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Results for “"Antônio Lima Braga"”

5 results

Thymoquinone is knocking at the door of clinical trial

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Mohammed Torequl Islam, Nasreen Sultana, Thoufiqul Alam Riaz, Jannatul Ferdous et al.

Journal: International Archives of MedicineYear: 2016Citations: 22

This review aimed at summarizing the therapeutic potentials in a mechanistic context of a vastly studied quinone, naturally derived product from the seed oil of Nigella sativa called thymoquinone (TQ). The proposed underlyng mechanism may be attributed to its lowdose-mediated antioxidative effect wh...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Toxicogenetic study of omeprazole and the modulatory effects of retinol palmitate and ascorbic acid on Allium cepa

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Antônio Lima Braga, Ag‐Anne Pereira Melo de Menezes, José Victor de Oliveira Santos, Antonielly Campinho dos Reis et al.

Journal: ChemosphereYear: 2018Citations: 19

Omeprazole (OME) is a proton pump inhibitor used for the treatment of various gastric and intestinal disease; however, studies on its effects on the genetic materials are still restricted. The present study aimed to evaluate possible toxicogenic effects of OME in Allium cepa meristems with the appli...

Life SciencesBiochemistry, Genetics and Molecular BiologyCancer Research
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Cytogenotoxicological defense of retinyl palmitate in the front damage of antineoplastics

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Ricardo Melo de Carvalho, Rai Pablo de Sousa Aguiar, Muhammad Torequl Islam, Marcus Vinícius Oliveira Barros de Alencar et al.

Journal: Experimental and Toxicologic PathologyYear: 2017Citations: 9

Cancer, the multifactorial pathology and to date is the most lethal causes of death in the world. Cyclophosphamide (CPA) and doxorubicin (DOX) are the individually or combindly used two anticancer drugs. The antineoplastic drugs-mediated genetic instability can be overcome by using antioxidants. The...

Health SciencesMedicinePublic Health, Environmental and Occupational Health
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Phytanic acid, a daily consumed chlorophyll-yielded phytol bio-metabolite: A comprehensive review

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Torequl Islam Md., S. Ali Eunus, Melo de Carvalho Ricardo, Fernanda Correia Jardim Paz Marcia et al.

Journal: African Journal of Pharmacy and PharmacologyYear: 2016Citations: 5

An important chlorophyll-derived diterpenoid essential oil, phytol (PYT) bio-metabolite, phytanic acid (PA) has a number of pathophysiological contributions. The PA metabolism and its plasma levels associated phenomena are continuously being researched on. This study aims to look at the complete cur...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiochemistryOpen Access
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Protective effects of ascorbic acid against anticancer drug-induced oxidative stress and genotoxic damage in Saccharomyces cerevisiae

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Ana M. Mata, Reyca Rodrigues e Silva, Antônio Lima Braga, Ricardo Melo de Carvalho et al.

Journal: 3 BiotechYear: 2025Citations: 1

The widely used dietary antioxidant ascorbic acid (AA) is evident to possess protective effects against many chronic diseases. This study aimed to evaluate the effects of AA on oxidative stress and genotoxic damage caused by 5-fluorouracil (5-FU), docetaxel (DOCE), and tamoxifen (TAMOX) in two profi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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