Andrew Nunn, Patrick Phillips, Sarah Meredith, Chen‐Yuan Chiang et al.
BACKGROUND: Cohort studies in Bangladesh showed promising cure rates among patients with multidrug-resistant tuberculosis who received existing drugs in regimens shorter than that recommended by the World Health Organization (WHO) in 2011. METHODS: at 132 weeks and at a previous occasion, with no in...
Daniel Roth, Shaun K. Morris, Stanley Zlotkin, Alison D. Gernand et al.
BACKGROUND: It is unclear whether maternal vitamin D supplementation during pregnancy and lactation improves fetal and infant growth in regions where vitamin D deficiency is common. METHODS: We conducted a randomized, double-blind, placebo-controlled trial in Bangladesh to assess the effects of week...
Alexander van Geen, Habibul Ahsan, A. Horneman, Ratan Dhar et al.
OBJECTIVE: To survey tube wells and households in Araihazar upazila, Bangladesh, to set the stage for a long-term epidemiological study of the consequences of chronic arsenic exposure. METHODS: Water samples and household data were collected over a period of 4 months in 2000 from 4997 contiguous tub...
Nicos Karasavvas, Erik Billings, Mangala Rao, Constance Williams et al.
The Thai Phase III clinical trial (RV144) showed modest efficacy in preventing HIV-1 acquisition. Plasma collected from HIV-1-uninfected trial participants completing all injections with ALVAC-HIV (vCP1521) prime and AIDSVAX B/E boost were tested for antibody responses against HIV-1 gp120 envelope (...
Intza Garin, Emma L. Edghill, İldem Akerman, Oscar Rubio‐Cabezas et al.
Heterozygous coding mutations in the INS gene that encodes preproinsulin were recently shown to be an important cause of permanent neonatal diabetes. These dominantly acting mutations prevent normal folding of proinsulin, which leads to beta-cell death through endoplasmic reticulum stress and apopto...
Xin Lü, David Wrathall, Pål Sundsøy, Md. Nadiruzzaman et al.
Climate change is likely to drive migration from environmentally stressed areas. However quantifying short and long-term movements across large areas is challenging due to difficulties in the collection of highly spatially and temporally resolved human mobility data. In this study we use two dataset...
Mamun Al‐Mahtab, Michel Bazinet, Andrew Vaillant
UNLABELLED: Previous in vivo studies have suggested that nucleic acid polymers (NAPs) may reduce circulating levels of HBsAg in the blood by blocking its release from infected hepatocytes and that this effect may have clinical benefit. NAP treatment, was evaluated in two clinical studies in patients...
Rhoda MacKenzie, A. Paisley, P. L. Allan, Amanda Lee et al.
Purpose Long saphenous vein (LSV) stripping in the treatment of varicose veins may reduce the recurrence of varices but may also increase morbidity rates. The effect of stripping on health-related quality of life (HRQoL) is unknown. The aim of this study was to examine the effect of LSV surgery, wit...
Gaurav Sharma, Matthews Mathai, Kim Dickson, Andrew Weeks et al.
BACKGROUND: Good outcomes during pregnancy and childbirth are related to availability, utilisation and effective implementation of essential interventions for labour and childbirth. The majority of the estimated 289,000 maternal deaths, 2.8 million neonatal deaths and 2.6 million stillbirths every y...
Grace Li, Julia Bielicki, ASM Nawshad Uddin Ahmed, Mohammad Shahidul Islam et al.
OBJECTIVE: To gain an understanding of the variation in available resources and clinical practices between neonatal units (NNUs) in the low-income and middle-income country (LMIC) setting to inform the design of an observational study on the burden of unit-level antimicrobial resistance (AMR). DESIG...
Juana Willumsen, Suzanne Filteau, Andreas Coutsoudis, Kerry Uebel et al.
Subclinical mastitis, as diagnosed by an elevated sodium/potassium ratio in milk accompanied by an increased milk concentration of the inflammatory cytokine, interleukin-8 (IL8), was found to be common among breast feeding women in Bangladesh and Tanzania. Subclinical mastitis results in leakage of ...
Xin Lü, David Wrathall, Pål Sundsøy, Md. Nadiruzzaman et al.
Large-scale data from digital infrastructure, like mobile phone networks, provides rich information on the behavior of millions of people in areas affected by climate stress. Using anonymized data on mobility and calling behavior from 5.1 million Grameenphone users in Barisal Division and Chittagong...
Antonio Leidi, Flora Koegler, Roxane Dumont, Richard Dubos et al.
BACKGROUND: Serological assays detecting anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies are being widely deployed in studies and clinical practice. However, the duration and effectiveness of the protection conferred by the immune response remains to be assessed in popul...
Rhoda MacKenzie, Amanda Lee, A. Paisley, Paul Burns et al.
Background and objective Superficial venous surgery for CEAP 2 disease leads to an improvement in disease-specific quality of life (QoL) in the short term. However, which factors influence the magnitude of this improvement, how surgery affects QoL in patients with CEAP 4 to 6 disease, and whether th...
Anika Rahman, Enamul Huq, A. Jabbar Mian, Andrew Chesson
Trees known to produce two distinct textural forms of jackfruit, in which the fruit either remained firm when ripe or became soft and pulpy, were sampled when fruit was immature (10–11 weeks after anthesis) and when judged ripe (15–16 weeks after anthesis). The dry matter content of the edible peria...