W. Abdullah Brooks, Anowar Hossain, Doli Goswami, Amina Tahia Sharmeen et al.
We confirmed a bacteremic typhoid fever incidence of 3.9 episodes/1,000 person-years during fever surveillance in a Dhaka urban slum. The relative risk for preschool children compared with older persons was 8.9. Our regression model showed that these children were clinically ill, which suggests a ro...
W. Abdullah Brooks, Khalil Zaman, Kristen Lewis, Justin R. Ortiz et al.
The rates of infl uenza illness and associated complications are high among children in Bangladesh. We assessed the clinical effi cacy and safety of a Russian-backbone live attenuated infl uenza vaccine (LAIV) at two fi eld sites in Bangladesh.
W. Abdullah Brooks, Pauline Terebuh, Carolyn B. Bridges, Alexander Klimov et al.
To the Editor: Influenza A and B viruses are associated with seasonal epidemics (1). Influenza is increasingly recognized as a cause of severe respiratory disease among healthy children in industrialized countries (2–4). However, little information is available from developing countries (5). We a...
W. Abdullah Brooks, Dean D. Erdman, Pauline Terebuh, Alexander Klimov et al.
We confirmed circulation of human metapneumovirus (HMPV) among children with febrile and respiratory illness in an urban slum in Dhaka, Bangladesh, during active surveillance in 2001. HMPV was the most common single virus identified among febrile children and appears to contribute to the high rates ...
Melissa A. Rolfes, Doli Goswami, Amina Tahia Sharmeen, Sultana Yeasmin et al.
BACKGROUND: Few trials have evaluated influenza vaccine efficacy (VE) in young children, a group particularly vulnerable to influenza complications. We aimed to estimate VE against influenza in children aged <2 years in Bangladesh; a subtropical setting, where influenza circulation can be irregular....
Justin R. Ortiz, Doli Goswami, Kristen Lewis, Amina Tahia Sharmeen et al.
INTRODUCTION: Live-attenuated influenza vaccines (LAIVs) have the potential to be affordable, effective, and logistically feasible for immunization of children in low-resource settings. MATERIAL AND METHODS: We conducted a phase II, randomized, double-blind, parallel group, placebo-controlled trial ...
Fatimah S. Dawood, Alicia M. Fry, Doli Goswami, Amina Tahia Sharmeen et al.
BACKGROUND: Early childhood wheezing substantially impacts quality of life in high-income countries, but data are sparse on early childhood wheezing in low-income countries. We estimate wheezing incidence, describe wheezing phenotypes, and explore the contribution of respiratory viral illnesses amon...
Elizabeth Rotrosen, Khalequ Zaman, Jodi Feser, Justin R. Ortiz et al.
BACKGROUND: Influenza causes substantial morbidity in children worldwide, although influenza vaccine is seldom used in low-resource settings. More information on the clinical presentation of influenza and the efficacy of vaccine is needed to inform policy. METHODS: In 2013 we conducted a randomized,...
Prasad S. Kulkarni, Khalequ Zaman, Sajjad Desai, Sandesh Bharati et al.
BACKGROUND Replacing oral polio vaccines with inactivated polio vaccines (IPVs) is necessary to stop the potential transmission of vaccine-derived polio viruses. We aimed to compare the safety and immunogenicity of a dose-sparing IPV (ds-IPV) with a full-dose IPV in infants in Bangladesh. METHODS Th...
Sabeena Ahmed, Mohammad Mahbubul Karim, Ching Swe Phru, Kamrun Nahar et al.
• Reporting seroprevalence of EV71 neutralizing antibodies first time from Bangladesh • High seroprevalence of EV71 neutralizing antibodies among Bangladeshi children • Seropositivity correlated with demographic and socio-economic factors • These findings underscore gaps in research on enterovirus i...
Fiona P. Havers, Alicia M. Fry, Doli Goswami, Kamrun Nahar et al.