Ana Maria B. Menezes, María Montes de, Rogelio Pérez‐Padilla, Gilbert Nadeau et al.
Background Several COPD phenotypes have been described; the COPD-asthma overlap is one of the most recognized. The aim of this study was to evaluate the prevalence of three subgroups (asthma, COPD, and COPD-asthma overlap) in the Latin American Project for the Investigation of Obstructive Lung Disea...
Rosália Maria Tôrres de Lima, Antonielly Campinho dos Reis, Ag‐Anne Pereira Melo de Menezes, José Victor de Oliveira Santos et al.
Natural dietary agents have attracted considerable attention due to their role in promoting health and reducing the risk of diseases including cancer. Ginger, one of the most ancient known spices, contains bioactive compounds with several health benefits. [6]-Gingerol constitutes the most pharmacolo...
Júlia Moreira Pescarini, Agostino Strina, Joilda Silva Nery, Lacita Menezes Skalinski et al.
Over 200,000 new cases of leprosy are detected each year, of which approximately 7% are associated with grade-2 disabilities (G2Ds). For achieving leprosy elimination, one of the main challenges will be targeting higher risk groups within endemic communities. Nevertheless, the socioeconomic risk mar...
Philip H. Quanjer, Gregg L Ruppel, Arnulf Langhammer, Abhishek Krishna et al.
Background Recommendations on interpreting tests of bronchodilator responsiveness (BDR) are conflicting. We investigated the dependence of BDR criteria on sex, age, height, ethnicity, and severity of respiratory impairment. Methods BDR test data were available from clinical patients in the Netherlan...
Ana Maria Baptista Menezes, Fernando C. Wehrmeister, Fernando Pires Hartwig, Rogelio Pérez‐Padilla et al.
African-Americans have smaller lung function compared with European-Americans. The aim of this study was to disentangle the contribution of genetics from other variables on lung function. A cohort was followed from birth to 30 years of age in Brazil. Several variables were collected: genomic analysi...
Juanita A. Haagsma, Periklis Charalampous, Filippo Ariani, Anne Gallay et al.
BACKGROUND: Injury remains a major concern to public health in the European region. Previous iterations of the Global Burden of Disease (GBD) study showed wide variation in injury death and disability adjusted life year (DALY) rates across Europe, indicating injury inequality gaps between sub-region...
Oliver A. Nascimento, Aquiles Assunção Camelier, Fernanda Warken Rosa, Ana Maria Baptista Menezes et al.
Chronic obstructive pulmonary disease (COPD) is a common disease in adults over 40 years of age and has a great social and economic impact. It remains little recognized and undertreated even in developed countries. However, there are no data about its diagnosis and treatment in Brazil. The objective...
Marcia M. Hobbs, M. Steiner, Kimberly D. Rich, Maria Gallo et al.
BACKGROUND: Prostate-specific antigen (PSA) is a valid biomarker of semen exposure in women and has been used to assess reliability of self-reported sexual behavior as well as serve as a proxy measure for condom efficacy. Quantitative PSA tests are expensive and require specialized equipment. A simp...
Rogelio Pérez‐Padilla, Fernando C. Wehrmeister, María Montes de, María Victorina López et al.
BACKGROUND: A low FEV1/FVC from post-bronchodilator spirometry is required to diagnose COPD. Both the FEV1 and the FVC can vary over time; therefore, individuals can be given a diagnosis of mild COPD at one visit, but have normal spirometry during the next appointment, even without an intervention. ...
Antônio Lima Braga, Ag‐Anne Pereira Melo de Menezes, José Victor de Oliveira Santos, Antonielly Campinho dos Reis et al.
Omeprazole (OME) is a proton pump inhibitor used for the treatment of various gastric and intestinal disease; however, studies on its effects on the genetic materials are still restricted. The present study aimed to evaluate possible toxicogenic effects of OME in Allium cepa meristems with the appli...
Jorge Ederson Gonçalves Santana, Cícera Datiane de Morais Oliveira–Tintino, Gabriel Gonçalves Alencar, Gustavo Miguel Siqueira et al.
The efflux systems are considered important mechanisms of bacterial resistance due to their ability to extrude various antibiotics. Several naturally occurring compounds, such as sesquiterpenes, have demonstrated antibacterial activity and the ability to inhibit efflux pumps in resistant strains. Th...
Pieter A. Zuidema, Peter Groenendijk, Mizanur Rahman, Valérie Trouet et al.
Increasing drought pressure under anthropogenic climate change may jeopardize the potential of tropical forests to capture carbon in woody biomass and act as a long-term carbon dioxide sink. To evaluate this risk, we assessed drought impacts in 483 tree-ring chronologies from across the tropics and ...
Vinícius Caldeira Quintão, Cláudia Marquez Simões, Laís Helena Navarro e Lima, Guilherme Antônio Moreira de Barros et al.
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it...
Elba Etchebehere, Rebeca Andrade, Mariana Camacho, Mariana Lima et al.
<sup>18</sup>F-FDG PET/CT quantification of whole-body tumor burden in lymphoma is not routinely performed because of the lack of fast methods. Although the semiautomatic method is fast, it is not fast enough to quantify tumor burden in daily clinical practice. Our purpose was to evaluate the perfor...
Caian L. Vinhaes, Rozana Teixeira, Jay A. S. Monteiro-Júnior, Rafael Tibúrcio et al.
Sickle cell anemia (SCA) is the most common inherited hemolytic anemia worldwide. Here, we performed an exploratory study to investigate the systemic oxidative stress in children and adolescents with SCA. Additionally, we evaluated the potential impact of hydroxyurea therapy on the status of oxidati...