James A Platts-Mills, Jie Liu, Elizabeth T. Rogawski McQuade, Furqan Kabir et al.
BACKGROUND: Optimum management of childhood diarrhoea in low-resource settings has been hampered by insufficient data on aetiology, burden, and associated clinical characteristics. We used quantitative diagnostic methods to reassess and refine estimates of diarrhoea aetiology from the Etiology, Risk...
Elizabeth T. Rogawski McQuade, Jie Liu, James A Platts-Mills, Furqan Kabir et al.
BACKGROUND: Enteropathogen infections in early childhood not only cause diarrhoea but contribute to poor growth. We used molecular diagnostics to assess whether particular enteropathogens were associated with linear growth across seven low-resource settings. METHODS: We used quantitative PCR to dete...
Caroline Amour, Jean Gratz, Estomih Mduma, Erling Svensen et al.
BACKGROUND: Enteropathogen infections have been associated with enteric dysfunction and impaired growth in children in low-resource settings. In a multisite birth cohort study (MAL-ED), we describe the epidemiology and impact of Campylobacter infection in the first 2 years of life. METHODS: Children...
Anthony D. Okely, Katharina E. Kariippanon, Hongyan Guan, Ellie Taylor et al.
BACKGROUND: The restrictions associated with the 2020 COVID-19 pandemic has resulted in changes to young children's daily routines and habits. The impact on their participation in movement behaviours (physical activity, sedentary screen time and sleep) is unknown. This international longitudinal stu...
Josh M. Colston, Tahmeed Ahmed, Tjale Cloupas Mahopo, Gagandeep Kang et al.
BACKGROUND: Longitudinal and time series analyses are needed to characterize the associations between hydrometeorological parameters and health outcomes. Earth Observation (EO) climate data products derived from satellites and global model-based reanalysis have the potential to be used as surrogates...
Crystal L. Patil, Ali Turab, Ramya Ambikapathi, Cebisa Noxolo Nesamvuni et al.
We report the infant feeding experiences in the first month of life for 2,053 infants participating in "Malnutrition and Enteric Infections: Consequences for Child Health and Development" (MAL-ED). Eight sites (in Bangladesh, India, Nepal, Pakistan, Brazil, Peru, South Africa, Tanzania), each follow...
Anthony D. Okely, John J. Reilly, Mark S. Tremblay, Katharina E. Kariippanon et al.
Introduction 24-hour movement behaviours (physical activity, sedentary behaviour and sleep) during the early years are associated with health and developmental outcomes, prompting the WHO to develop Global guidelines for physical activity, sedentary behaviour and sleep for children under 5 years of ...
Elizabeth T. Rogawski McQuade, Fariha Shaheen, Furqan Kabir, Arjumand Rizvi et al.
Culture-independent diagnostics have revealed a larger burden of Shigella among children in low-resource settings than previously recognized. We further characterized the epidemiology of Shigella in the first two years of life in a multisite birth cohort. We tested 41,405 diarrheal and monthly non-d...
Laura E. Caulfield, Anuradha Bose, Ram K. Chandyo, Cebisa Noxolo Nesamvuni et al.
The overall goal of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study is to evaluate the roles of repeated enteric infection and poor dietary intakes on the development of malnutrition, poor ...
Kar Hau Chong, Thomas Suesse, Penny Cross, Sarah T. Ryan et al.
Importance: The prevalence estimates of physical activity, sedentary behavior, and sleep (collectively known as movement behaviors) in 3- and 4-year-old children worldwide remains uncertain. Objective: To report the proportion of 3- and 4-year-old children who met the World Health Organization guide...
Benjamin McCormick, Laura E. Murray‐Kolb, Gwenyth O. Lee, Kerry Schulze et al.
BACKGROUND: Environmental enteric dysfunction (EED) is thought to increase the risk of micronutrient deficiencies, but few studies adjust for dietary intakes and systemic inflammation. OBJECTIVE: We tested whether EED is associated with micronutrient deficiency risk independent of diet and systemic ...
Josh M. Colston, Benjamin F. Zaitchik, Gagandeep Kang, Pablo Peñataro Yori et al.
BackgroundClimate change threatens to undermine recent progress in reducing global deaths from diarrhoeal disease in children. However, the scarcity of evidence about how individual environmental factors affect transmission of specific pathogens makes prediction of trends under different climate sce...
Ramya Ambikapathi, Margaret Kosek, Gwenyth O. Lee, Tjale Cloupas Mahopo et al.
Abstract The duration of exclusive breastfeeding (EBF) is often defined as the time from birth to the first non‐breast milk food/liquid fed (EBFLONG), or it is estimated by calculating the proportion of women at a given infant age who EBF in the previous 24 h (EBFDHS). Others have measured the total...
Stephanie A Richard, Benjamin McCormick, Jessica C. Seidman, Zeba Rasmussen et al.
Children in low-income countries experience multiple illness symptoms in early childhood. Breastfeeding is protective against diarrhea and respiratory infections, and these illnesses are thought to be risk factors of one another, but these relationships have not been explored simultaneously. In the ...
Muhammad Hammad, Md Shamimul Islam, Mohammad Asif Salam, Ali Turab Jafry et al.
Smart manufacturing has become a vital technique for increasing productivity and efficiency. Firms are following a smart manufacturing implementation system to compete in the market. Therefore, it is mandatory to find the crucial factors that enable the implementation of intelligent manufacturing in...
Josh M. Colston, Akhter Ahmed, Sajid Soofi, Erling Svensen et al.
Improving understanding of the pathogen-specific seasonality of enteric infections is critical to informing policy on the timing of preventive measures and to forecast trends in the burden of diarrhoeal disease. Data obtained from active surveillance of cohorts can capture the underlying infection s...
Md. Mahfuzur Rahman, Md. Turab Haque Payel, Md. Asaduzzaman, Sajid Hossain et al.
Abstract Cellulose, a naturally abundant biopolymer, holds great potential as a sustainable alternative to synthetic fibers. However, the limited understanding and awareness surrounding cellulose utilization, particularly from agricultural origins, have impeded the complete harnessing of this highly...
DA Antiporta, Ramya Ambikapathi, Anuradha Bose, Bruna Leal Lima Maciel et al.
OBJECTIVE: To estimate the total energy and micronutrient intakes of children 9-24 months of age and evaluate the probability of adequacy (PA) of the diet in seven MAL-ED sites. DESIGN: Cohort study. Food intake was registered monthly using 24-h recalls beginning at 9 months. We estimated PA for thi...
Zhiguang Zhang, Chalchisa Abdeta, Mohamed Souhaiel Chelly, Jesús del Pozo-Cruz et al.
STUDY OBJECTIVES: To examine (1) multidimensional sleep profiles in preschoolers (3-6 years) across geocultural regions and (2) differences in sleep characteristics and family practices between Majority World regions (Pacific Islands, Sub-Saharan Africa, Eastern Europe, Northeast Asia, Southeast Asi...
Stephanie A. Richard, Benjamin McCormick, Laura E. Murray‐Kolb, Pascal Bessong et al.
BACKGROUND: Poor growth in early childhood has been considered irreversible after 2-3 years of age and has been associated with morbidity and mortality over the short-term and with poor economic and cognitive outcomes over the long-term. The MAL-ED cohort study was performed in eight low-income sett...