Mohamed Bnouham, Abdelkhaleq Legssyer, Hassane Mekhfi, Abderrahim Ziyyat
The present review shows a listing of medicinal plants used in phytotherapy of diabetes and those experimentally studied as hypoglycaemic in Morocco. The review is presented as 3 tables. The first one includes the taxonomic classification of the plant, the popular names in Morocco, the parts used, t...
M. Haouari, Mohamed Bnouham, Mourad Bendahou, Mohammed Aziz et al.
Platelet hyperactivity plays an important role in arterial thrombosis and atherosclerosis. The present study was undertaken to investigate the effects of different extracts of Urtica dioica leaves on platelet aggregation. Rat platelets were prepared and incubated in vitro with different concentratio...
Zineb Hakkou, Alexandre Maciuk, Véronique Leblais, Nour Elhouda Bouanani et al.
Background Inula viscosa L. (Asteraceae) is a medicinal plant widely used as a folk medicine in oriental Morocco, to treat hypertension. The antihypertensive effect of the methanolic extract obtained from I. viscosa leaves was evaluated in hypertensive L-NAME rats. Systolic blood pressure (SBP) was ...
Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham et al.
Urtica dioica L. or Nettle (Urticaceae) is widely used in oriental Morocco to treat hypertension. Aqueous extract of Nettle (AEN) also exerts a hypotensive action in the rat in vivo. The aim of this work was to characterize the specific cardiac and vascular effects of AEN. In the isolated Langendorf...
Dounia Gadi, Mohamed Bnouham, Mohammed Aziz, Abderrahim Ziyyat et al.
INTRODUCTION: Blood platelets are directly involved in both haemostatic and pathologic thrombotic processes, through their adhesion, secretion and aggregation. In this study, we investigated the effect of genins (aglycone flavonoids without sugar group) isolated from parsley (Petroselinum crispum) l...
Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham et al.
This study examined the vascular effect of Arbutus leaves (aqueous extract) and described the isolation of several fractions responsible for their vasorelaxant activity. The aqueous extract (AE) of leaves was tested on rat aortic rings precontracted with 0.1 microm noradrenaline. At 10(-2) g/L, AE p...
Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham, Abdelhafid Tahri et al.
Arbutus unedo L. (Ericaceae) is used in oriental Morocco to treat arterial hypertension. We studied its vasodilator effect and mechanisms of action in vitro. The root aqueous extract of Arbutus (0.25 mg/mL) produced a relaxation of noradrenaline-precontracted ring preparations of rat aorta with inta...
Abderrahim Ziyyat, Noureddine Ramdani, Nour El Houda Bouanani, Jean Vanderpas et al.
The major objectives of this work are to estimate the hypertension (HT) frequency in the east of Morocco and to study the relationship between HT, type 2 diabetes and obesity. Our sample is composed of 1628 adults aged 40 years and older, recruited voluntarily by using the convenience sampling metho...
Ahmed Karim, Mohammed Berrabah, Hassane Mekhfi, Abderrahim Ziyyat et al.
The aim of the present study is to determine the chemical composition of the essential oil extracted from the flowers of Anthemis mauritiana Maire & Sennen (EOAM) and to investigate its antispasmodic effects on intestinal smooth muscle. The phytochemical composition was revealed by gas chromatograph...
Mohammad R. Kayes, Supriyo Saha, Mohammed M. Alanazi, Yasuhiro Ozeki et al.
Macromolecules i.e., carbohydrate derivatives are crucial to biochemical and medical research. Herein, we designed and synthesized eight methyl α-D-glucopyranoside (MGP) derivatives (2-8) in good yields following the regioselective direct acylation method. The structural configurations of the synthe...
Noureddine Ramdani, Jean Vanderpas, Abdeslam Boutayeb, Abdelouafi Meziane et al.
Mounia Skiker, Hassane Mekhfi, Mohammed Aziz, Benyounès Haloui et al.
Artemisia herba-alba Asso (Compositae) is used in oriental Morocco to treat diabetes and arterial hypertension. The present work evaluated the vasorelaxant effect of Artemisia herba-alba aqueous extract (AHAE) in isolated rat aorta and the mechanism underlying this effect. In endothelium-containing ...
Amal Elrherabi, Mohamed Bouhrim, Rhizlan Abdnim, Ali Berraaouan et al.
BACKGROUND: Diabetes mellitus is a widespread metabolic disorder affecting global populations. Lavandula stoechas from Moroccan traditional medicine is used for its potential anti-diabetic effects. OBJECTIVE: This study aims to evaluate the antihyperglycemic impact of the aqueous extract of L. stoec...
Hamid Nouayti, Nourel Houda Bouanani, Jamila Hammoudi, Hassane Mekhfi et al.
BACKGROUND Overweight and obesity in children and adolescents have become a major public health problem affecting most countries worldwide. The purpose of the study was to assess the prevalence and risk factors of overweight and obesity among public high school students in Eastern Morocco. METHODS A...
Jamila Hammoudi, Nour El Houda Bouanani, El Habri Chelqi, Y. Bentata et al.
Diabetes is a major cause of morbidity and mortality worldwide. It can affect many organs and, over time, leads to serious complications. Diabetic retinopathy (DR), a specific ocular complication of diabetes, remains the leading cause of vision loss and vision impairment in adults. This work is the ...