Naïma Madi, Emilee Cato, Md. Abu Sayeed, Ashton Creasy-Marrazzo et al.
Despite an increasingly detailed picture of the molecular mechanisms of bacteriophage (phage)–bacterial interactions, we lack an understanding of how these interactions evolve and impact disease within patients. In this work, we report a year-long, nationwide study of diarrheal disease patients in B...
Aline Cuénod, Denise Chac, Ashraful Islam Khan, Fahima Chowdhury et al.
Two circular chromosomes are a defining feature of the bacterial family Vibrionaceae, including the pathogen Vibrio cholerae, with rare reports of isolates with a single, fused chromosome. Here, we use long-read sequencing to analyse 467 V. cholerae O1 isolates from 47 cholera patients and household...
Naïma Madi, Emilee Cato, Md. Abu Sayeed, Ashton Creasy-Marrazzo et al.
Abstract Despite an increasingly detailed picture of the molecular mechanisms of phage-bacterial interactions, we lack an understanding of how these interactions evolve and impact disease within patients. Here we report a year-long, nation-wide study of diarrheal disease patients in Bangladesh. Amon...
Chuhan Qin, Patrick Lypaczewski, Md. Abu Sayeed, Aline Cuénod et al.
Cholera is an acute diarrhoeal disease caused by Vibrio cholerae . It remains a major public health challenge worldwide, and particularly in the endemic region around the Bay of Bengal. Over decadal time scales, one lineage typically dominates and spreads in global pandemic waves. However, it remain...
Chuhan Qin, Patrick Lypaczewski, Md. Abu Sayeed, Aline Cuénod et al.
Abstract Cholera is a diarrhoeal disease caused by Vibrio cholerae . It remains a major public health challenge in the endemic region around the Bay of Bengal. Over decadal time scales, one lineage typically dominates the others and spreads in global pandemic waves. However, it remains unclear to wh...
Aline Cuénod, Denise Chac, Ashraful Islam Khan, Fahima Chowdhury et al.
Abstract Two circular chromosomes are a defining feature of the family Vibrionaceae , including the pathogen Vibrio cholerae , with rare reports of isolates with a single, fused chromosome. Here we report chromosome fusions in clinical V. cholerae O1 isolates, including several independent fusion ev...