Mohitosh Biswas, Most. Sumaiya Khatun Kali
The effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) in the treatment of COVID-19 are highly debated. This study was aimed to assess aggregated risk by investigating the association of ACEIs/ARBs users against non-users of ACEIs/ARBs with the ri...
Mohitosh Biswas, Shawonur Rahaman, Tapash Kumar Biswas, Baharudin Ibrahim
Introduction The effects of the ABCB1 C3435T genetic polymorphism on clopidogrel responses are conflicting and inconclusive especially in patients undergoing percutaneous coronary intervention (PCI). This study examined the pooled risk of major adverse cardiovascular events (MACE) and bleeding event...
Debendra Nath Roy, Md. Mohabbot Hossen, Mohitosh Biswas, Md. Ekramul Islam et al.
<ns3:p> <ns3:bold>Background:</ns3:bold> Examining the prevalence of coronavirus disease (COVID-19) vaccine hesitancy and understanding what motivates students to accept or reject a newly promoted vaccine has the potential in preventing rapid spread of infection and optimizing country-wide mass vacc...
Chalirmporn Atasilp, Mohitosh Biswas, Pimonpan Jinda, Nutthan Nuntharadthanaphong et al.
Effects of UGT1A1*6 and UGT1A1*28 genetic polymorphisms on irinotecan-induced severe toxicities in Asian cancer patients are inconclusive. Also, ABCC2 c.3972C>T may affect toxicity of irinotecan. The aim was to assess the aggregated risk of neutropenia or diarrhea in Asian cancer patients taking iri...
Aktar Uzzaman Chouduri, Mohitosh Biswas, Md Haque, Md Saiful et al.
The study aims to assess the prescribing practices of antibiotics to outpatients attending public-private hospitals in Bangladesh and to investigate how the irrational uses of antibiotics influence the development of antimicrobial resistance in pathogens over time. A cross-sectional survey was condu...
Mohitosh Biswas, Md. Shahadat Hossain, Tahsin Ahmed Rupok, Md. Sabbir Hossain et al.
The aggregated risk of recurrent stroke in stroke/transient ischemic attack (TIA) patients carrying CYP2C19 LoF alleles who take clopidogrel has not been investigated recently, and the available research is limited. This study aimed to perform an updated meta-analysis to assess the association betwe...
Piya Chaemsaithong, Mohitosh Biswas, Waranyu Lertrut, Puntabut Warintaksa et al.
Preeclampsia is a pregnancy-specific disorder, and it is a leading cause of maternal and perinatal morbidity and mortality. The application of pharmacogenetics to antihypertensive agents and dose selection in women with preeclampsia is still in its infancy. No current prescribing guidelines from the...
Kanyawan Tiwattanon, Shobana John, Napatrupron Koomdee, Pimonpan Jinda et al.
Objective: This study aimed to investigate the clinical impact of HLA-B*15:02 pharmacogenomics (PGx) testing before carbamazepine (CBZ)/oxcarbazepine (OXC) prescriptions and to determine whether this PGx testing was associated with the reduction of CBZ/OXC-induced cutaneous adverse drug reactions (C...
Mohitosh Biswas, Shobana John, Pimonpan Jinda, Chonlaphat Sukasem
INTRODUCTION: Azole antifungal drugs are commonly prescribed to treat invasive fungal infections in various disease conditions. However, these drugs are substrates and inhibitors of cytochrome P450 (CYP) enzymes, UGT1A4, and P-gp. The genetic variants of CYP3A4/5, CYP2C9, CYP2C19, ABCB1, or UGT1A4 c...
Mohitosh Biswas, Natchaya Vanwong, Chonlaphat Sukasem
) with risperidone-induced hyperprolactinemia in ASD is also evident from multiple studies. In addition to genetic factors, dose, duration and drug-drug interactions of risperidone might also increase the serum prolactin level. There are several difficulties, such as reimbursement, knowledge and edu...
Mohitosh Biswas, Debendra Nath Roy
AIMS: Hydroxychloroquine (HCQ) is using as a repurposed drug in considerable proportion of COVID-19 patients. However, being a substrate of cytochrome P450 (CYP) enzymes of CYP3A4/5, CYP2C8 and CYP2D6, the safety and efficacy of this drug may be affected by the coadministration of respective CYP inh...
Mohitosh Biswas, Natchaya Vanwong, Chonlaphat Sukasem
Autism spectrum disorder (ASD) may affect family and social life profoundly. Although there is no selective pharmacotherapy for ASD, the Food and Drug Administration (FDA) has recommended risperidone/aripiprazole to treat the associated symptoms of ASD, such as agitation/irritability. Strong associa...
Napatrupron Koomdee, Chiraphat Kloypan, Pimonpan Jinda, Jiratha Rachanakul et al.
Background: The HLA-B is the most polymorphic gene, play a crucial role in drug-induced hypersensitivity reactions. There is a lot of evidence associating several risk alleles to life-threatening adverse drug reactions, and a few of them have been approved as valid biomarkers for predicting life-thr...
Mohitosh Biswas, Shawonur Rahaman, Tapash Kumar Biswas, Zahirul Haque et al.
Background: Evidence for the associations of sex, age and comorbidities on the risk of death and infection caused by 2019-nCoV is not well-established. It was aimed to build a robust evidence by estimating aggregated risk for sex, age and comorbidities on the death and infection cases of COVID-2019....
Debendra Nath Roy, Md. Shah Azam, Mohitosh Biswas, Md. Ekramul Islam
Abstract This study investigated Coronavirus disease 2019 (COVID-19) vaccine acceptance, and compared the potential factors influencing vaccine acceptance and hesitancy between public university (PuU) and private university (PrU) students in Bangladesh. An anonymous, self-administered questionnaire ...