Balaji Bhavadharini, Viswanathan Mohan, Mahshid Dehghan, Sumathy Rangarajan et al.
OBJECTIVE Previous prospective studies on the association of white rice intake with incident diabetes have shown contradictory results but were conducted in single countries and predominantly in Asia. We report on the association of white rice with risk of diabetes in the multinational Prospective U...
Deepa Mohan, Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan et al.
Importance: Cohort studies report inconsistent associations between fish consumption, a major source of long-chain ω-3 fatty acids, and risk of cardiovascular disease (CVD) and mortality. Whether the associations vary between those with and those without vascular disease is unknown. Objective: To ex...
Ailiana Santosa, Annika Rosengren, Chinthanie Ramasundarahettige, Sumathy Rangarajan et al.
Importance: Stress may increase the risk of cardiovascular disease (CVD). Most studies on stress and CVD have been conducted in high-income Western countries, but whether stress is associated with CVD in other settings has been less well studied. Objective: To investigate the association of a compos...
Sumathi Swaminathan, Mahshid Dehghan, John Michael Raj, Tinku Thomas et al.
OBJECTIVE: To evaluate the association between intakes of refined grains, whole grains, and white rice with cardiovascular disease, total mortality, blood lipids, and blood pressure in the Prospective Urban and Rural Epidemiology (PURE) study. DESIGN: Prospective cohort study. SETTING: PURE study in...
Martin O’Donnell, Andrew Mente, Sumathy Rangarajan, Matthew McQueen et al.
OBJECTIVE: To evaluate the joint association of sodium and potassium urinary excretion (as surrogate measures of intake) with cardiovascular events and mortality, in the context of current World Health Organization recommendations for daily intake (<2.0 g sodium, >3.5 g potassium) in adults. DESIGN:...
Sidong Li, Scott A. Lear, Sumathy Rangarajan, Bo Hu et al.
Importance: High amounts of sitting time are associated with increased risks of cardiovascular disease (CVD) and mortality in high-income countries, but it is unknown whether risks also increase in low- and middle-income countries. Objective: To investigate the association of sitting time with morta...
Clara K Chow, Tu Ngoc Nguyen, Simone Marschner, Rafael Díaz et al.
OBJECTIVES: We aimed to examine the relationship between access to medicine for cardiovascular disease (CVD) and major adverse cardiovascular events (MACEs) among people at high risk of CVD in high-income countries (HICs), upper and lower middle-income countries (UMICs, LMICs) and low-income countri...
Ryo Naito, Darryl P. Leong, Shrikant I. Bangdiwala, Martin McKee et al.
OBJECTIVE: To examine the association between social isolation and mortality and incident diseases in middle-aged adults in urban and rural communities from high-income, middle-income and low-income countries. DESIGN: Population-based prospective observational study. SETTING: Urban and rural communi...
Benjamin Palafox, Martin McKee, Dina Balabanova, Khalid F. AlHabib et al.
BACKGROUND: Effective policies to control hypertension require an understanding of its distribution in the population and the barriers people face along the pathway from detection through to treatment and control. One key factor is household wealth, which may enable or limit a household's ability to...
Adrianna Murphy, Benjamin Palafox, Owen O’Donnell, David Stückler et al.
BACKGROUND: There is little evidence on the use of secondary prevention medicines for cardiovascular disease by socioeconomic groups in countries at different levels of economic development. METHODS: We assessed use of antiplatelet, cholesterol, and blood-pressure-lowering drugs in 8492 individuals ...
Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan, Viswanathan Mohan et al.
BACKGROUND Eggs are a rich source of essential nutrients, but they are also a source of dietary cholesterol. Therefore, some guidelines recommend limiting egg consumption. However, there is contradictory evidence on the impact of eggs on diseases, largely based on studies conducted in high-income co...
Romaina Iqbal, Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan et al.
BACKGROUND Dietary guidelines recommend limiting red meat intake because it is a major source of medium- and long-chain SFAs and is presumed to increase the risk of cardiovascular disease (CVD). Evidence of an association between unprocessed red meat intake and CVD is inconsistent. OBJECTIVE The stu...
Philip Joseph, Salim Yusuf, Shun Fu Lee, Quazi Ibrahim et al.
OBJECTIVE: To evaluate the performance of the non-laboratory INTERHEART risk score (NL-IHRS) to predict incident cardiovascular disease (CVD) across seven major geographic regions of the world. The secondary objective was to evaluate the performance of the fasting cholesterol-based IHRS (FC-IHRS). M...
MyLinh Duong, Shofiqul Islam, Sumathy Rangarajan, Koon Teo et al.
Background Despite the rising burden of chronic respiratory diseases, global data for lung function are not available. We investigated global variation in lung function in healthy populations by region to establish whether regional factors contribute to lung function. Methods In an international, co...
Kwadwo Boakye, Marit L. Bovbjerg, John M. Schuna, Adam J. Branscum et al.
Urbanization may influence physical activity (PA) levels, although little evidence is available for low- and middle- income countries where urbanization is occurring fastest. We evaluated associations between urbanization and total PA, as well as work-, leisure-, home-, and transport-specific PA, fo...