Uddin, Abdullah Al Mamun, Zubair Khalid Labu, Oscar Hidalgo‐Lanussa et al.

Journal: Journal of Cellular PhysiologyYear: 2018Citations: 141

Autophagy is a preserved cytoplasmic self-degradation process and endorses recycling of intracellular constituents into bioenergetics for the controlling of cellular homeostasis. Functional autophagy process is essential in eliminating cytoplasmic waste components and helps in the recycling of some ...

Health SciencesMedicineEpidemiology
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Feasibility and effectiveness of oral cholera vaccine in an urban endemic setting in Bangladesh: a cluster randomised open-label trial

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Firdausi Qadri, Mohammad Ali, Fahima Chowdhury, Ashraful Islam Khan et al.

Journal: The LancetYear: 2015Citations: 137

Background Cholera is endemic in Bangladesh with epidemics occurring each year. The decision to use a cheap oral killed whole-cell cholera vaccine to control the disease depends on the feasibility and effectiveness of vaccination when delivered in a public health setting. We therefore assessed the f...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinology
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Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology

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Md. Farhad Hossain, Md. Sahab Uddin, G. M. Sala Uddin, Dewan Md. Sumsuzzman et al.

Journal: Molecular NeurobiologyYear: 2019Citations: 133

Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning pleiotropic agent which has a wide range of neuroprotective role in manifold age-related neurodegenerative disorders especially Alzheimer's diseases (AD). AD is a devastating neurodegenerative disorder and common form ...

Life SciencesNeuroscienceEndocrine and Autonomic Systems
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Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer’s Disease

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Md. Sahab Uddin, Md. Tanvir Kabir, Kamal Niaz, Philippe Jeandet et al.

Journal: MoleculesYear: 2020Citations: 131

Alzheimer's disease (AD) is one of the utmost chronic neurodegenerative disorders, which is characterized from a neuropathological point of view by the aggregates of amyloid beta (Aβ) peptides that are deposited as senile plaques and tau proteins which form neurofibrillary tangles (NFTs). Even thoug...

Health SciencesMedicinePhysiologyOpen Access
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Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration

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Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Jamil Ahmad et al.

Journal: European Journal of PharmacologyYear: 2020Citations: 130

Neurodegenerative diseases (NDs) are characterized by disorders with progressive deterioration of the structure and/or function of neurons. Genetic mutations can lead to many NDs. Nevertheless, neurodegeneration can also take place due to several biological processes. The pathogenesis of several NDs...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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A deep learning approach using effective preprocessing techniques to detect COVID-19 from chest CT-scan and X-ray images

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Md. Khabir Uddin Ahamed, Manowarul Islam, Ashraf Uddin, Arnisha Akhter et al.

Journal: Computers in Biology and MedicineYear: 2021Citations: 127

Coronavirus disease-19 (COVID-19) is a severe respiratory viral disease first reported in late 2019 that has spread worldwide. Although some wealthy countries have made significant progress in detecting and containing this disease, most underdeveloped countries are still struggling to identify COVID...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Revisiting the Amyloid Cascade Hypothesis: From Anti-Aβ Therapeutics to Auspicious New Ways for Alzheimer’s Disease

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Md. Sahab Uddin, Md. Tanvir Kabir, Md. Sohanur Rahman, Tapan Behl et al.

Journal: International Journal of Molecular SciencesYear: 2020Citations: 122

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder related to age, characterized by the cerebral deposition of fibrils, which are made from the amyloid-β (Aβ), a peptide of 40-42 amino acids. The conversion of Aβ into neurotoxic oligomeric, fibrillar, and protofibrillar assemb...

Health SciencesMedicinePhysiologyOpen Access
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Beneficial Role of Bitter Melon Supplementation in Obesity and Related Complications in Metabolic Syndrome

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Md Ashraful Alam, Riaz Uddin, Nusrat Subhan, Mahbubur Rahman et al.

Journal: Journal of LipidsYear: 2015Citations: 122

Diabetes, obesity, and metabolic syndrome are becoming epidemic both in developed and developing countries in recent years. Complementary and alternative medicines have been used since ancient era for the treatment of diabetes and cardiovascular diseases. Bitter melon is widely used as vegetables in...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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Cyberbullying Detection on Social Networks Using Machine Learning Approaches

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Md. Manowarul Islam, Md. Ashraf Uddin, Linta Islam, Arnisha Akter et al.

Journal: 2020 IEEE Asia-Pacific Conference on Computer Science and Data Engineering (CSDE)Year: 2020Citations: 116

The use of social media has grown exponentially over time with the growth of the Internet and has become the most influential networking platform in the 21st century. However, the enhancement of social connectivity often creates negative impacts on society that contribute to a couple of bad phenomen...

Physical SciencesComputer ScienceArtificial IntelligenceOpen Access
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Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning

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Md. Tanvir Kabir, Md. Sahab Uddin, Mst. Marium Begum, S. Thangapandiyan et al.

Journal: Current Pharmaceutical DesignYear: 2019Citations: 116

: In the brain, acetylcholine (ACh) is regarded as one of the major neurotransmitters. During the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to extensive cognitive dysfunction and decline. Acetylcholinesterase (AChE) remains a highly feasible target for the ...

Health SciencesMedicinePharmacology
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Molecular Mechanisms of Metal Toxicity in the Pathogenesis of Alzheimer’s Disease

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Md. Tanvir Kabir, Md. Sahab Uddin, Sonia Zaman, Yesmin Begum et al.

Journal: Molecular NeurobiologyYear: 2020Citations: 114

Alzheimer's disease (AD) is the most common form of dementia, which is progressively affecting elderly people. The dyshomeostasis of biometals and accumulation of toxic metals are usually observed in numerous neurodegenerative diseases including AD. In the central nervous system, metal imbalance-cau...

Health SciencesNursingNutrition and DieteticsOpen Access
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