Curly Morris, Christian Chabannon, Tamás Masszi, Nigel H. Russell et al.
Plerixafor plus granulocyte-colony stimulating factor (G-CSF) enhances the mobilization of hematopoietic stem cells (HSCs) for collection and subsequent autologous hematopoietic stem cell transplantation (HSCT) in patients with multiple myeloma (MM). This international, multicenter, noninterventiona...
Firoozeh Sahebi, S. Iacobelli, Anja van Biezen, Liisa Volin et al.
We performed a retrospective analysis of the European Group for Blood and Marrow Transplantation database comparing the outcomes of multiple myeloma patients who received tandem autologous followed by allogeneic PSCT (auto-allo) with the outcomes of patients who underwent a reduced intensity conditi...
Laurent Garderet, Gordon Cook, Holger W. Auner, Benedetto Bruno et al.
Major improvements have been made in the treatment of myeloma. However, all patients, perhaps with some exceptions, eventually relapse, even after autologous stem cell transplantation (ASCT). In that setting, the combinations of new drugs, namely the IMiDs and the proteasome inhibitors along with st...
Curly Morris, Simona Iacobelli, Gösta Gahrton, Anja van Biezen et al.
We have recently reported on the outcome of autologous transplantation in the rare myelomas (IgD, IgE, IgM, and nonsecretory [NS]) but there is no real information on the outcome of these conditions after allogeneic transplantation. We used the European Group for Blood and Marrow Transplantation mye...
Firoozeh Sahebi, Simona Iacobelli, Anja van Biezen, Liisa Volin et al.
Abstract Background Despite the advances in the treatment of multiple myeloma using new targeted therapies and autologous hematopoietic stem cell transplant (HSCT) the disease remains largely incurable. Recent efforts in using reduced intensity allogeneic HSCT have been hampered by increased allogra...
Gordon Cook, Laurent Garderet, Anja van Biezen, Anja Henseler et al.
Abstract Abstract 4115 Introduction: Polyneuropathy, organomegaly, endocrinopathy, skin changes associated with a paraproteinaemia (POEMS syndrome) is a rare paraneoplastic syndrome secondary to a plasma cell dyscrasia. Effective treatment, including ASCT, of the underlying plasma cell dyscrasia can...
Curly Morris, Marijke Scholten, Liesbeth C. de Wreede, Anja van Biezen et al.
Abstract Abstract 2397 Introduction. DMSO is the universally used cryoprotectant for freezing peripheral blood stem cell for autologous transplantation. DMSO has a significant side effect profile including vasoconstriction, nausea and vomiting and with transplant related mortality now in the region ...