Mohammad Forhad Khan, Faisal Bin Kader, Mohammad Arman, Suhel Ahmed et al.
Dita bark (Alstonia scholaris (L.) R. Br.) is an ethnomedicine used for the management of various ailments. This study aimed to investigate the biological properties of methanol extract of A. scholaris bark (MEAS), through in vivo, in vitro and in silico approaches alongside its phytochemical profil...
Mahmudul Hasan, Kazi Faizul Azim, Aklima Begum, Noushin Anika Khan et al.
Marburg virus is known to cause a severe hemorrhagic fever (MHF) in both humans and non-human primates with high degree of infectivity and lethality. To date no approved treatment is available for Marburg virus infection. A study was employed to design a novel chimeric subunit vaccine against Marbur...
Mahmudul Hasan, Md Sorwer Alam Parvez, Kazi Faizul Azim, Md. Abdus Shukur Imran et al.
Here, drug repurposing and molecular docking were employed to screen approved MPP inhibitors and their derivatives to suggest a specific therapeutic agent for the treatment of COVID-19. The approved MPP inhibitors against HIV and HCV were prioritized, while RNA dependent RNA Polymerase (RdRp) inhibi...
Mahmudul Hasan, Kazi Faizul Azim, Md. Abdus Shukur Imran, Ishtiak Malique Chowdhury et al.
Multidrug-resistant Vibrio parahaemolyticus has become a significant public health concern. The development of effective drugs and vaccines against Vibrio parahaemolyticus is the current research priority. Thus, we aimed to find out effective drug and vaccine targets using a comprehensive genome-bas...
Milad Ahmed, Foeaz Ahmed, Jamil Ahmed, Mst Rubaiat Nazneen Akhand et al.
including functional annotation of specific gene targets. Expressed Sequence Tags (ESTs) based homology search of 3350 known miRNAs of dicotyledons were allowed against 763 non-redundant ESTs of jute genome, resulted in the prediction of 5 potential miRNA candidates belonging five different miRNA fa...
Md Bashir Uddin, Mahmudul Hasan, Ahmed Harun‐Al‐Rashid, Md. Irtija Ahsan et al.
SARS-CoV-2, a new coronavirus strain responsible for COVID-19, has emerged in Wuhan City, China, and continuing its global pandemic nature. The availability of the complete gene sequences of the virus helps to know about the origin and molecular characteristics of this virus. In the present study, w...
Syeda Farjana Hoque, Md. Nazmul Islam Bappy, Anjum Taiebah Chowdhury, Md Sorwer Alam Parvez et al.
Abstract Monkeypox is a zoonotic disease caused by monkeypox virus with noteworthy mortality and morbidity. Several recent outbreaks and the need of dependable reconnaissance have raised the level of concern for this developing zoonosis. In the present study, a reverse vaccinology strategy was devel...
Mahmudul Hasan, Md. Abdus Shukur Imran, Farhana Rumzum Bhuiyan, Sheikh Rashel Ahmed et al.
Abstract Seaweeds are able to produce a great variety of secondary metabolites that are characterized by a broad spectrum of biological activities. Two seaweeds species, namely Hypnea musciformis and Enteromorpha intestinalis were studied to evaluate the phytochemical constituency and antimicrobial ...
Md. Abdus Shukur Imran, Farhana Rumzum Bhuiyan, Sheikh Rashel Ahmed, Parsha Shanzana et al.
Seaweeds are able to produce a great variety of secondary metabolites that are characterized by a broad spectrum of biological activities. Two seaweeds species, namely Hypnea musciformis and Enteromorpha intestinalis were studied to evaluate the phytochemical constituency and antimicrobial activitie...
Md Bashir Uddin, Mahmudul Hasan, Ahmed Harun‐Al‐Rashid, Md. Irtija Ahsan et al.
Abstract Recently a new coronavirus strain, COVID-19 has emerged in Wuhan City, China which cause disease and in many cases deaths to humans. Considering its severity a number of works are working on it and full genomic sequences has already released in the last few weeks to understand the evolution...
Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Md. Abdus Shukur Imran, Mst Rubaiat Nazneen Akhand et al.
Emerging multidrug‐resistant (MDR) strains are the main challenges to the progression of new drug discovery. To diminish infectious disease–causing pathogens, new antibiotics are required while the drying pipeline of potent antibiotics is adding to the severity. Plant secondary metabolites or phytoc...
Mahmudul Hasan, Kazi Faizul Azim, Abdus Shukur Imran, Ishtiak Malique Chowdhury et al.
Abstract Multidrug-resistant Vibrio parahaemolyticus has become a significant threat to human health as well as aquaculture, prioritizing the development of effective drug and vaccine candidates. Hence, the study was designed to identify novel therapeutics using a comprehensive genome-based analysis...
Mahmudul Hasan, Md Sorwer Alam Parvez, Kazi Faizul Azim, Md. Abdus Shukur Imran et al.
<div>The world is facing an unprecedented global pandemic caused by the novel SARS-CoV-2. In the absence</div><div>of a specific therapeutic agent to treat COVID-19 patients, the present study aimed to virtually screen out</div><div>the effective drug candidates from th...
Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Md. Abdus Shukur Imran, Mst Rubaiat Nazneen Akhand et al.
Mahmudul Hasan, Md Sorwer Alam Parvez, Kazi Faizul Azim, Md. Abdus Shukur Imran et al.
The world is facing an unprecedented global pandemic caused by the novel SARS-CoV-2. In the absence of a specific therapeutic agent to treat COVID-19 patients, the present study aimed to virtually screen out the effective drug candidates from the approved main protease protein (MPP) inhibitors and t...