Arif Mohammad Tanmoy, Yogesh Hooda, Mohammad Saiful Islam Sajib, Hafizur Rahman et al.
BACKGROUND: Rising antimicrobial resistance (AMR) in Salmonella Typhi restricts typhoid treatment options, heightening concerns for pan-oral drug-resistant outbreaks. However, lack of long-term temporal surveillance data on AMR in countries with high burden like Bangladesh is scarce. Our study explo...
Mohammad Khaja Mafij Uddin, Md. Fahim Ather, Senjuti Kabir, Arfatur Rahman et al.
Accurate and appropriate extrapulmonary tuberculosis (EPTB) diagnosis remains challenging due to its paucibacillary nature, requirement of invasive collection procedures, and lack of sensitive tests. This study investigated the diagnostic performance of different methods for the diagnosis of EPTB. A...
Senjuti Saha, ASM Nawshad Uddin Ahmed, Probir Kumar Sarkar, Mohammed Rizwanul Ahsan Bipul et al.
BACKGROUND: The impact of SARS-CoV-2 on neonates remains largely unknown in low- and middle-income countries (LMICs). We provide an epidemiologic and clinical report of SARS-CoV-2 infections in neonates hospitalized in Bangladesh. METHODS: Outborn neonates admitted to Dhaka Shishu Hospital, a tertia...
Yogesh Hooda, Shuborno Islam, Rathin Kabiraj, Hafizur Rahman et al.
Typhoid-conjugate vaccines (TCVs) provide an opportunity to reduce the burden of typhoid fever, caused by Salmonella Typhi, in endemic areas. As policymakers design vaccination strategies, accurate and high-resolution data on disease burden is crucial. However, traditional blood culture-based survei...
Mohammad Khaja Mafij Uddin, Md. Fahim Ather, Arfatur Rahman, Rumana Nasrin et al.
Tuberculosis (TB) remains one of the leading causes of death and Bangladesh ranks 7th among the highest TB burden countries. Though molecular epidemiological data for pulmonary TB (PTB) have previously been described in Bangladesh, data on the molecular characterization and clinical association with...
Farjana Chowdhury, Senjuti Pal, Tasnuva Sharmin, Ridwan Bin Rashid et al.
The methanol extracts of leaf of Artocarpus chaplasha Roxb. and Bougainvillea spectabillis Willd. as well as their petroleum ether, carbon tetrachloride, chloroform and aqueous soluble partitionates were subjected to screenings for antioxidant, cytotoxic, thrombolytic, membrane stabilizing and antim...
Senjuti Saha, Sudipta Saha, Naito Kanon, Yogesh Hooda et al.
BACKGROUND: Respiratory syncytial virus (RSV) is a leading cause of paediatric hospital admissions worldwide, straining health systems. A lack of data on the burden of RSV infections and the impact on health systems in resource-limited settings hinders evidence-based policy decisions. Here, we aimed...
Mohammad Saiful Islam Sajib, Arif Mohammad Tanmoy, Yogesh Hooda, Hafizur Rahman et al.
BACKGROUND: Typhoid and paratyphoid remain common bloodstream infections in areas with suboptimal water and sanitation infrastructure. Paratyphoid, caused by Salmonella Paratyphi A, is less prevalent than typhoid and its antimicrobial resistance (AMR) trends are less documented. Empirical treatment ...
Gary L. Darmstadt, Saifuddin Ahmed, Mohammad Shahidul Islam, Safa Abdalla et al.
Background: The World Health Organization (WHO) has developed guidance for community health workers (CHWs) in identifying sick young infants based on clinical signs. We conducted a prospective, observational cohort study to characterise mortality risk of young infants based on their clinical signs. ...
Denise O Garrett, Ashley T Longley, Kristen Aiemjoy, Farah Naz Qamar et al.
Background: Precise enteric fever disease burden data are needed to inform prevention and control measures, including the use of newly available typhoid vaccines. To inform these strategies, the Surveillance for Enteric Fever in Asia Project (SEAP) conducted prospective, facility-based surveillance ...
Md Shajedur Rahman Shawon, Fariha Binte Hossain, Anupama Thabrew, Senjuti Kabir et al.
Sedentary behaviour has become a critical public health issue among adolescents, with growing evidence linking it to adverse mental health outcomes. This study aimed to quantify the prevalence of sedentary behaviour and mental health symptoms among adolescents and explore their associations using da...
Senjuti Rahman, Md. Mehedi Hasan, Ajay Krishno Sarkar
Heart plays a crucial role in all forms of life. Heart-related disorders demand higher precision, consistency, and accuracy in diagnosis and prognosis because even a small mistake might lead to death. Heart-related deaths are common, and the number of these deaths is rising rapidly day by day. Heart...
Roly Malaker, Md Hasanuzzaman, Yogesh Hooda, Hafizur Rahman et al.
The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced in March 2015 in Bangladesh. In this study, we aimed to estimate the impact of PCV10 on invasive pneumococcal disease (IPD) identified by blood cultures and severe pneumonia identified clinically and its effectiveness on invasive di...
Yogesh Hooda, Arif Mohammad Tanmoy, Sudipta Deb Nath, Anannya Barman Jui et al.
gene on the pCROB1 plasmid. This genotype-plasmid lineage represents a recent introduction, calling for strengthened surveillance, antimicrobial stewardship, and vaccination strategies.
S. M. Mazidur Rahman, Rumana Nasrin, Senjuti Kabir, Faisal Kabir et al.
Rapid and reliable diagnostic tests for tuberculous meningitis (TBM) in children remain limited. This study evaluated the performance of Xpert MTB/RIF Ultra (Ultra), an improved version of Xpert MTB/RIF (Xpert), for detecting TBM in children using cerebrospinal fluid (CSF). Children (0-14 years) pre...
Senjuti Saha, Akshaya Ramesh, Katrina Kalantar, Roly Malaker et al.
Abstract The disease burden due to meningitis in low and middle-income countries remains significant and failure to determine an etiology impedes appropriate treatment for patients and evidence-based policy decisions for populations. Broad-range pathogen surveillance using metagenomic next-generatio...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Abstract The Global Typhoid Genomics Consortium was established to bring together the typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks twenty-one years since the publication of the fi...
Senjuti Saha, Naito Kanon, Mohammad Shahidul Islam, Mohamed K. Hassan et al.
Sira Jam Munira, Shiva Ram Naga, Irum Fatima Dehraj, Kate Doyle et al.
Background: . Paratyphi) to provide an evidence base for prevention and control measures in Bangladesh, Nepal, and Pakistan. Methods: From October 2020 to September 2022, we conducted prospective clinical surveillance and retrospective laboratory surveillance at health facilities in Dhaka, Banglades...
Senjuti Kabir, Shuvasish Choudhury, Tanzila Rahman, Sejuti Rahman et al.
INTRODUCTION: MTB/RIF Ultra (Ultra), as recommended by the WHO to improve childhood pulmonary TB (PTB) diagnosis. METHODS: USAID's Alliance for Combating TB in Bangladesh Activity, in collaboration with the National TB Control Programme, is implementing a stool-based diagnostic approach at 51 health...