Olivo Miotto, Roberto Amato, Elizabeth A. Ashley, Bronwyn MacInnis et al.
We report a large multicenter genome-wide association study of Plasmodium falciparum resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast Asia, we identified at least 20 mutations in kelch13 (PF3D7_1343700) affecting the encoded propeller and BTB/POZ domains, ...
Sachel Mok, Elizabeth A. Ashley, Pedro Eduardo Ferreira, Lei Zhu et al.
Artemisinin resistance in Plasmodium falciparum threatens global efforts to control and eliminate malaria. Polymorphisms in the kelch domain-carrying protein K13 are associated with artemisinin resistance, but the underlying molecular mechanisms are unknown. We analyzed the in vivo transcriptomes of...
Kyaw Myo Tun, Mallika Imwong, Khin Maung Lwin, Aye Aye Win et al.
BACKGROUND: Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Discovery of the K13 marker has transformed approaches to the monitoring of artemisinin resistance, allowing introduction of molecular surveillance in remo...
Rob W. van der Pluijm, Rupam Tripura, Richard M. Hoglund, Aung Pyae Phyo et al.
BACKGROUND: Artemisinin and partner-drug resistance in Plasmodium falciparum are major threats to malaria control and elimination. Triple artemisinin-based combination therapies (TACTs), which combine existing co-formulated ACTs with a second partner drug that is slowly eliminated, might provide eff...
Abul K. Mallik, Md. Abdul Moktadir, Md. Ashiqur Rahman, Md. Shahruzzaman et al.
Various toxic chemicals are discharging to the environment due to rapid industrialization and polluting soil, water, and air causing numerous diseases including life-threatening cancer. Among these pollutants, Cr(VI) or hexavalent chromium is one of the most carcinogenic and toxic contaminants hosti...
Abul K. Mallik, SM Fijul Kabir, Fahim Bin Abdur Rahman, Mohammad Nazmus Sakib et al.
Daniel H. Paris, Mallika Imwong, Abul Faiz, Mahtabuddin Hasan et al.
A recently described loop-mediated isothermal polymerase chain reaction (LAMP) for molecular detection of Plasmodium falciparum was compared with microscopy, PfHRP2-based rapid diagnostic test (RDT), and nested polymerase chain reaction (PCR) as the "gold standard" in 115 Bangladeshi in-patients wit...
Md. Nazrul Islam, M. Nuruzzaman Khan, Abul K. Mallik, Mohammed Mizanur Rahman
Chitosan and poly(1-vinylimidazole) are both potential adsorbents to remove Cr(VI). Here, we designed the preparation of new adsorbents by combining chitosan and poly(1-vinylimidazole) to get the synergistic effect for the removal of hexavalent chromium. Trimethoxysilyl group terminated poly(1-vinyl...
Lei Zhu, Rob W. van der Pluijm, Michal Kucharski, Sourav Nayak et al.
The emergence and spread of artemisinin-resistant Plasmodium falciparum, first in the Greater Mekong Subregion (GMS), and now in East Africa, is a major threat to global malaria elimination ambitions. To investigate the artemisinin resistance mechanism, transcriptome analysis was conducted of 577 P....
Mohammed Mizanur Rahman, Abul K. Mallik, Mubarak A. Khan
Abstract Natural‐fiber‐reinforced polymers can exhibit very different mechanical performances and environmental aging resistance depending on their interphase properties. A lack of good interfacial adhesion and poor resistance to moisture absorption make oil palm fibers less attractive as reinforcin...
Farzana Yeasmin, Abul K. Mallik, Adib H. Chisty, Fataha Nur Robel et al.
For the first time, we incorporated mesoporous micro-silica (5 μm, pore size = 50 nm) as a filler in epoxy resin aiming to enter polymer into the pore of the silica. As expected, the thermal stability of the composite increased remarkably, followed by noteworthy thermal degradation kinetics when com...
Mohammad Nazmus Sakib, Abul K. Mallik, Mohammed Mizanur Rahman
Now-a-days water pollution is one of the most concerned problem as it is increasing due to industrialization and human activities. The applications of electrospun nanofibers are increasing day by day due to their special properties such as huge surface-to-volume ratio, possibilities of surface modif...
S.M. Sultan Mahmud Rahat, Khan Md. Zubaed Hasan, Muhammad Abdul Mojid Mondol, Abul K. Mallik
Md. Sazedul Islam, Papia Haque, Taslim Ur Rashid, M. Nuruzzaman Khan et al.
A multifunctional drug carrier with dual targeting (magnetic and folate-receptor) and pH sensitive core-shell hybrid nanomaterial has been developed to carry an anticancer drug doxorubicin.Superparamagnetic iron oxide nanoparticles (IONPs) were used as core of the carrier and cross-linked folate con...
Abul K. Mallik, Hongdeng Qiu, Makoto Takafuji, Hirotaka Ihara
Reversed-phase liquid chromatography (RPLC) is the most popular separation mode in high-performance liquid chromatography (HPLC). The design and synthesis of new separation materials to meet growing demands has always been a major concern to enhance the selectivity of stationary phases. Therefore, v...