Mohasana Afroz, S. M. Neamul Kabir Zihad, Shaikh Jamal Uddin, Razina Rouf et al.
Traditionally, sesame oil (SO) has been used as a popular food and medicine. The review aims to summarize the antioxidant and antiinflammatory effects of SO and its identified compounds as well as further fatty acid profiling and molecular docking study to correlate the interaction of its identified...
Meher Afroz, Md. Shimul Bhuia, Md. Anisur Rahman, Rubel Hasan et al.
Piperine is a natural alkaloid that possesses a variety of therapeutic properties, including anti-inflammatory, antioxidant, antibacterial, and anticarcinogenic activities. The present study aims to assess the medicinal benefits of piperine as an anti-diarrheal agent in a chick model by utilizing in...
Rasel Ahmed Khan, Rajib Hossain, Pranta Roy, Divya Jain et al.
Cancer, the uncontrolled proliferation and metastasis of abnormal cells, is a major public health issue worldwide. To date, several natural compounds have been reported with their efficacy in the treatment of different types of cancer. Chemotherapeutic agents are used in cancer treatment and prevent...
Muhammad Torequl Islam, Cristina Quispe, Dina M. El‐Kersh, Manik Chandra Shill et al.
Benincasa hispida (Thunb.) Cogn. (Cucurbitaceae) is an annual climbing plant, native to Asia with multiple therapeutic uses in traditional medicine. This updated review is aimed at discussing the ethnopharmacological, phytochemical, pharmacological properties, and molecular mechanisms highlighted in...
Rubel Hasan, Abdulrahman Alshammari, Norah A. Albekairi, Md. Shimul Bhuia et al.
Abstract The present study was designed to evaluate the antiemetic activity of abietic acid (AA) using in vivo and in silico studies. To assess the effect, doses of 50 mg/kg b.w. copper sulfate (CuSO 4 ⋅5H 2 O) were given orally to 2-day-old chicks. The test compound (AA) was given orally at two dos...
Muhammad Torequl Islam
PURPOSE: The use of radiation, especially ionizing radiation (IR), is currently attracting great attention in the field of medical sciences. However, it should be mentioned that IR has both beneficial and harmful effects in biological systems. This review aims to focus on IR-mediated physiological e...
Eunüs S. Ali, Shamima Akter, Sarker Ramproshad, Banani Mondal et al.
MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase) pathway is an important link in the transition from extracellular signals to intracellular responses. Because of genetic and epigenetic changes, signaling cascades are altered in a variety of diseases, including c...
Rasel Ahmed Khan, Rajib Hossain, Abolghasem Siyadatpanah, Khattab Al-Khafaji et al.
Dengue fever is a dangerous infectious endemic disease that affects over 100 nations worldwide, from Africa to the Western Pacific, and is caused by the dengue virus, which is transmitted to humans by an insect bite of Aedes aegypti. Millions of citizens have died as a result of dengue fever and den...
Muhammad Torequl Islam, Cristina Quispe, Miquel Martorell, Anca Oana Docea et al.
The novel coronavirus (SARS-CoV-2) causing COVID-19 disease pandemic has infected millions of people and caused more than thousands of deaths in many countries across the world. The number of infected cases is increasing day by day. Unfortunately, we do not have a vaccine and specific treatment for ...
Raihan Chowdhury, Md. Shimul Bhuia, Md. Sakib Al Hasan, Siddique Akber Ansari et al.
This study aimed to investigate the anticonvulsant effects of citronellal (CIT) and possible underlying mechanisms through an isoniazid (INH)-induced seizure (convulsion) via in vivo and in silico studies. For this, convulsions were induced by the oral administration of INH (300 mg/kg) to the mice. ...
Md. Shimul Bhuia, Md. Rokonuzzman, Md. Imran Hossain, Siddique Akber Ansari et al.
Numerous previous studies reported that ferulic acid exerts anxiolytic activity. However, the mechanisms have yet to be elucidated. The current study aimed to investigate the anxiolytic effect of trans-ferulic acid (TFA), a stereoisomer of ferulic acid, and evaluated its underlying mechanism using i...
Md. Shimul Bhuia, Hossam Kamli, Tawhida Islam, Fatema Akter Sonia et al.
Current study was conducted to assess the effectiveness of the polyphenol trans-ferulic acid (TFA) as an antiemetic agent using in vivo and in silico methods. To evaluate this, we induced emesis in 3-day-old chicks through the oral administration of copper sulfate (CuSO4·5H2O) at a dose of 50 mg/kg....
Muhammad Torequl Islam, Md. Roich Khan, Siddhartha Kumar Mishra
Muhammad Torequl Islam, Letícia Streck, Marcus Vinícius Oliveira Barros de Alencar, Samara Wanessa Cardoso Silva et al.
Phytol (PYT) is a diterpenoid having important biological activity. However, it is a water non-soluble compound. This study aims to prepare PYT nanoemulsion (PNE) and evaluation of toxic, cytotoxic and genotoxic activities of PYT and PNE. For this, the PNE was prepared by the phase inversion method....
Md. Shimul Bhuia, Polrat Wilairatana, Jannatul Ferdous, Raihan Chowdhury et al.
Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to treat various diseases and ailments. These food items are prominent sources of phytochemicals that exhibit chemopreventive and therapeutic effects against several diseases. Hirsutine (HSN) is a naturally occ...