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Results for “"Arkajyoti Paul"”

16+ results

Membrane stabilization as a mechanism of the anti-inflammatory activity of ethanolic root extract of Choi (Piper chaba)

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Samina Yesmin, Arkajyoti Paul, Tarannum Naz, A. B. M. Atiqur Rahman et al.

Journal: Clinical PhytoscienceYear: 2020Citations: 257

Abstract Background This experiment is conducted to evaluate the anti-inflammatory effect of Piper chaba roots. Methods The in-vitro anti-inflammatory activity of Piper chaba was carried out by human red blood cell (HRBC) membrane stabilization method which includes heat-induced hemolysis and hypo t...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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Investigation of the Biological Activities and Characterization of Bioactive Constituents of Ophiorrhiza rugosa var. prostrata (D.Don) & Mondal Leaves through In Vivo, In Vitro, and In Silico Approaches

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Md. Adnan, Md. Nazim Uddin Chy, A.T.M. Mostafa Kamal, Md Obyedul Kalam Azad et al.

Journal: MoleculesYear: 2019Citations: 132

Ophiorrhiza rugosa var. prostrata is one of the most frequently used ethnomedicinal plants by the indigenous communities of Bangladesh. This study was designed to investigate the antidiarrheal, anti-inflammatory, anthelmintic and antibacterial activities of the ethanol extract of O. rugosa leaves (E...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Immunoinformatics-guided design of an epitope-based vaccine against severe acute respiratory syndrome coronavirus 2 spike glycoprotein

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Ahmed Rakib, Saad Ahmed Sami, Nusrat Jahan Mimi, Md. Mustafiz Chowdhury et al.

Journal: Computers in Biology and MedicineYear: 2020Citations: 97

Aims With a large number of fatalities, coronavirus disease-2019 (COVID-19) has greatly affected human health worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes COVID-19. The World Health Organization has declared a global pandemic of this contagious dis...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Biochemical and Computational Approach of Selected Phytocompounds from Tinospora crispa in the Management of COVID-19

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Ahmed Rakib, Arkajyoti Paul, Md. Nazim Uddin Chy, Saad Ahmed Sami et al.

Journal: MoleculesYear: 2020Citations: 96

A pandemic caused by the novel coronavirus (SARS-CoV-2 or COVID-19) began in December 2019 in Wuhan, China, and the number of newly reported cases continues to increase. More than 19.7 million cases have been reported globally and about 728,000 have died as of this writing (10 August 2020). Recently...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Antipyretic and hepatoprotective potential of <i>Tinospora crispa</i> and investigation of possible lead compounds through in silico approaches

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Ahmed Rakib, Shahriar Ahmed, Md. Ashiqul Islam, Abdul Haye et al.

Journal: Food Science & NutritionYear: 2019Citations: 75

Abstract This research describes an investigation of the antipyretic and hepatoprotective properties of both a crude organic extract and various subfractions of the ethnomedicinal plant Tinospora crispa , using appropriate animal models. In an attempt to identify potential lead hepatoprotective comp...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Phytol anti-inflammatory activity: Pre-clinical assessment and possible mechanism of action elucidation

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Muhammad Torequl Islam, Seyed Abdulmajid Ayatollahi, S. M. Neamul Kabir Zihad, Nazifa Sifat et al.

Journal: Cellular and Molecular BiologyYear: 2020Citations: 68

Phytol (PHY) is an acyclic natural diterpene alcohol and a chlorophyll constituent that exhibits several pharmacological effects, such as anticancer, antioxidant, and antimicrobial. Here, we aimed to assess the PHY anti-inflammatory effect in vitro and in vivo, and to deepen knowledge on the possibl...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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GC-MS Phytochemical Profiling, Pharmacological Properties, and In Silico Studies of Chukrasia velutina Leaves: A Novel Source for Bioactive Agents

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Israt Jahan, Marzia Rahman Tona, Sanjida Sharmin, Mohammed Aktar Sayeed et al.

Journal: MoleculesYear: 2020Citations: 65

Chukrasia velutina is a local medicinal plant commonly known as chikrassy in Bangladesh, India, China, and other South Asian countries. The leaves, bark, and seeds are vastly used as herbal medicine for fever and diarrhea, and its leaves essential oils are used for antimicrobial purposes. In this st...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Pharmacological evidence for the use of Cissus assamica as a medicinal plant in the management of pain and pyrexia

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Trishala Dutta, Arkajyoti Paul, Mohuya Majumder, Ramiz Ahmed Sultan et al.

Journal: Biochemistry and Biophysics ReportsYear: 2019Citations: 52

The existing therapeutic agents for the management of pain and pyrexia are not very efficient and accompanied by numerous side effects. Thus, new effective agents are the most needed. The present study investigates bioactivities and phytochemical screening of different parts of Cissus assamica (Vita...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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In vivo and in vitro pharmacological activities of Tacca integrifolia rhizome and investigation of possible lead compounds against breast cancer through in silico approaches

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Shahriar Ahmed, Ahmed Rakib, Md. Ashiqul Islam, Bibi Humayra Khanam et al.

Journal: Clinical PhytoscienceYear: 2019Citations: 52

Abstract Background The study was conducted to evaluate the analgesic, anti-inflammatory, antipyretic properties of ethanolic extract of Tacca integrifolia rhizome (EETI) in mice and cytotoxic effects in brine shrimp nauplii followed by a PASS prediction study for some isolated compounds of T. integ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Computational and Pharmacological Studies on the Antioxidant, Thrombolytic, Anti-Inflammatory, and Analgesic Activity of Molineria capitulata

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Mohammad Ashiqur Rahman Bhuiyan Shovo, Marzia Rahman Tona, Jannatul Mouah, Fayza Islam et al.

Journal: Current Issues in Molecular BiologyYear: 2021Citations: 43

Molineria capitulata is an ornamental plant that has traditionally been used to treat several chronic diseases. The present study was designed to examine the antioxidant, cytotoxic, thrombolytic, anti-inflammatory, and analgesic activities of a methanolic extract of M. capitulata leaves (MEMC) using...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Appraisals of the Bangladeshi Medicinal Plant Calotropis gigantea Used by Folk Medicine Practitioners in the Management of COVID-19: A Biochemical and Computational Approach

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Mycal Dutta, Mohammad Nezam, S. Chowdhury, Ahmed Rakib et al.

Journal: Frontiers in Molecular BiosciencesYear: 2021Citations: 36

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first recognized in Wuhan in late 2019 and, since then, had spread globally, eventually culminating in the ongoing pandemic. As there is a lack of targeted therapeutics, there is certain opportunity for the scientific community to deve...

Physical SciencesMaterials ScienceBiomaterialsOpen Access
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Chemical Profiles and Pharmacological Properties with in Silico Studies on Elatostema papillosum Wedd

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Md. Zia Uddin, Arkajyoti Paul, Ahmed Rakib, Saad Ahmed Sami et al.

Journal: MoleculesYear: 2021Citations: 36

The current study attempted, for the first time, to qualitatively and quantitatively determine the phytochemical components of Elatostema papillosum methanol extract and their biological activities. The present study represents an effort to correlate our previously reported biological activities wit...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Pharmacological studies on the antinociceptive, anxiolytic and antidepressant activity of <i>Tinospora crispa</i>

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Ahmed Rakib, Shahriar Ahmed, Md. Ashiqul Islam, Mir Muhammad Nasir Uddin et al.

Journal: Phytotherapy ResearchYear: 2020Citations: 30

Pharmacological studies were performed in mice on the methanol extract of Tinospora crispa (TC), and of its hexane (HF) and chloroform (CF) fractions. Significant antinociceptive activity was observed for TC, HF, and CF in the acetic acid-induced writhing and formalin-induced paw licking tests. Anxi...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Anthelmintic activity of Piper sylvaticum Roxb. (family: Piperaceae): In vitro and in silico studies

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Arkajyoti Paul, Md. Adnan, Mohuya Majumder, Niloy Kar et al.

Journal: Clinical PhytoscienceYear: 2018Citations: 29

The present study was conducted to investigate the anthelmintic activity of methanol extract of Piper sylvaticum stem (MEPSS) in experimental model followed by in silico molecular docking study and ADME/T analysis. Anthelmintic activity was determined by an aquarium worm (Tubifex tubifex). Then, mol...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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In silico analysis of indole-3-carbinol and its metabolite DIM as EGFR tyrosine kinase inhibitors in platinum resistant ovarian cancer vis a vis ADME/T property analysis

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Raju Dash, S. M. Zahid Hosen, Md. Rezaul Karim, Mohammad Shah Hafez Kabir et al.

Journal: Journal of Applied Pharmaceutical ScienceYear: 2015Citations: 26

Epidermal Growth Factor Receptor (EGFR) is one of the four members of the Human Epidermal Receptor (HER) family, which is deregulated and over expressed in platinum resistant ovarian cancer. Thus, targeting EGFR receptor along with platinum drugs is one of the major strategies to increase the platin...

Physical SciencesChemistryOrganic ChemistryOpen Access
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