Andrew Nunn, Patrick Phillips, Sarah Meredith, Chen‐Yuan Chiang et al.
BACKGROUND: Cohort studies in Bangladesh showed promising cure rates among patients with multidrug-resistant tuberculosis who received existing drugs in regimens shorter than that recommended by the World Health Organization (WHO) in 2011. METHODS: at 132 weeks and at a previous occasion, with no in...
Patrik Lindenfors, Charles L. Nunn, Kate E. Jones, Andrew A. Cunningham et al.
ABSTRACT Aim Comparative studies have revealed strong links between ecological factors and the number of parasite species harboured by different hosts, but studies of different taxonomic host groups have produced inconsistent results. As a step towards understanding the general patterns of parasite ...
PD Davies, MJ Humphries, S.P. Byfield, Andrew Nunn et al.
Of the 4172 patients in a survey of all cases of tuberculosis notified in a six-month period in England and Wales in 1978-79, 198 had a bone or joint lesion; 79 were white and 108 were of Indian subcontinent (Indian, Pakistani or Bangladeshi) ethnic origin. The estimated annual notification rates fo...
Andrew Nunn, I. D. Rusen, Armand Van Deun, Gabriela Torrea et al.
BACKGROUND: In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated for a minimum of 20 months. A series of cohort ...
Sarah Meredith, V R Aber, Andrew Nunn, DA Johnson et al.
BACKGROUND: A survey was undertaken to determine the distribution of tuberculosis in England and Wales and, by comparison with the findings of similar surveys in 1978-9 and 1983, to study trends in the incidence of the disease by ethnic group over the decade. METHODS: The survey included all cases o...
Andrew Nunn, Janet Darbyshire, W.F. Fox, D A Johnson et al.
In two national surveys of tuberculosis notifications in England conducted in 1978/79 and 1983 the estimated annual notification rates for the Indian subcontinent (Indian, Pakistani, and Bangladeshi) ethnic groups were considerably higher than the rate for the white ethnic group. The mean annual dec...
Wallace Fox, M.J. Humphries, Andrew Nunn, W Fox et al.
The treatment of adult patients, both white and of Indian, Pakistani, or Bangladeshi ethnic origin, with previously untreated pulmonary tuberculosis who were notified in England and Wales from 1 October 1978 to 31 March 1979 has been surveyed. Chemotherapy was completed as planned by the physician i...
L.P. Ormerod, Andrew Nunn, S.P. Byfield, Janet Darbyshire
The pattern of tuberculosis in Indian, Pakistani and Bangladeshi patients in Blackburn (1978-1987) was compared with that for England and Wales (MRC Survey), with particular reference to the proportion with parenchymal lung disease, by a generalized linear model allowing for age, ethnic group and ti...
Chen‐Yuan Chiang, Henry Bern, Ruth Goodall, Shun-Tien Chien et al.
BACKGROUND: Stage 1 of the STREAM trial demonstrated that the 9 month (Short) regimen developed in Bangladesh was non-inferior to the 20 month (Long) 2011 World Health Organization recommended regimen. We assess the association between HIV infection and radiographic manifestations of tuberculosis an...
Andrew Nunn, I. D. Rusen, Armand Van Deun, Gabriela Torrea et al.
Background: \nIn contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant \ntuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are \nthat patients should be treated for a minimum of 20 months. A...
Hanif Esmail, Gopalan Narendran, Andrew Nunn
The management of drug-resistant tuberculosis (DR-TB) has been a formidable challenge for patients, healthcare providers and public health systems for many years. In particular, for multidrug-resistant TB (MDR-TB), resistant to both rifampicin and isoniazid, the available treatments have historicall...